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GeneCards® Hot Genes
The following is a list of "hot" genes: those
that have been most frequently requested at the GeneCards home site since Dec 21, 2007
sorted by frequency of access.
- SORT1 sortilin 1
- EGFR epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
- BRCA1 breast cancer 1, early onset
- EPHB4 EPH receptor B4
- VIM vimentin
- TP53 tumor protein p53 (Li-Fraumeni syndrome)
- NR4A2 nuclear receptor subfamily 4, group A, member 2
- DMD dystrophin (muscular dystrophy, Duchenne and Becker types)
- HGF hepatocyte growth factor (hepapoietin A; scatter factor)
- INSR insulin receptor
- CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- PCNA proliferating cell nuclear antigen
- NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
- CREBBP CREB binding protein (Rubinstein-Taybi syndrome)
- FBN1 fibrillin 1
- EP300 E1A binding protein p300
- BRCA2 breast cancer 2, early onset
- ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
- FGF2 fibroblast growth factor 2 (basic)
- AKT1 v-akt murine thymoma viral oncogene homolog 1
- ADRB2 adrenergic, beta-2-, receptor, surface
- BCL2 B-cell CLL/lymphoma 2
- PSAP prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)
- HEXB hexosaminidase B (beta polypeptide)
- TOP2A topoisomerase (DNA) II alpha 170kDa
- BMP4 bone morphogenetic protein 4
- PTEN phosphatase and tensin homolog (mutated in multiple advanced cancers 1)
- APP amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
- JAK2 Janus kinase 2 (a protein tyrosine kinase)
- FYN FYN oncogene related to SRC, FGR, YES
- ABL1 v-abl Abelson murine leukemia viral oncogene homolog 1
- HEXA hexosaminidase A (alpha polypeptide)
- ATM ataxia telangiectasia mutated
- MAPK8 mitogen-activated protein kinase 8
- PARP1 poly (ADP-ribose) polymerase family, member 1
- GJA1 gap junction protein, alpha 1, 43kDa
- GAPDH glyceraldehyde-3-phosphate dehydrogenase
- APOE apolipoprotein E
- SOD1 superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))
- ERCC1 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
- VEGFA vascular endothelial growth factor A
- AR androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
- CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
- RB1 retinoblastoma 1 (including osteosarcoma)
- CDH1 cadherin 1, type 1, E-cadherin (epithelial)
- HIF1A hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
- ACHE acetylcholinesterase (Yt blood group)
- MAPK14 mitogen-activated protein kinase 14
- GRB2 growth factor receptor-bound protein 2
- APC adenomatosis polyposis coli
- MTHFR 5,10-methylenetetrahydrofolate reductase (NADPH)
- NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
- MET met proto-oncogene (hepatocyte growth factor receptor)
- TNF tumor necrosis factor (TNF superfamily, member 2)
- ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
- HFE hemochromatosis
- ESR1 estrogen receptor 1
- STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
- MAPK1 mitogen-activated protein kinase 1
- HBB hemoglobin, beta
- BTK Bruton agammaglobulinemia tyrosine kinase
- FGFR1 fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
- ATP7B ATPase, Cu++ transporting, beta polypeptide
- PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
- BCL2L1 BCL2-like 1
- CCR5 chemokine (C-C motif) receptor 5
- PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide
- BLM Bloom syndrome
- BDNF brain-derived neurotrophic factor
- VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
- RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
- FMR1 fragile X mental retardation 1
- GCK glucokinase (hexokinase 4, maturity onset diabetes of the young 2)
- PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- CASP9 caspase 9, apoptosis-related cysteine peptidase
- RELA v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)
- MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
- PPARG peroxisome proliferator-activated receptor gamma
- CD4 CD4 molecule
- JUN jun oncogene
- MYC v-myc myelocytomatosis viral oncogene homolog (avian)
- CASP8 caspase 8, apoptosis-related cysteine peptidase
- A2M alpha-2-macroglobulin
- PSEN1 presenilin 1 (Alzheimer disease 3)
- KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
- ICAM1 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
- ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
- CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
- MDM2 Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)
- IGF1 insulin-like growth factor 1 (somatomedin C)
- EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
- IL6 interleukin 6 (interferon, beta 2)
- GSN gelsolin (amyloidosis, Finnish type)
- MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- BAD BCL2-antagonist of cell death
- ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- LPL lipoprotein lipase
- BAX BCL2-associated X protein
- NOS1 nitric oxide synthase 1 (neuronal)
- NTRK1 neurotrophic tyrosine kinase, receptor, type 1
- GSTM1 glutathione S-transferase M1
- MAPK3 mitogen-activated protein kinase 3
- CDC2 cell division cycle 2, G1 to S and G2 to M
- GBA glucosidase, beta; acid (includes glucosylceramidase)
- ATP7A ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)
- INS insulin
- NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
- TGFB1 transforming growth factor, beta 1
- ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
- ARSA arylsulfatase A
- CDK4 cyclin-dependent kinase 4
- IL1B interleukin 1, beta
- E2F1 E2F transcription factor 1
- ARNT aryl hydrocarbon receptor nuclear translocator
- CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- BRAF v-raf murine sarcoma viral oncogene homolog B1
- ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
- TUBB tubulin, beta
- WRN Werner syndrome
- MAPK9 mitogen-activated protein kinase 9
- CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
- VWF von Willebrand factor
- ESR2 estrogen receptor 2 (ER beta)
- ATF4 activating transcription factor 4 (tax-responsive enhancer element B67)
- BLNK B-cell linker
- PIN1 protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1
- SHC1 SHC (Src homology 2 domain containing) transforming protein 1
- CCND1 cyclin D1
- NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
- NOS2A nitric oxide synthase 2A (inducible, hepatocytes)
- CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
- ACADM acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
- AOC3 amine oxidase, copper containing 3 (vascular adhesion protein 1)
- GSTP1 glutathione S-transferase pi
- GSTT1 glutathione S-transferase theta 1
- CASP3 caspase 3, apoptosis-related cysteine peptidase
- BIRC5 baculoviral IAP repeat-containing 5 (survivin)
- PDGFRA platelet-derived growth factor receptor, alpha polypeptide
- G6PD glucose-6-phosphate dehydrogenase
- SOX9 SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)
- HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- CDK5 cyclin-dependent kinase 5
- PRNP prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)
- KDR kinase insert domain receptor (a type III receptor tyrosine kinase)
- STAT1 signal transducer and activator of transcription 1, 91kDa
- CHEK2 CHK2 checkpoint homolog (S. pombe)
- CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
- HNF4A hepatocyte nuclear factor 4, alpha
- CCL2 chemokine (C-C motif) ligand 2
- HMOX1 heme oxygenase (decycling) 1
- MAP2K1 mitogen-activated protein kinase kinase 1
- KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- SREBF1 sterol regulatory element binding transcription factor 1
- CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
- TUBA8 tubulin, alpha 8
- FAS Fas (TNF receptor superfamily, member 6)
- ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
- PAX6 paired box 6
- ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
- MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
- RET ret proto-oncogene
- PLAU plasminogen activator, urokinase
- ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- SGK serum/glucocorticoid regulated kinase
- ACTA1 actin, alpha 1, skeletal muscle
- FGFR2 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome)
- NQO1 NAD(P)H dehydrogenase, quinone 1
- JAK3 Janus kinase 3 (a protein tyrosine kinase, leukocyte)
- NOTCH1 Notch homolog 1, translocation-associated (Drosophila)
- ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
- ACTB actin, beta
- PTGDS prostaglandin D2 synthase 21kDa (brain)
- MECP2 methyl CpG binding protein 2 (Rett syndrome)
- LDLR low density lipoprotein receptor (familial hypercholesterolemia)
- HLA-B major histocompatibility complex, class I, B
- COL1A1 collagen, type I, alpha 1
- SMAD4 SMAD family member 4
- RAF1 v-raf-1 murine leukemia viral oncogene homolog 1
- FLNB filamin B, beta (actin binding protein 278)
- EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
- TPI1 triosephosphate isomerase 1
- RHOA ras homolog gene family, member A
- LCK lymphocyte-specific protein tyrosine kinase
- MGMT O-6-methylguanine-DNA methyltransferase
- ACTN4 actinin, alpha 4
- DRD2 dopamine receptor D2
- GHR growth hormone receptor
- FRAP1 FK506 binding protein 12-rapamycin associated protein 1
- H19 H19, imprinted maternally expressed untranslated mRNA
- FASLG Fas ligand (TNF superfamily, member 6)
- FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- EGF epidermal growth factor (beta-urogastrone)
- RUNX1 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)
- CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
- NF1 neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)
- TERT telomerase reverse transcriptase
- ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
- SOD2 superoxide dismutase 2, mitochondrial
- VCP valosin-containing protein
- PRKG1 protein kinase, cGMP-dependent, type I
- CASR calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)
- MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
- CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
- HPRT1 hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)
- PRKCG protein kinase C, gamma
- HTT huntingtin
- TGFB3 transforming growth factor, beta 3
- PBX1 pre-B-cell leukemia homeobox 1
- IL8 interleukin 8
- RARA retinoic acid receptor, alpha
- SP1 Sp1 transcription factor
- AKT2 v-akt murine thymoma viral oncogene homolog 2
- LEPR leptin receptor
- NGFR nerve growth factor receptor (TNFR superfamily, member 16)
- ERCC2 excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)
- NTRK2 neurotrophic tyrosine kinase, receptor, type 2
- CP ceruloplasmin (ferroxidase)
- MPO myeloperoxidase
- CXCR4 chemokine (C-X-C motif) receptor 4
- THBS1 thrombospondin 1
- SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
- CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
- PML promyelocytic leukemia
- WNT2 wingless-type MMTV integration site family member 2
- CDK2 cyclin-dependent kinase 2
- ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
- FN1 fibronectin 1
- NOS3 nitric oxide synthase 3 (endothelial cell)
- ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
- MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
- MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
- CDC42 cell division cycle 42 (GTP binding protein, 25kDa)
- NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
- A1BG alpha-1-B glycoprotein
- IL2 interleukin 2
- LIPA lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
- PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
- FGFR3 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)
- ADRB1 adrenergic, beta-1-, receptor
- CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence
- ASS1 argininosuccinate synthetase 1
- WNT1 wingless-type MMTV integration site family, member 1
- COMT catechol-O-methyltransferase
- ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
- TTR transthyretin (prealbumin, amyloidosis type I)
- FUK fucokinase
- ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- IGF1R insulin-like growth factor 1 receptor
- LEP leptin (obesity homolog, mouse)
- RYR1 ryanodine receptor 1 (skeletal)
- MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- CHUK conserved helix-loop-helix ubiquitous kinase
- ABAT 4-aminobutyrate aminotransferase
- DMPK dystrophia myotonica-protein kinase
- SYK spleen tyrosine kinase
- ALK anaplastic lymphoma kinase (Ki-1)
- CYCS cytochrome c, somatic
- CD44 CD44 molecule (Indian blood group)
- GNAS GNAS complex locus
- ADIPOQ adiponectin, C1Q and collagen domain containing
- FOS v-fos FBJ murine osteosarcoma viral oncogene homolog
- WT1 Wilms tumor 1
- B2M beta-2-microglobulin
- LMNA lamin A/C
- CSF3 colony stimulating factor 3 (granulocyte)
- GLA galactosidase, alpha
- SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
- CHEK1 CHK1 checkpoint homolog (S. pombe)
- CTSD cathepsin D
- SMAD3 SMAD family member 3
- WNT5A wingless-type MMTV integration site family, member 5A
- NEFL neurofilament, light polypeptide 68kDa
- ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
- NR3C2 nuclear receptor subfamily 3, group C, member 2
- DCN decorin
- EGR1 early growth response 1
- PRKCA protein kinase C, alpha
- GRN granulin
- PAK1 p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
- GFAP glial fibrillary acidic protein
- CHRNA7 cholinergic receptor, nicotinic, alpha 7
- PTPN11 protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
- APOB apolipoprotein B (including Ag(x) antigen)
- PPARA peroxisome proliferator-activated receptor alpha
- HADHA hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
- F7 coagulation factor VII (serum prothrombin conversion accelerator)
- AVPR2 arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)
- HLA-G HLA-G histocompatibility antigen, class I, G
- VAV1 vav 1 guanine nucleotide exchange factor
- C3 complement component 3
- TLR4 toll-like receptor 4
- BRCC3 BRCA1/BRCA2-containing complex, subunit 3
- ADRB3 adrenergic, beta-3-, receptor
- TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
- TYR tyrosinase (oculocutaneous albinism IA)
- LRRK2 leucine-rich repeat kinase 2
- ERCC6 excision repair cross-complementing rodent repair deficiency, complementation group 6
- DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
- SQSTM1 sequestosome 1
- ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
- MAOA monoamine oxidase A
- BCR breakpoint cluster region
- HDAC1 histone deacetylase 1
- PECAM1 platelet/endothelial cell adhesion molecule (CD31 antigen)
- ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
- GSR glutathione reductase
- GSK3B glycogen synthase kinase 3 beta
- ELN elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)
- OXA1L oxidase (cytochrome c) assembly 1-like
- PTPRC protein tyrosine phosphatase, receptor type, C
- ALB albumin
- HNF1A HNF1 homeobox A
- S100A1 S100 calcium binding protein A1
- KCNH2 potassium voltage-gated channel, subfamily H (eag-related), member 2
- MYH7 myosin, heavy chain 7, cardiac muscle, beta
- GALC galactosylceramidase
- SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
- NOD2 nucleotide-binding oligomerization domain containing 2
- CD14 CD14 molecule
- TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
- ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
- XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
- ADORA1 adenosine A1 receptor
- FLT3 fms-related tyrosine kinase 3
- SHH sonic hedgehog homolog (Drosophila)
- DPP4 dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)
- UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
- LAMP1 lysosomal-associated membrane protein 1
- GUSB glucuronidase, beta
- DST dystonin
- CAT catalase
- AIRE autoimmune regulator
- MSH6 mutS homolog 6 (E. coli)
- TOP1 topoisomerase (DNA) I
- TBP TATA box binding protein
- HMGB1 high-mobility group box 1
- MAPT microtubule-associated protein tau
- VHL von Hippel-Lindau tumor suppressor
- SHBG sex hormone-binding globulin
- ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
- IL8RB interleukin 8 receptor, beta
- CREB1 cAMP responsive element binding protein 1
- WTAP Wilms tumor 1 associated protein
- CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
- IFNG interferon, gamma
- CD59 CD59 molecule, complement regulatory protein
- AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
- PGR progesterone receptor
- ADORA2A adenosine A2a receptor
- CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
- YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
- CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
- ACTG1 actin, gamma 1
- AGTR1 angiotensin II receptor, type 1
- JAK1 Janus kinase 1 (a protein tyrosine kinase)
- CRP C-reactive protein, pentraxin-related
- BCHE butyrylcholinesterase
- ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
- PON1 paraoxonase 1
- GALK1 galactokinase 1
- CASP7 caspase 7, apoptosis-related cysteine peptidase
- MME membrane metallo-endopeptidase
- GAL galanin prepropeptide
- CAV1 caveolin 1, caveolae protein, 22kDa
- THRA thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
- LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
- FGF1 fibroblast growth factor 1 (acidic)
- SPTB spectrin, beta, erythrocytic (includes spherocytosis, clinical type I)
- JUP junction plakoglobin
- HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
- PARK7 Parkinson disease (autosomal recessive, early onset) 7
- IRS1 insulin receptor substrate 1
- NGFB nerve growth factor, beta polypeptide
- TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
- IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- CRYAB crystallin, alpha B
- SELL selectin L (lymphocyte adhesion molecule 1)
- IL10 interleukin 10
- AGER advanced glycosylation end product-specific receptor
- NCAM1 neural cell adhesion molecule 1
- IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
- MMP1 matrix metallopeptidase 1 (interstitial collagenase)
- ATR ataxia telangiectasia and Rad3 related
- SLC6A4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- APOA1 apolipoprotein A-I
- SLC6A2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
- TXN thioredoxin
- RPS27A ribosomal protein S27a
- ALDH1A1 aldehyde dehydrogenase 1 family, member A1
- CEBPB CCAAT/enhancer binding protein (C/EBP), beta
- SMAD2 SMAD family member 2
- CLU clusterin
- GADD45A growth arrest and DNA-damage-inducible, alpha
- TH tyrosine hydroxylase
- NBN nibrin
- F13A1 coagulation factor XIII, A1 polypeptide
- POLG polymerase (DNA directed), gamma
- PICK1 protein interacting with PRKCA 1
- MAPK10 mitogen-activated protein kinase 10
- LTA lymphotoxin alpha (TNF superfamily, member 1)
- ADA adenosine deaminase
- NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
- IL1A interleukin 1, alpha
- HSPA4 heat shock 70kDa protein 4
- GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- CAMK2G calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma
- HDAC9 histone deacetylase 9
- ACACA acetyl-Coenzyme A carboxylase alpha
- OPRM1 opioid receptor, mu 1
- TLR2 toll-like receptor 2
- OGG1 8-oxoguanine DNA glycosylase
- ADRA2A adrenergic, alpha-2A-, receptor
- FADD Fas (TNFRSF6)-associated via death domain
- CCR2 chemokine (C-C motif) receptor 2
- COL2A1 collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)
- RXRA retinoid X receptor, alpha
- ENO1 enolase 1, (alpha)
- SELP selectin P (granule membrane protein 140kDa, antigen CD62)
- ALS2 amyotrophic lateral sclerosis 2 (juvenile)
- KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1
- PSEN2 presenilin 2 (Alzheimer disease 4)
- THRB thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
- ANXA2 annexin A2
- NPY neuropeptide Y
- AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
- LRP1 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
- CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
- CCL5 chemokine (C-C motif) ligand 5
- LCT lactase
- HLA-A major histocompatibility complex, class I, A
- BMP2 bone morphogenetic protein 2
- ATRX alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)
- CD40 CD40 molecule, TNF receptor superfamily member 5
- MEF2A myocyte enhancer factor 2A
- F2 coagulation factor II (thrombin)
- PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- FASN fatty acid synthase
- TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
- ARAF v-raf murine sarcoma 3611 viral oncogene homolog
- PARK2 Parkinson disease (autosomal recessive, juvenile) 2, parkin
- CETP cholesteryl ester transfer protein, plasma
- TGFBR1 transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)
- PC pyruvate carboxylase
- KLF6 Kruppel-like factor 6
- IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- ATXN1 ataxin 1
- ACP1 acid phosphatase 1, soluble
- SELE selectin E (endothelial adhesion molecule 1)
- TF transferrin
- BCL6 B-cell CLL/lymphoma 6 (zinc finger protein 51)
- SCARB1 scavenger receptor class B, member 1
- ALOX5 arachidonate 5-lipoxygenase
- APAF1 apoptotic peptidase activating factor 1
- SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
- GPI glucose phosphate isomerase
- UBE3A ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
- TPP1 tripeptidyl peptidase I
- TIMP1 TIMP metallopeptidase inhibitor 1
- ADAM17 ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)
- AURKA aurora kinase A
- CD36 CD36 molecule (thrombospondin receptor)
- NRG1 neuregulin 1
- FAP fibroblast activation protein, alpha
- TAZ tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)
- BDKRB2 bradykinin receptor B2
- ASPA aspartoacylase (Canavan disease)
- P2RX7 purinergic receptor P2X, ligand-gated ion channel, 7
- CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- GH1 growth hormone 1
- SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
- ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
- HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
- PHB prohibitin
- IL18 interleukin 18 (interferon-gamma-inducing factor)
- DNAH8 dynein, axonemal, heavy chain 8
- RICTOR
- AHR aryl hydrocarbon receptor
- FSHR follicle stimulating hormone receptor
- ADSL adenylosuccinate lyase
- TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
- MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase)
- HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
- ASL argininosuccinate lyase
- APOD apolipoprotein D
- TPMT thiopurine S-methyltransferase
- CRH corticotropin releasing hormone
- ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
- PTPRF protein tyrosine phosphatase, receptor type, F
- HTR2A 5-hydroxytryptamine (serotonin) receptor 2A
- LAMA1 laminin, alpha 1
- HES1 hairy and enhancer of split 1, (Drosophila)
- APTX aprataxin
- HADHB hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
- SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
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