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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

XAB2 Gene

protein-coding   GIFtS: 62
GCID: GC19M007684

XPA binding protein 2

 Explore 4 diseases affiliated with
XAB2 via our new
 Human Malady Compendium 
Biological research products
for XAB2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
XPA Binding Protein 21 2     Crn-Related Protein Kim12
HCNP1 2 3     Pre-MRNA-Splicing Factor SYF12
SYF11 2 3     SYF1 Homolog, RNA Splicing Factor2
HCRN1 2     KIAA11773
NTC901 2     Protein HCNP3
XPA-Binding Protein 22 3     

External Ids:    HGNC: 140891   Entrez Gene: 569492   Ensembl: ENSG000000769247   OMIM: 6108505   UniProtKB: Q9HCS73   

Export aliases for XAB2 gene to outside databases

Previous GC identifers: GC00U913006 GC19M007590 GC19M007354


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SYF1_HUMAN, Q9HCS7
Function: Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing

Gene Wiki entry for XAB2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_077812.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the XAB2 gene promoter:
         GR   Sp1   GCNF   Lmo2   Nkx2-5   GCNF-1   SEF-1 (1)   STAT3   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): XAB2 promoter sequence
   Search SABiosciences Chromatin IP Primers for XAB2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XAB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.3

XAB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
XAB2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M007684:  view genomic region     (about GC identifiers)

Start:
7,684,411 bp from pter      End:
7,694,451 bp from pter
Size:
10,041 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SYF1_HUMAN, Q9HCS7 (See protein sequence)
Recommended Name: Pre-mRNA-splicing factor SYF1  
Size: 855 amino acids; 100010 Da
Subunit: Associates with RNA polymerase II, the TCR-specific proteins CKN1/CSA and ERCC6/CSB, and XPA. Identified in
the spliceosome C complex
Subcellular location: Nucleus (By similarity). Note=Detected in the splicing complex carrying pre-mRNA (By similarity)
Sequence caution: Sequence=AAF86951.1; Type=Frameshift; Positions=314, 411, 426, 429, 468; Sequence=AAH08778.1;
Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAB84861.1; Type=Miscellaneous
discrepancy; Note=Alternative splicing. Incomplete sequence;
Secondary accessions: Q8TET6 Q96HB0 Q96IW0 Q9NRG6 Q9ULP3

Explore the universe of human proteins at neXtProt for XAB2: NX_Q9HCS7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9HCS7

  • XAB2 Protein expression data from MOPED and PaxDb:    About this image 
    XAB2 Protein Expression
    REFSEQ proteins: NP_064581.2  
    ENSEMBL proteins: 
     ENSP00000351137   ENSP00000438225  
    Reactome Protein details: Q9HCS7
    Human Recombinant Protein Products for XAB2: 
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    OriGene Custom Protein Services for XAB2 
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    Novus Biologicals XAB2 Protein
    Novus Biologicals XAB2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for XAB2

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IC10944529
    GO:0005654nucleoplasm TAS--
    GO:0071013catalytic step 2 spliceosome IDA11991638

    XAB2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for XAB2


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    XAB2 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR003107 HAT
     IPR011990 TPR-like_helical
     IPR013105 TPR_2
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q9HCS7

    ProtoNet protein and cluster: Q9HCS7

    1 Blocks protein family: IPB003107 RNA-processing protein

    UniProtKB/Swiss-Prot: SYF1_HUMAN, Q9HCS7
    Similarity: Belongs to the crooked-neck family
    Similarity: Contains 14 HAT repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYF1_HUMAN, Q9HCS7
    Function: Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI10944529
         
    XAB2 for ontologies           About GeneDecksing


    Phenotypes:
         7 GenomeRNAi human phenotypes for XAB2:
     Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Decreased viability 
     Decreased viability of wild-ty  Increased gamma-H2AX phosphory  Low eccentricity cells 

         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Xab2):
     embryogenesis  mortality/aging 

    XAB2 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-outs for XAB2: Xab2tm2Tnka Xab2tm1Tnka
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for XAB2 

    miRNA
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    Inhib. RNA
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    Sirion Biotech Custom design and validation of potent shRNA sequences against XAB2 

    Gene Editing
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    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XAB2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Nucleotide Excision Repair
    Nucleotide Excision Repair1.00
    DNA Repair0.46
    Transcription-coupled NER (TC-NER)0.90
    2Formation of RNA Pol II elongation complex
    Dual incision reaction in TC-NER0.46
    Formation of transcription-coupled NER (TC-NER) repair complex0.46
    3Chks in Checkpoint Regulation
    DNA Repair Mechanisms0.32
    4mRNA Splicing - Major Pathway
    Spliceosome0.31

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for XAB2
        DNA Repair Mechanisms

    5        Reactome Pathways for XAB2
        DNA Repair
    Transcription-coupled NER (TC-NER)
    Formation of transcription-coupled NER (TC-NER) repair complex
    Dual incision reaction in TC-NER
    Nucleotide Excision Repair


    1         Kegg Pathway  (Kegg details for XAB2):
        Spliceosome


    XAB2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for XAB2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/78 Interacting proteins for XAB2 (Q9HCS71, 2, 3 ENSP000003511374) via UniProtKB, MINT, STRING, and/or I2D (see all 78)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPIEQ9UNP92, 3, ENSP000003127694MINT-8337068 MINT-8331976 I2D: score=4 STRING: ENSP00000312769
    SNW1Q135732, 3, ENSP000002615314MINT-8331965 MINT-8337057 I2D: score=1 STRING: ENSP00000261531
    POLR2AP249281, 3, ENSP000003149494EBI-295232,EBI-295301 I2D: score=4 STRING: ENSP00000314949
    GLIS2Q9BZE02, 3, ENSP000002623664MINT-4651467 I2D: score=2 STRING: ENSP00000262366
    ISY1Q9ULR02, 3, ENSP000003769734MINT-8337046 MINT-8331954 I2D: score=1 STRING: ENSP00000376973
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome IC11991638
    GO:0001824blastocyst development IEA--
    GO:0006281DNA repair TAS--
    GO:0006283transcription-coupled nucleotide-excision repair TAS--
    GO:0006289nucleotide-excision repair TAS--

    XAB2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for XAB2
    Search CenterWatch for drugs/clinical trials and news about XAB2 / SYF1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for XAB2 gene: 
    NM_020196.2  

    Unigene Cluster for XAB2:

    XPA binding protein 2
    Hs.9822  [show with all ESTs]
    Unigene Representative Sequence: AK074035
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358368(uc002mgx.3) ENST00000534844

    miRNA
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XAB2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XAB2

    Additional cDNA sequence: 

    AB026111.1 AB033003.1 AF226051.1 AF258567.1 AF272147.1 AK025858.1 AK074035.1 BC007208.1 
    BC008778.1 CR749864.1 

    7 DOTS entries:

    DT.445941  DT.91755990  DT.97759948  DT.100833965  DT.95144979  DT.95133035  DT.95144980 

    24/272 AceView cDNA sequences (see all 272):

    AL534944 AA351089 AL525436 CR603946 BE208460 BE778200 AK074035 CA488373 
    F35523 BQ050225 BM836134 CR615981 BI772072 AB026111 BU845857 F04537 
    AL538943 BQ927835 BU153161 BM806807 BX424193 AB033003 BM913999 BM917523 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for XAB2    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19a · 19b
    SP1:                                                                                -                                                               
    SP2:                                                                                                                                                
    SP3:                                                                                                                                                
    SP4:                                                                                                                                                


    ECgene alternative splicing isoforms for XAB2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    XAB2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGCTGCTGG
    XAB2 Expression
    About this image
    See XAB2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for XAB2

    SOURCE GeneReport for Unigene cluster: Hs.9822
        SABiosciences Expression via Pathway-Focused PCR Array including XAB2: 

              DNA Repair in human mouse rat

    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XAB2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XAB2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for XAB2 gene from 8/31 species (see all 31)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Xab21 , 5 XPA binding protein 21, 5 89.04(n)1
    98.83(a)1
      8 (1.92 cM)5
    674391  NM_026156.21  NP_080432.11 
     36084215 
    lizard
    (Anolis carolinensis)
    Reptilia XAB26
    --
    84(a)
    1 ↔ 1
    2(103067133-103084767)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.19692 Xenopus laevis cDNA clone IMAGE4174459, partial cds 75.43(n)    BC060492.1 
    zebrafish
    (Danio rerio)
    Actinopterygii xab22 XPA binding protein 2 76.02(n)   387600  BC054579.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG61971 CG6197 64.71(n)
    64.11(a)
      36514  NM_137047.2  NP_610891.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C50F2.31 Protein C50F2.3 53.71(n)
    49.57(a)
      171970  NM_058849.5  NP_491250.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G287401 pre-mRNA-splicing factor SYF1 55.04(n)
    53.48(a)
      832986  NM_122757.3  NP_198226.1 
    rice
    (Oryza sativa)
    Liliopsida Os.331762 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 71.43(n)    AK101483.1 


    ENSEMBL Gene Tree for XAB2 (if available)
    TreeFam Gene Tree for XAB2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/341 NCBI SNPs in XAB2 are shown (see all 341    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1442864861,2
    --7683937(+) TGGTCC/GTGGGC 1 -- ds50010--------
    rs41348741,2
    H--7683959(-) CAGGCG/ACCAGA 1 -- ds50015Minor allele frequency- A:0.00NS EA 546
    rs729925541,2
    --7684003(+) CAGTTC/TCCAGA 1 -- ds50010--------
    rs41348731,2
    C,F,H--7684128(-) CCTCTC/AAGAGC 1 -- ds500110Minor allele frequency- A:0.04NS EA NA WA 964
    rs41348721,2
    C,F,H--7684171(-) AGGGCA/GATCCA 1 -- ds500115Minor allele frequency- G:0.04NS EA NA WA 1516
    rs41348711,2
    C,F--7684238(-) CCTCCG/ACTGCC 1 -- ds50015Minor allele frequency- A:0.02NS NA 438
    rs1510528731,2
    C--7684422(+) ACAAAC/TGTAGC 1 -- ut310--------
    rs41348701,2
    C,F--7684451(-) CCCCCATCC    
       CCC
    /-
    CTCCC
    2 -- ut311Minor allele frequency- -:0.15NS 178
    rs1431496421,2
    C--7684451(+) GGGAG-/GG    
       GGGAT
    GGGGG
    1 -- ut310--------
    rs755613811,2
    C--7684457(+) GGGGAG/TGGGGG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for XAB2 (7684411 - 7694451 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for XAB2
         1 CNV: 8863

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    XAB2 for disorders           About GeneDecksing

    OMIM gene information: 610850    OMIM disorders: --

    4 diseases for XAB2:    About MalaCards
    xeroderma pigmentosum    cockayne syndrome    multiple sclerosis    malaria

    2 diseases from the University of Copenhagen DISEASES database for XAB2:
    Cockayne syndrome     Xeroderma pigmentosum
    Human Genome Epidemiology (HuGE) Navigator: XAB2 (3 documents)

    Export disorders for XAB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for XAB2 gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with XAB2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. XAB2, a novel tetratricopeptide repeat protein, involved in transcription-coupled DNA repair and transcription. (PubMed id 10944529)1, 2, 3, 9 Nakatsu Y.... Tanaka K. (2000)
    2. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    5. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2 Hirosawa M.... Ohara O. (1999)
    6. Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair. (PubMed id 17981804)1, 9 Kuraoka I....Tanaka K. (2008)
    7. Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo. (PubMed id 16916636)1, 9 Fousteri M....Mullenders L.H. (2006)
    8. DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation. (PubMed id 22446626)1 Close P.... Svejstrup J.Q. (2012)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56949 HGNC: 14089 AceView: XAB2 Ensembl:ENSG00000076924 euGenes: HUgn56949
    ECgene: XAB2 Kegg: 56949 H-InvDB: XAB2

    (According to HUGE)
    About This Section
    HUGE: KIAA1177

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for XAB2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for XAB2 Genetics and Cytogenetics in Oncology and Haematology
    NIEHS-SNPshttp://egp.gs.washington.edu/data/hcnp/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for XAB2 gene:
    Search GeneIP for patents involving XAB2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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