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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

UCKL1 Gene

protein-coding GIFtS: 60
GCID: GC20M062571

uridine-cytidine kinase 1-like 1

(Previous name: uridine kinase-like 1 )
(Previous symbol: URKL1)

Explore 1 disease affiliated with
UCKL1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Uridine-Cytidine Kinase 1-Like 1¹ ²		UCK1L² ⁵
URKL1¹ ² ³ ⁵		FLJ20517¹
Uridine Kinase-Like 1¹ ²		UCK1-LIKE²
EC 2.7.1.48³ ⁸		Uridine-Cytidine Kinase-Like 1²

External Ids:	HGNC: 15938¹	Entrez Gene: 54963²	Ensembl: ENSG00000198276⁷	OMIM: 610866⁵	UniProtKB: Q9NWZ5³

Export aliases for UCKL1 gene to outside databases

Previous GC identifers: GC20M062041 GC20M059304

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: UCKL1_HUMAN, Q9NWZ5

Function: May contribute to UTP accumulation needed for blast transformation and proliferation

Gene Wiki entry for UCKL1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011333.6

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the UCKL1 gene promoter:
AhR Lmo2 LUN-1 AP-4 CUTL1 Arnt FOXL1 HOXA5 c-Myb
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: UCKL1 promoter sequence

Search SABiosciences Chromatin IP Primers for UCKL1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UCKL1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33 Ensembl cytogenetic band: 20q13.33 HGNC cytogenetic band: 20q13.33

UCKL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UCKL1 gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M062571: view genomic region (about GC identifiers)

Start:	62,571,182 bp from pter	End:	62,587,800 bp from pter
Size:	16,619 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UCKL1_HUMAN, Q9NWZ5 (See protein sequence)

Recommended Name: Uridine-cytidine kinase-like 1

Size: 548 amino acids; 61141 Da

Subunit: Interacts with RNF19B and EBV EBNA3

Subcellular location: Cytoplasm. Nucleus. Note=EBNA3 induces isoform 1 translocation to the nucleus, whereas it does

change isoform 3 location

Secondary accessions: B7Z8N2 Q5JWV0 Q70AQ5 Q8N524 Q9H3Z2

Alternative splicing: 4 isoforms: Q9NWZ5-1 Q9NWZ5-2 Q9NWZ5-3 Q9NWZ5-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for UCKL1: NX_Q9NWZ5

Post-translational modifications:

Ubiquitinated by RNF19B; which induces proteasomal degradation¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NWZ5

2 DME Specific Peptides for UCKL1 (Q9NWZ5)

DHPDAFD

NTVAIDL

UCKL1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001180308.1 NP_060329.2

ENSEMBL proteins:

ENSP00000346155 ENSP00000402994 ENSP00000404474 ENSP00000358908 ENSP00000358924

ENSP00000351546

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	Uscn Proteins for UCKL1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005783	endoplasmic reticulum	IDA	--

UCKL1 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for UCKL1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

UCKL1 for domains About GeneDecksing

2 InterPro domains/families:

IPR000764 Uridine_kinase

IPR006083 PRK/URK

Graphical View of Domain Structure for InterPro Entry Q9NWZ5

ProtoNet protein and cluster: Q9NWZ5

1 Blocks protein family: IPB000764 Uridine kinase signature

UniProtKB/Swiss-Prot: UCKL1_HUMAN, Q9NWZ5

Similarity: Belongs to the uridine kinase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: UCKL1_HUMAN, Q9NWZ5

Function: May contribute to UTP accumulation needed for blast transformation and proliferation

Catalytic activity: ATP + uridine = ADP + UMP

Catalytic activity: ATP + cytidine = ADP + CMP

Enzyme Number (IUBMB): EC 2.7.1.48¹ ²

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UCKL1

Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004849	uridine kinase activity	IEA	--
GO:0005515	protein binding	IPI	16709802
GO:0005524	ATP binding	IEA	--
GO:0016301	kinase activity	--	--
GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEA	--

UCKL1 for ontologies About GeneDecksing

3 GenomeRNAi human phenotypes for UCKL1:

G0/1 arrest

Increased G1 DNA content

Increased cell death HMECs cel

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Metabolism

Metabolic pathways

0.38

Purine metabolism

Pyrimidine metabolism

0.38

Glucuronidation

Drug metabolism - other enzymes

0.32

Pathway sources
See GeneCards unified pathways
Show all pathways

3 Kegg Pathways (Kegg details for UCKL1):

	Pyrimidine metabolism
	Drug metabolism - other enzymes
	Metabolic pathways

UniProtKB/Swiss-Prot: UCKL1_HUMAN, Q9NWZ5

Pathway: Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3

Pathway: Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1

UCKL1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for UCKL1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/38 Interacting proteins for UCKL1 (Q9NWZ5^{1, 3} ENSP00000346155⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 38)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RNF19B	Q6ZMZ0¹^,³, ENSP00000362555⁴	EBI-2466660,EBI-2466594 I2D: score=1 STRING: ENSP00000362555
EIF2B2	P49770³	I2D: score=2
GPT2	Q8TD30³	I2D: score=1
HSP90AA1	P07900³	I2D: score=1
HUWE1	Q7Z6Z7³	I2D: score=1

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0019048	virus-host interaction	IEA	--
GO:0044206	UMP salvage	IEA	--
GO:0044211	CTP salvage	IEA	--
GO:0044419	interspecies interaction between organisms	--	--

UCKL1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for UCKL1

10/22 HMDB Compounds for UCKL1 (see all 22) About this table

Compound	Synonyms	CAS #	PubMed Ids
ADP	adenosindiphosphorsaeure (see all 8)	58-64-0	--
Adenosine triphosphate	5'-(tetrahydrogen triphosphate) Adenosine (see all 24)	56-65-5	--
Cytidine	1-(b-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine (see all 20)	65-46-3	--
Cytidine monophosphate	5'-CMP (see all 14)	63-37-6	--
Deoxycytidine	1-(2-Deoxy-b-D-ribofuranosyl)cytosine (see all 15)	951-77-9	--
Deoxyuridine	1-(2-Deoxy-D-erythro-pentofuranosyl)uracil (see all 12)	951-78-0	--
Deoxyuridine triphosphate	2'-Deoxyuridine-5'-triphosphorate (see all 9)	1173-82-6	--
Guanosine diphosphate	5'-GDP (see all 10)	146-91-8	--
Guanosine triphosphate	5'-GTP (see all 10)	86-01-1	--
IDP	5'-IDP (see all 10)	86-04-4	--

4 DrugBank Compounds for UCKL1 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Alpha-Phosphoribosylpyrophosphoric Acid	--	13270-65-0	target	--	17139284 17016423 10592235
Guanosine-5'-Triphosphate	--	86-01-1	target	--	17139284 17016423 10592235
Uracil	--	66-22-8	target	--	17139284 17016423 10592235
Uridine-5'-Monophosphate	--	58-97-9	target	--	17139284 17016423 10592235

Search CenterWatch for drugs/clinical trials and news about UCKL1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for UCKL1 gene (2 alternative transcripts):

NM_001193379.1 NM_017859.3

Unigene Cluster for UCKL1:

Uridine-cytidine kinase 1-like 1

Hs.504998 [show with all ESTs]

Unigene Representative Sequence: AK128082

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000354216(uc010gkn.3 uc011abn.2 uc011abo.2) ENST00000430743

ENST00000492660 ENST00000418992 ENST00000483710 ENST00000369892 ENST00000369908(uc011abm.2)

ENST00000358711

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Additional cDNA sequence:

AJ605558.1 AK000524.1 AK128082.1 AK222559.1 AK223220.1 AK301602.1 AK303688.1 BC033078.1

22 DOTS entries:

DT.97817341 DT.95204026 DT.211623 DT.120803977 DT.75102038 DT.95173576 DT.95114287 DT.75109769

DT.209710 DT.120803978 DT.120803982 DT.100709734 DT.95173580 DT.100811435 DT.75118267 DT.100786530

DT.65287100 DT.95140900 DT.209709 DT.95256609 DT.120804018 DT.91741721

24/172 AceView cDNA sequences (see all 172):

BE552310 BQ637053 AI738474 BE304354 AI364501 AA516005 AI953030 BQ640057

CR594251 BI772135 BM021921 BE501787 BU684988 BX442579 BE501778 BM758850

F27242 AI654629 BI963021 AW328301 CF127698 BM668439 CB163966 BM702108

GeneLoc Exon Structure

5/17 Alternative Splicing Database (ASD) splice patterns (SP) for UCKL1 (see all 17) About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4a	·	4b	·	4c	^	5a	·	5b	·	5c	·	5d	^	6	^	7a	·	7b	·	7c	·	7d	·	7e	·	7f	^	8a	·	8b	^	9a	·	9b	^	10	^	11a	·	11b	·
SP1:							-		-														-		-		-		-																				-		-
SP2:																																																	-		-
SP3:							-		-														-		-		-		-
SP4:
SP5:							-		-														-		-		-

ExUns:	11c	·	11d	·	11e	^	12	^	13	^	14	^	15a	·	15b	^	16	^	17
SP1:	-
SP2:	-				-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for UCKL1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

UCKL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCAGAGATGG

About this image
See UCKL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UCKL1

SOURCE GeneReport for Unigene cluster: Hs.504998

UniProtKB/Swiss-Prot: UCKL1_HUMAN, Q9NWZ5

Tissue specificity: Ubiquitous

SABiosciences Custom PCR Arrays for UCKL1

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UCKL1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the last universal common ancestor (LUCA).

Orthologs for UCKL1 gene from 10/31 species (see all 31) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Uckl1^{1 , 5}	uridine-cytidine kinase 1-like 1^{1, 5}	85.83(n)¹ 94.89(a)¹		2 (103.66 cM)⁵ 68556¹ NM_026765.3¹ NP_081041.2¹ 181569149⁵
chicken (Gallus gallus)	Aves	UCKL1¹	uridine-cytidine kinase 1-like 1	82.97(n) 92.14(a)		771616 XM_001234873.2 XP_001234874.1
lizard (Anolis carolinensis)	Reptilia	UCKL1⁶ UPRT⁶	--	81(a) 34(a)	1 ↔ 1 possible ortholog	GL344220.1(39718-53248) GL343825.1(74337-84296)
African clawed frog (Xenopus laevis)	Amphibia	Xl.16539²	Xenopus laevis transcribed sequence with moderate similarity more	78.73(n)		BU915533.1
zebrafish (Danio rerio)	Actinopterygii	57092043²	--	77.96(n)		57092043
fruit fly (Drosophila melanogaster)	Insecta	l(2)k01209⁶	lethal (2) k01209	50(a)	1 ↔ 1	2R(13307938-13313192)
worm (Caenorhabditis elegans)	Secernentea	F19B6.1⁶	Uridine kinase	47(a)	1 ↔ 1	IV(12330962-12336018)
thale cress (Arabidopsis thaliana)	eudicotyledons	UKL5¹	putative uracil phosphoribosyltransferase	51.97(n) 46.7(a)		822365 NM_113659.1 NP_189380.1
rice (Oryza sativa)	Liliopsida	-- --	phosphoribulokinase/Uridine kinase family protein,... phosphoribulokinase/Uridine kinase family protein,...	16(a) 14(a)	possible ortholog possible ortholog	4(29922079-29923760) 2(28695935-28698540)
E. coli (Escherichia coli)	Gamma proteobacteria	udk⁶	uridine/cytidine kinase	37(a)	possible ortholog	Chromosome(2140331-2140972)

ENSEMBL Gene Tree for UCKL1 (if available)
TreeFam Gene Tree for UCKL1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for UCKL1 gene

UCK2² UCK1²

4 SIMAP similar genes for UCKL1 using alignment to 4 protein entries: UCKL1_HUMAN (see all proteins):

UCK2 UCK1 UPRT RP11-311P8.3

UCKL1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs144556639^1,2	C,	--	62570832(+)	`ACCCT-/CCCCCC`	2	--	int¹		0	--	--	--	--
rs34445443^1,2	C	--	62570836(+)	`CCCTCC/-CCCCC`	2	--	int¹		1		NA	2
rs202063488^1,2		--	62570842(+)	`CCCCC-/CGCCCAA`	2	--	int¹		0	--	--	--	--
rs76828583^1,2	F,	--	62570844(+)	`CCCCCC/GCAACT`	2	--	int¹		1		WA	118
rs6011233^1,2	C,F,H	--	62571020(+)	`GCCCAG/TTTCTA`	2	--	int¹		4		NS NA	506
rs147406596^1,2		--	62571157(+)	`CACCTC/TTCCTG`	2	--	int¹		0	--	--	--	--
rs201418724^1,2		--	62571290(+)	`GAGGCA/CGGAGG`	2	--	ut3¹		0	--	--	--	--
rs185510784^1,2	C,	--	62571298(+)	`AGGAGG/TGTGGT`	2	--	ut3¹		0	--	--	--	--
rs201832808^1,2		--	62571349(+)	`CACTTC/TCTCCT`	4	K E	mis¹		0	--	--	--	--
rs35264801^1,2	C,F	--	62571418(+)	`GGGGGG/-TCCAG`	2	--	int¹		2		NA	4

HapMap Linkage Disequilibrium report for UCKL1 (62571182 - 62587800 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for UCKL1
1 CNV: 2252
1 Indel: 73575

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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UCKL1 for disorders           About GeneDecksing

OMIM gene information: 610866    OMIM disorders: --

1 disease for UCKL1:    About MalaCards

alcoholism

Export disorders for UCKL1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for UCKL1 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with UCKL1)

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NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase. (PubMed id 16709802)^{1, 2, 9} Fortier J.M. and Kornbluth J. (2006)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{1, 2} Beausoleil S.A.... Gygi S.P. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase. (PubMed id 12199906)^{1, 2} Kashuba E.... Szekely L. (2002)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
Downregulation of uridine-cytidine kinase like-1 decr eases proliferation and enhances tumor susceptibility to lysis by apoptotic age nts and natural killer cells. (PubMed id 19653100)^{1, 9} Ambrose E.C. and Kornbluth J. (2009)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54963	HGNC: 15938	AceView: UCKL1	Ensembl:ENSG00000198276	euGenes: HUgn54963
ECgene: UCKL1	Kegg: 54963	H-InvDB: UCKL1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for UCKL1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for UCKL1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for UCKL1 gene:
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uridine-cytidine kinase 1-like 1

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uridine-cytidine kinase 1-like 1

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