TPCN2 Gene
protein-coding GIFtS: 53
GCID: GC11P068816
|
|
two pore segment channel 2
| |
Aliases
for TPCN2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Two Pore Segment Channel 21 2 | | TPC21 2 3 5 | | Voltage-Dependent Calcium Channel Protein TPC22 3 | | SHEP102 5 | | Two Pore Calcium Channel Protein 22 | | Two-Pore Calcium Channel Protein 22 |
Export aliases for TPCN2 gene to outside databasesPrevious GC identifers: GC11P069066 GC11P068591 GC11P068572 GC11P065155 |
Summaries
for TPCN2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TPCN2:
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The proteinlocalizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calciumion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver andkidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hairpigmentation.(provided by RefSeq, Dec 2009)
UniProtKB/Swiss-Prot: TPC2_HUMAN, Q8NHX9Function: Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the majorvoltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction
Gene Wiki entry for TPCN2
|
Genomic Views
for TPCN2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TPCN2 gene promoter:
MAZR AML1a CUTL1 NF-kappaB Arnt Roaz Ik-2 NF-kappaB1 Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TPCN2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPCN2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13.3 Ensembl cytogenetic band: 11q13.3 HGNC cytogenetic band: 11q13.1TPCN2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P068816: view genomic region
(about GC identifiers)
Start:
|
68,816,350 bp from pter |
End:
|
68,858,072 bp from pter |
Size:
|
41,723 bases |
Orientation:
|
plus strand |
|
Proteins
for TPCN2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TPC2_HUMAN, Q8NHX9 (See
protein sequence)Recommended Name: Two pore calcium channel protein 2 Size: 752 amino acids; 85243 Da
Subunit: Homodimer (By similarity). Interacts with LRRK2
Subcellular location: Lysosome membrane; Multi-pass membrane protein (By similarity). Note=Only the acidic lysosomalfraction is sensitive to NAADP (By similarity)
Secondary accessions: Q9NT82Explore the universe of human proteins at neXtProt for TPCN2: NX_Q8NHX9
Post-translational modifications:
N-glycosylated (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NHX9
TPCN2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_620714.2
ENSEMBL proteins: ENSP00000438724 ENSP00000294309 ENSP00000445551 Reactome Protein details: Q8NHX9
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
TPCN2 for ontologies About GeneDecksing
TPCN2 Antibody Products:
Assay Products for TPCN2: |
Protein
Domains /
Families
for TPCN2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TPCN2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8NHX9ProtoNet protein and cluster: Q8NHX9 UniProtKB/Swiss-Prot: TPC2_HUMAN, Q8NHX9Domain: Each of the two internal repeats contains five hydrophobic transmembrane segments (S1, S2, S3, S5, S6) and onepositively charged transmembrane segment (S4). S4 segments probably represent the voltage-sensor and are characterizedby a series of positively charged amino acids at every third position (By similarity)Similarity: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily |
Function
for TPCN2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TPC2_HUMAN, Q8NHX9Function: Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the majorvoltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TPCN2 (NM_139075) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TPCN2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPCN2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPCN2 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
TPCN2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for TPCN2:
Animal Models:
Mouse knock-outs for TPCN2: Tpcn2tm1Lex Tpcn2tm1.1Dren
6 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Tpcn2):
TPCN2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TPCN2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ion channel transport | | | 2 | Pancreatic secretion | | | 3 | SLC-mediated transmembrane transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for TPCN2
1 
Kegg Pathway (Kegg details for TPCN2):
TPCN2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TPCN2
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for TPCN2 (Q8NHX91 ENSP000002943094) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006874 | cellular calcium ion homeostasis |
IDA | 19387438 | | GO:0006939 | smooth muscle contraction |
ISS | -- | | GO:0051209 | release of sequestered calcium ion into cytosol |
IEA | -- | | GO:0051925 | regulation of calcium ion transport via voltage-gated calcium channel activity |
-- | -- |
TPCN2 for ontologies About GeneDecksing
|
Drugs & Compounds
for TPCN2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TPCN2
1 HMDB Compound for TPCN2 About this table
Search CenterWatch for drugs/clinical trials and news about TPCN2 / TPC2
|
Transcripts
for TPCN2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TPCN2 gene: NM_139075.3 Unigene Cluster for TPCN2: Two pore segment channel 2 Hs.131851 [show with all ESTs]Unigene Representative Sequence: NM_1390756 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000539166 ENST00000294309(uc009ysk.1 uc010rqg.1) ENST00000535009(uc001oor.2)
ENST00000542467 ENST00000534832 ENST00000442692(uc001oos.2 uc021qmo.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TPCN2 (NM_139075) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TPCN2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPCN2 |
Additional cDNA sequence: AK023366.1 AK124882.1 AK298919.1 AL137479.1 AY029200.1 BC063008.1 BC064339.1 12 DOTS entries: DT.40232060 DT.100754345 DT.408015 DT.100754343 DT.97816364 DT.102830420 DT.95259567 DT.100714388 DT.121630714 DT.100734990 DT.102830419 DT.92060092 24/115 AceView cDNA sequences (see all 115): CK300944 BF476556 BQ219203 BM728630 AA574158 BQ186415 BM747712 AI636300 CD245584 BQ017510 AI632290 AI695882 AI632451 BU681181 AI825151 BF059396 AL137479 NM_139075 CA425690 BU176458 BI490907 AI700323 AW613529 BM673442
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TPCN2 (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · |
|---|
|
| SP1: | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | - | | | | | | | | - | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 17b | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25a | · | 25b |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | - | | | | | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for TPCN2
|
Expression
for TPCN2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TPCN2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGCTGAGGG
About this image
See TPCN2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TPCN2
SOURCE GeneReport for Unigene cluster: Hs.131851
UniProtKB/Swiss-Prot: TPC2_HUMAN, Q8NHX9Tissue specificity: Widely expressed. Expressed at high level in liver and kidney
SABiosciences Custom PCR Arrays for TPCN2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TPCN2
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPCN2 |
Orthologs
for TPCN2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TPCN2 gene from 3/16 species (see all 16) About this table
ENSEMBL Gene Tree for TPCN2 (if available)
TreeFam Gene Tree for TPCN2 (if available) |
Paralogs
for TPCN2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TPCN2 gene
- TPCN12
TPCN2 for paralogs About GeneDecksing
|
Genomic Variants
for TPCN2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: TPC2_HUMAN, Q8NHX9Polymorphism: Genetic variants in TPCN2 define the skin/hair/eye pigmentation variation locus 10 (SHEP10) [MIM:612267].Hair, eye and skin pigmentation are among the most visible examples of human phenotypic variation, with a broad normalrange that is subject to substantial geographic stratification. In the case of skin, individuals tend to have lighterpigmentation with increasing distance from the equator. By contrast, the majority of variation in human eye and haircolor is found among individuals of European ancestry, with most other human populations fixed for brown eyes andblack hair
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TPCN2 (68816350 - 68858072 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for TPCN2
3 CNVs: 71345 29915 65985
3 Indels: 75689 24797 85832
Human Gene Mutation Database (HGMD): TPCN2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TPCN2 |
|
Disorders
/ Diseases
for TPCN2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TPCN2 for disorders About GeneDecksing
OMIM gene information: 612163
OMIM disorders: 612267
2  diseases for TPCN2: About MalaCardsskin/hair/eye pigmentation 10, blond/brown hair pancreatitis
Human Genome Epidemiology (HuGE) Navigator: TPCN2 (1 document)
Export disorders for TPCN2 gene to outside databases
|
Publications
for TPCN2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TPCN2 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with TPCN2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Essential requirement for two-pore channel 1 in NAADP -mediated calcium signaling. (PubMed id 19620632)1, 2, 9 Brailoiu E....Patel S. (2009)
- NAADP mobilizes calcium from acidic organelles throug h two-pore channels. (PubMed id 19387438)1, 2 Calcraft P.J....Zhu M.X. (2009)
- Two newly identified genetic determinants of pigmentation in Europeans. (PubMed id 18488028)1, 2 Sulem P....Stefansson K. (2008)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)1, 2 Taylor T.D....Sakaki Y. (2006)
- International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels. (PubMed id 16382101)1, 3 Clapham D.E. and Garbers D.L. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Leucine-rich repeat kinase 2 regulates autophagy through a calcium- dependent pathway involving NAADP. (PubMed id 22012985)2 Gomez-Suaga P.... Hilfiker S. (2012)
- Two-pore channel 2 (TPC2) modulates store-operated Ca( 2+) entry. (PubMed id 23077736)1 Lopez J....Rosado J.A. (2012)
- Web-based, participant-driven studies yield novel gen etic associations for common traits. (PubMed id 20585627)1 Eriksson N....Mountain J. (2010)
- TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+. (PubMed id 20720007)1 Pitt S.J....Sitsapesan R. (2010)
|
External Searches for TPCN2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TPCN2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TPCN2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TPCN2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TPCN2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TPCN2 gene:
Search GeneIP for patents involving TPCN2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TPCN2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for TPCN2 | | OriGene shRNA RFP for TPCN2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TPCN2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TPCN2 | | | OriGene Protein Over-expression Lysate for TPCN2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TPCN2 | | OriGene 3'-UTR Clone for TPCN2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TPCN2 | | OriGene Custom Protein Services for TPCN2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TPCN2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TPCN2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPCN2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TPCN2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TPCN2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TPCN2 |
| |
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| | | | Search Tocris compounds for TPCN2 |
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 | | | TPCN2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPCN2 |
|  |  |  | | | | Search ThermoFisher Antibodies for TPCN2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPCN2 |
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