TPCN1 Gene
protein-coding GIFtS: 51
GCID: GC12P113660
|
|
two pore segment channel 1
| |
Aliases
for TPCN1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Two Pore Segment Channel 11 2 | | FLJ206121 | | TPC11 2 3 5 | | Two Pore Calcium Channel Protein 12 | | KIAA11691 3 5 | | Two-Pore Channel 12 | | Voltage-Dependent Calcium Channel Protein TPC12 3 | | Two-Pore Segment Channel 12 |
Export aliases for TPCN1 gene to outside databasesPrevious GC identifers: GC12P113441 GC12P112071 GC12P112121 GC12P110671 |
Summaries
for TPCN1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TPCN1:
Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6.TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 (PubMed10753632)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: TPC1_HUMAN, Q9ULQ1Function: Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the majorvoltage-gated Ca(2+) channels (VDCC) across the lysosomal and endosomal membrane
Gene Wiki entry for TPCN1
|
Genomic Views
for TPCN1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009775.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TPCN1 gene promoter:
NF-YB CBF-B CBF-A NF-YA ARP-1 CP1C CP1A LUN-1 NF-Y CBF-C
Other transcription factors
Search SABiosciences Chromatin IP Primers for TPCN1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPCN1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.13 Ensembl cytogenetic band: 12q24.13 HGNC cytogenetic band: 12q24.21TPCN1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P113660: view genomic region
(about GC identifiers)
Start:
|
113,658,855 bp from pter |
End:
|
113,736,390 bp from pter |
Size:
|
77,536 bases |
Orientation:
|
plus strand |
|
Proteins
for TPCN1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TPC1_HUMAN, Q9ULQ1 (See
protein sequence)Recommended Name: Two pore calcium channel protein 1 Size: 816 amino acids; 94147 Da
Subunit: Dimer (Potential)
Subcellular location: Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein
Sequence caution: Sequence=AK057414; Type=Frameshift; Positions=273; Sequence=BAA86483.2; Type=Erroneous initiation;Note=Translation N-terminally shortened;
Secondary accessions: A7E258 Q86XS9 Q8NC20Alternative splicing: 3 isoforms: Q9ULQ1-1 Q9ULQ1-2 Q9ULQ1-3 Explore the universe of human proteins at neXtProt for TPCN1: NX_Q9ULQ1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9ULQ1
TPCN1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001137291.1 NP_060371.2
ENSEMBL proteins: ENSP00000447806 ENSP00000449560 ENSP00000447569 ENSP00000447073 ENSP00000447263 ENSP00000447181 ENSP00000335300 ENSP00000449944 ENSP00000448083 ENSP00000448704 ENSP00000376350 ENSP00000446767 ENSP00000448561 ENSP00000449564 ENSP00000448010 ENSP00000438125 Reactome Protein details: Q9ULQ1
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
TPCN1 for ontologies About GeneDecksing
TPCN1 Antibody Products:
Assay Products for TPCN1: |
Protein
Domains /
Families
for TPCN1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TPCN1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9ULQ1ProtoNet protein and cluster: Q9ULQ1 UniProtKB/Swiss-Prot: TPC1_HUMAN, Q9ULQ1Domain: Each of the two internal repeats contains five hydrophobic transmembrane segments (S1, S2, S3, S5, S6) and onepositively charged transmembrane segment (S4). S4 segments probably represent the voltage-sensor and are characterizedby a series of positively charged amino acids at every third position (By similarity)Similarity: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily |
Function
for TPCN1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TPC1_HUMAN, Q9ULQ1Function: Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the majorvoltage-gated Ca(2+) channels (VDCC) across the lysosomal and endosomal membrane
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TPCN1 (NM_017901) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TPCN1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPCN1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPCN1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
TPCN1 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Tpcn1tm1.1Dren for TPCN1
3 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Tpcn1):
TPCN1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TPCN1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ion channel transport | | | 2 | SLC-mediated transmembrane transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for TPCN1
TPCN1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TPCN1
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for TPCN1 (Q9ULQ11 ENSP000003763504) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for TPCN1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TPCN1
1 HMDB Compound for TPCN1 About this table
Search CenterWatch for drugs/clinical trials and news about TPCN1 / TPC1
|
Transcripts
for TPCN1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TPCN1 gene (2 alternative transcripts): NM_001143819.1 NM_017901.4 Unigene Cluster for TPCN1: Two pore segment channel 1 Hs.524763 [show with all ESTs]Unigene Representative Sequence: NM_00114381918/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23): ENST00000552642 ENST00000547275 ENST00000552985 ENST00000550873 ENST00000551096
ENST00000551099 ENST00000335509(uc001tuw.3 uc010syu.2) ENST00000552897
ENST00000550785(uc001tux.3) ENST00000549279 ENST00000552077 ENST00000392569
ENST00000552542 ENST00000428632(uc010syt.1) ENST00000548465 ENST00000546781
ENST00000551127 ENST00000546503
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): TPCN1 (NM_017901) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TPCN1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPCN1 |
Additional cDNA sequence: AB032995.2 AK000619.1 AK025838.1 AK057414.1 AK093490.1 AK295022.1 AK296268.1 AY083666.1 BC007419.2 BC068001.1 BC069234.1 BC110885.1 BC136795.1 BC136796.1 BC150203.1 BC152423.1 16 DOTS entries: DT.95283828 DT.216244 DT.100816008 DT.95215830 DT.91920798 DT.121170051 DT.92003407 DT.92439571 DT.121169983 DT.40311973 DT.92439573 DT.95100794 DT.95303166 DT.101960618 DT.40259869 DT.99949916 24/335 AceView cDNA sequences (see all 335): BQ681979 AI302315 CR599771 BQ948574 BU146988 BX283980 AW271180 H50290 BX281034 AY083666 BG756072 BE938213 BF434781 R88552 BQ679647 AI631823 BM827150 AW505119 BU687277 H18210 AW589639 AK075071 AI423506 CR614337
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for TPCN1 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 20a | · | 20b | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 |
|---|
|
| SP1: | | | - | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for TPCN1
|
Expression
for TPCN1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TPCN1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGGACAATCA
About this image
See TPCN1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TPCN1
SOURCE GeneReport for Unigene cluster: Hs.524763
UniProtKB/Swiss-Prot: TPC1_HUMAN, Q9ULQ1Tissue specificity: Highest expression found in the heart and kidney, and lowest expression found in the spleen
SABiosciences Custom PCR Arrays for TPCN1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TPCN1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPCN1 |
Orthologs
for TPCN1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TPCN1 gene from 7/18 species (see all 18) About this table
ENSEMBL Gene Tree for TPCN1 (if available)
TreeFam Gene Tree for TPCN1 (if available) |
Paralogs
for TPCN1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TPCN1 gene
- TPCN22
15 SIMAP similar genes for TPCN1 using alignment to 14 protein entries: TPC1_HUMAN (see all proteins):SCN9A SCN4A SCN5A CACNA1H SCN11A SCN8A
SCN3A CACNA1F SCN1A SCN2A SCN2A2 SCN7A
CACNA1B CACNA1E CACNA1A
TPCN1 for paralogs About GeneDecksing
|
Genomic Variants
for TPCN1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TPCN1 (113658855 - 113736390 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for TPCN1
2 Indels: 61279 44971 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TPCN1 |
|
Disorders
/ Diseases
for TPCN1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TPCN1 for disorders About GeneDecksing
OMIM gene information: 609666
OMIM disorders: --
3  diseases for TPCN1: About MalaCardsstomatitis thyroid cancer thyroiditis
1 disease from the University of Copenhagen DISEASES database for TPCN1:Thyroid cancer Export disorders for TPCN1 gene to outside databases
|
Publications
for TPCN1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TPCN1 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with TPCN1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2, 3 Hirosawa M.... Ohara O. (1999)
- Essential requirement for two-pore channel 1 in NAADP -mediated calcium signaling. (PubMed id 19620632)1, 2, 9 Brailoiu E....Patel S. (2009)
- NAADP mobilizes calcium from acidic organelles throug h two-pore channels. (PubMed id 19387438)1, 2 Calcraft P.J....Zhu M.X. (2009)
- International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels. (PubMed id 16382101)1, 3 Clapham D.E. and Garbers D.L. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels. (PubMed id 10753632)1, 3 Ishibashi K....Imai M. (2000)
- Regulation of a proteinaceous elicitor-induced Ca2+ in flux and production of phytoalexins by a putative voltage-gated cation channel, OsTPC1, in cultured rice cells. (PubMed id 22270358)1 Hamada H....Kuchitsu K. (2012)
- Membrane potential regulates nicotinic acid adenine di nucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1. (PubMed id 22500018)1 Rybalchenko V....Muallem S. (2012)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
|
External Searches for TPCN1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TPCN1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TPCN1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing TPCN1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TPCN1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TPCN1 gene:
Search GeneIP for patents involving TPCN1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TPCN1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TPCN1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TPCN1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TPCN1 | | | OriGene Protein Over-expression Lysate for TPCN1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for TPCN1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPCN1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TPCN1 | | OriGene Custom Protein Services for TPCN1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TPCN1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TPCN1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPCN1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TPCN1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TPCN1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TPCN1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for TPCN1 |
| |  |  |  |  | | | | |
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 | | | TPCN1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPCN1 |
|  |  |  | | | | Search ThermoFisher Antibodies for TPCN1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPCN1 |
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