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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TM4SF1 Gene

protein-coding   GIFtS: 53
GCID: GC03M149086

transmembrane 4 L six family member 1

(Previous name: transmembrane 4 superfamily member 1 )
(Previous symbol: M3S1)
 Explore 7 diseases affiliated with
TM4SF1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TM4SF1    

Aliases
for TM4SF1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Transmembrane 4 L Six Family Member 11 2     Membrane Component Chromosome 3 Surface Marker 12 3
M3S11 2 3 5     Tumor-Associated Antigen L62 3
TAAL62 3 5     H-L62
L61 2     Membrane Component, Chromosome 3, Surface Marker 12
Transmembrane 4 Superfamily Member 11 2     Transmembrane 4 L6 Family Member 12

External Ids:    HGNC: 118531   Entrez Gene: 40712   Ensembl: ENSG000001699087   OMIM: 1911555   UniProtKB: P304083   

Export aliases for TM4SF1 gene to outside databases

Previous GC identifers: GC03U990049 GC03M149971 GC03M150368 GC03M150407 GC03M150569 GC03M146458


Summaries
for TM4SF1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TM4SF1:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family.
Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains.
The proteins mediate signal transduction events that play a role in the regulation of cell development, activation,
growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas.
(provided by RefSeq, Jul 2008)

Gene Wiki entry for TM4SF1


Genomic Views
for TM4SF1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TM4SF1 gene promoter:
         NF-1   HNF-1A   SRY   CBF-B   CBF-A   FOXO4   HNF-1   c-Myb   c-Jun   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TM4SF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TM4SF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TM4SF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21-q25   Ensembl cytogenetic band:  3q25.1   HGNC cytogenetic band: 3q21-q25

TM4SF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TM4SF1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M149086:  view genomic region     (about GC identifiers)

Start:
 149,086,805 bp from pter      End:
 149,095,652 bp from pter
Size:
 8,848 bases      Orientation:
 minus strand

Proteins
for TM4SF1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: T4S1_HUMAN, P30408 (See protein sequence)
Recommended Name: Transmembrane 4 L6 family member 1  
Size: 202 amino acids; 21632 Da
Subunit: Present in high molecular weight complexes in tumor cells
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: Q6IB51

Explore the universe of human proteins at neXtProt for TM4SF1: NX_P30408

TM4SF1 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_055035.1  
ENSEMBL proteins: 
 ENSP00000304277   ENSP00000417084   ENSP00000419426   ENSP00000418025  

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Uscn Proteins for TM4SF1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005887integral to plasma membrane IDA7510285
GO:0016021integral to membrane ----


TM4SF1 for ontologies           About GeneDecksing



TM4SF1 Antibody Products: 
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Uscn ELISAs and CLIAs for TM4SF1

Protein Domains /
Families
for TM4SF1 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
TM4SF1 for domains           About GeneDecksing

1 InterPro domain/family:
 IPR008661 L6_membrane

Graphical View of Domain Structure for InterPro Entry P30408

ProtoNet protein and cluster: P30408

1 Blocks protein family: IPB008661 L6 membrane

UniProtKB/Swiss-Prot: T4S1_HUMAN, P30408
Similarity: Belongs to the L6 tetraspanin family


Function
for TM4SF1 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Function Summary:
     Genatlas biochemistry entry for TM4SF1:
transmembrane 4 superfamily member 1,membrane component chromosome 3,cell surface marker 1

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TM4SF1
8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate TM4SF1 (see all 17):
hsa-miR-3607-3p hsa-miR-520d-5p hsa-miR-300 hsa-miR-200a hsa-miR-3916 hsa-miR-3125 hsa-miR-141 hsa-miR-3153
SwitchGear 3'UTR luciferase reporter plasmid: TM4SF1 3' UTR sequence
Inhib. RNA
Products:    		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TM4SF1 (see all 7)
OriGene shRNA RFP: TM4SF1
OriGene siRNA: TM4SF1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TM4SF1

Gene Editing
Products:		DNA2.0 Custom Protein Engineering Service for TM4SF1

Clone
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OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TM4SF1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TM4SF1 (see all 2)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TM4SF1 

Cell Line
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Search LifeMap BioReagents cell lines for TM4SF1

In Situ Assay
Products:   
 		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM4SF1

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--


TM4SF1 for ontologies           About GeneDecksing



Pathways & Interactions
for TM4SF1 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TM4SF1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/61 Interacting proteins for TM4SF1 (P304082, 3 ENSP000003042774) via UniProtKB, MINT, STRING, and/or I2D (see all 61)
InteractantInteraction Details
GeneCardExternal ID(s)
DDR1Q083452, 3MINT-63643 I2D: score=5 
DNAJA1P316892, 3MINT-63642 I2D: score=5 
HSPA8P111422, 3MINT-63447 I2D: score=5 
ANPEPP151443, ENSP000003000604I2D: score=1 STRING: ENSP00000300060
SDCBP2Q9H1903, ENSP000003429354I2D: score=1 STRING: ENSP00000342935
About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008150biological_process ND--


TM4SF1 for ontologies           About GeneDecksing



Drugs & Compounds
for TM4SF1 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TM4SF1
Search CenterWatch for drugs/clinical trials and news about TM4SF1 / T4S1 

Transcripts
for TM4SF1 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
REFSEQ mRNAs for TM4SF1 gene: 
NM_014220.2  

Unigene Cluster for TM4SF1:

Transmembrane 4 L six family member 1
Hs.740377  [show with all ESTs]
Unigene Representative Sequence: AL832780
4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000305366(uc003exb.1) ENST00000472441(uc003exc.1) ENST00000493348
ENST00000493298

miRNA
Products:     		 OriGene 3'-UTR Clone: TM4SF1
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TM4SF1
8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate TM4SF1 (see all 17):
hsa-miR-3607-3p hsa-miR-520d-5p hsa-miR-300 hsa-miR-200a hsa-miR-3916 hsa-miR-3125 hsa-miR-141 hsa-miR-3153
SwitchGear 3'UTR luciferase reporter plasmid: TM4SF1 3' UTR sequence
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TM4SF1 (see all 7)
OriGene shRNA RFP: TM4SF1
OriGene siRNA: TM4SF1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TM4SF1
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TM4SF1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: TM4SF1 (NM_014220)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TM4SF1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TM4SF1 
Primer
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Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TM4SF1
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TM4SF1
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TM4SF1

Additional cDNA sequence: 

AK023364.1 AK093829.1 AK130073.1 AK130271.1 AL832780.1 BC008442.1 BC010166.2 BC034145.1 
CR456953.1 X75684.1 

24/29 DOTS entries (see all 29):

DT.97857021  DT.70102773  DT.100884797  DT.91991467  DT.91981673  DT.75100304  DT.120913546  DT.100884803 
DT.100884802  DT.100884805  DT.100884809  DT.91908111  DT.100884796  DT.95373587  DT.120913533  DT.120913576 
DT.85101176  DT.97864631  DT.100045040  DT.100677256  DT.100710264  DT.102825807  DT.120913571  DT.91774100 

24/1004 AceView cDNA sequences (see all 1004):

BU157977 AW675302 BX403739 CD678204 BE773473 AI990827 CF128883 AI859160 
BM460535 BM827306 AI769516 AI760128 AA136658 CB122167 CA416391 AI985583 
BM826767 CB158632 BM977533 AA343532 AI621320 AA903050 AI950693 BP336498 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for TM4SF1    About this scheme

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b · 5c
SP1:                                            -                                       
SP2:                                -     -     -                                       
SP3:                                      -     -     -                                 
SP4:                                            -                                       
SP5:                                                                                    


ECgene alternative splicing isoforms for TM4SF1

Expression
for TM4SF1 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TM4SF1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGACGAGTG

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image

TM4SF1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
9 LifeMap In Vivo Development Anatomical Compartments/Cells 
Tissue Anatomical Compartment CellCategory (developmental path)
LiverLiver LobulePeriportal HepatocytesLiver
OvaryOvigerous CordOvarian Somatic CellsOvary
Spinal CordSpinal Floor PlateFloor Plate Cells Neural Ectoderm
BoneZeugopod Epiphyseal EndBone
BrainMedulla OblongataBrain
HeartDorsal AortaHeart
KidneyS-shaped BodyKidney
Neural TubeMetencephalonNeural Tube
Spinal CordSpinal Floor PlateSpinal Cord
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization
Stem Cell Differentiation: 2 LifeMap Cells 
NameCategory
PureStem™ progenitor F15 (Embryonic Progenitor Cell)
Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)

See TM4SF1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TM4SF1

SOURCE GeneReport for Unigene cluster: Hs.740377

UniProtKB/Swiss-Prot: T4S1_HUMAN, P30408
Tissue specificity: Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal
cells, endothelial cells in particular

    SABiosciences Custom PCR Arrays for TM4SF1
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In Situ
Assay Products: 
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Orthologs
for TM4SF1 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of chordates.

Orthologs for TM4SF1 gene from 2/8 species (see all 8)    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
chicken
(Gallus gallus)		 Aves TM4SF11 transmembrane 4 L six family member 1 63.2(n)
64.36(a)		   425046  XM_422848.3  XP_422848.2 
African clawed frog
(Xenopus laevis)		 Amphibia Xl.187172 Xenopus laevis transcribed sequence with moderate similarity more 75.98(n)    BX851640.1 


ENSEMBL Gene Tree for TM4SF1 (if available)
TreeFam Gene Tree for TM4SF1 (if available) 

Paralogs
for TM4SF1 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for TM4SF1 gene
TM4SF52  TM4SF42  TM4SF192  TM4SF182  
4 SIMAP similar genes for TM4SF1 using alignment to 5 protein entries:     T4S1_HUMAN (see all proteins):
TM4SF4    TM4SF18    TM4SF5    TM4SF19

TM4SF1 for paralogs           About GeneDecksing



Genomic Variants
for TM4SF1 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/211 NCBI SNPs in TM4SF1 are shown (see all 211)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 3 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs1472413711,2
--149086463(+) TTTCTA/GTAGAA 1 -- ds50010--------
rs1900811981,2
--149086629(+) CAATGA/GCAATT 1 -- ds50010--------
rs355256971,2
C,F,--149086665(+) GAAAGA/TGGATG 1 -- ds50017Minor allele frequency- T:0.18NA WA EA 366
rs1120392131,2
--149086715(+) AGCAAT/CAGGGG 1 -- ds50012Minor allele frequency- C:0.04CSA WA 120
rs1826602631,2
--149086722(+) GGGGCA/CACATA 1 -- ds50010--------
rs768060881,2
C,--149086749(+) AAAAA-/AAGGGGGG 1 -- ds50010--------
rs1399514171,2
C,--149086750(+) AAAAA-/AGGGGGG 1 -- ds50010--------
rs2001205951,2
C--149086750(+) AAAAAA/GGGGGG 1 -- ds50010--------
rs113288801,2
C,F--149086751(+) GGGGGG/-AGAAA 1 -- ds50012Minor allele frequency- -:0.50NA 4
rs1393691721,2
--149086791(+) AATGAA/CACTAA 1 -- ds50010--------

HapMap Linkage Disequilibrium report for TM4SF1 (149086805 - 149095652 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for TM4SF1: --

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TM4SF1
DNA2.0 Custom Variant and Variant Library Synthesis for TM4SF1

Disorders / Diseases
for TM4SF1 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
TM4SF1 for disorders           About GeneDecksing

OMIM gene information: 191155    OMIM disorders: --

7 diseases for TM4SF1:    About MalaCards
carcinoma    ovarian carcinoma    gastric cancer    lung cancer
prostate cancer    prostatitis    immunodeficiency


Export disorders for TM4SF1 gene to outside databases

Publications
for TM4SF1 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for TM4SF1 gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with TM4SF1)		    Utopia: connect your pdf to the dynamic
world of online information

  1. Cloning and expression of the tumor-associated antigen L6. (PubMed id 1565644)1, 2, 3 Marken J.S.... Aruffo A. (1992)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody. (PubMed id 7510285)1, 2 Marken J.S.... Aruffo A. (1994)
  4. Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins. (PubMed id 8168850)1, 9 Virtaneva K.I....Schroder J.P. (1994)
  5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
  6. TM4SF1: a tetraspanin-like protein necessary for nano podia formation and endothelial cell migration. (PubMed id 21626280)1 Zukauskas A....Jaminet S.C. (2011)
  7. Genes associated with prognosis after surgery for mal ignant pleural mesothelioma promote tumor cell survival in vitro. (PubMed id 21569526)1 Gordon G.J....Sugarbaker D.J. (2011)
  8. Combined omics analysis identifies transmembrane 4 L6 family member 1 as a surface protein marker specific to human mesenchymal stem cells. (PubMed id 20486778)1 Bae S....Kim H. (2011)
  9. TM4SF1, a novel primary androgen receptor target gene over-expressed in human prostate cancer and involved in cell migration. (PubMed id 21656834)1 Allioli N....Samarut J. (2011)
  10. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)

External Searches for TM4SF1 gene

(in PubMed, OMIM, and NCBI Bookshelf)
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Genome Databases showing TM4SF1 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 4071 HGNC: 11853 AceView: TM4SF1 Ensembl:ENSG00000169908 euGenes: HUgn4071
ECgene: TM4SF1 H-InvDB: TM4SF1

Other Databases showing TM4SF1 gene

(According to HUGE)
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Specialized Databases showing TM4SF1 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for TM4SF1 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for TM4SF1 Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property
for TM4SF1 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for TM4SF1 gene:
Search GeneIP for patents involving TM4SF1

GeneCards and IP:
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Products
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