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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SERINC3 Gene

protein-coding   GIFtS: 52
GCID: GC20M043124

serine incorporator 3

(Previous name: tumor differentially expressed 1 )
(Previous symbol: TDE1)
  Search for SERINC3
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SERINC3    

Aliases
for SERINC3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Serine Incorporator 31 2     TMS-11 2
TDE11 2 3 5     Tumor Differentially Expressed 11 2
DIFF331 2 3     Tumor Differentially Expressed Protein 12 3
AIGP11 2     Placental Transmembrane Protein (Mouse Testicular Tumor Differentially
Expressed)2
SBBI991 2     Transmembrane Protein SBBI992
TDE1 2     Tumour Differentially Expressed 12

External Ids:    HGNC: 116991   Entrez Gene: 109552   Ensembl: ENSG000001328247   OMIM: 6071655   UniProtKB: Q135303   

Export aliases for SERINC3 gene to outside databases

Previous GC identifers: GC20M042559 GC20M039866


Summaries
for SERINC3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: SERC3_HUMAN, Q13530
Function: May be involved in cellular transformation

Gene Wiki entry for SERINC3


Genomic Views
for SERINC3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SERINC3 gene promoter:
         Elk-1   LUN-1   LCR-F1   AREB6   MZF-1   E2F   E2F-1   Pax-4a   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SERINC3 promoter sequence
   Search SABiosciences Chromatin IP Primers for SERINC3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERINC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.12   Ensembl cytogenetic band:  20q13.12   HGNC cytogenetic band: 20q13.12

SERINC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERINC3 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M043124:  view genomic region     (about GC identifiers)

Start:
 43,124,862 bp from pter      End:
 43,150,750 bp from pter
Size:
 25,889 bases      Orientation:
 minus strand

Proteins
for SERINC3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SERC3_HUMAN, Q13530 (See protein sequence)
Recommended Name: Serine incorporator 3  
Size: 473 amino acids; 52580 Da
Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity)
Sequence caution: Sequence=AAB48858.1; Type=Frameshift; Positions=321, 393, 407, 459; Sequence=AAD34641.1;
Type=Frameshift; Positions=321, 393, 407, 459;
Secondary accessions: O43717 Q9BR33

Explore the universe of human proteins at neXtProt for SERINC3: NX_Q13530

Post-translational modifications:

  • N-glycosylated (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13530

    • SERINC3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_006802.1  NP_945179.1  

    ENSEMBL proteins: 
     ENSP00000414197   ENSP00000340243   ENSP00000255175   ENSP00000440966  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Purified Protein: SERINC3
    OriGene Protein Over-expression Lysate (see all 2): SERINC3
    OriGene Custom Protein Services for SERINC3 
    GenScript Custom Purified and Recombinant Proteins Services for SERINC3
    Novus Biologicals SERINC3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SERINC3

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0005886plasma membrane IEA--
    GO:0016021integral to membrane IEA--


    SERINC3 for ontologies           About GeneDecksing



    SERINC3 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of SERINC3
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    Search for Antibodies for SERINC3 at Abcam  
    Uscn Antibodies for SERINC3
    Search ThermoFisher Antibodies for SERINC3

    Assay Products for SERINC3: 
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    Uscn ELISAs and CLIAs for SERINC3

    Protein Domains /
    Families
    for SERINC3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SERINC3 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR005016 TMS_TDE

    Graphical View of Domain Structure for InterPro Entry Q13530

    ProtoNet protein and cluster: Q13530

    1 Blocks protein family: IPB005016 TMS membrane protein/tumour differentially expressed protein

    UniProtKB/Swiss-Prot: SERC3_HUMAN, Q13530
    Similarity: Belongs to the TDE1 family


    Function
    for SERINC3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SERC3_HUMAN, Q13530
    Function: May be involved in cellular transformation

    miRNA
    Products:            		miRTarBase miRNAs that target SERINC3:
    hsa-mir-204 (MIRT005842)

    OriGene 3'-UTR Clone (see all 2): SERINC3
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SERINC3
    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate SERINC3 (see all 20):
    hsa-miR-513a-5p hsa-miR-301a hsa-miR-340 hsa-miR-3133 hsa-miR-20b* hsa-miR-130b hsa-miR-412 hsa-miR-3671
    SwitchGear 3'UTR luciferase reporter plasmid: SERINC3 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SERINC3 (see all 7)
    OriGene shRNA RFP: SERINC3
    OriGene siRNA: SERINC3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERINC3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for SERINC3

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC3 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC3 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): SERINC3 (NM_006811)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERINC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERINC3 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for SERINC3
    Search LifeMap BioReagents cell lines for SERINC3

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERINC3

    Animal Models:
         1 MGI phenotypic allele for Serinc3 (no phenotypes)

    SERINC3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for SERINC3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SERINC3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/36 Interacting proteins for SERINC3 (Q135303 ENSP000002551754) via UniProtKB, MINT, STRING, and/or I2D (see all 36)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KDELR2P339473, ENSP000002587394I2D: score=2 STRING: ENSP00000258739
    SURF4O152603, ENSP000003610574I2D: score=2 STRING: ENSP00000361057
    VDAC2P458803, ENSP000003616864I2D: score=2 STRING: ENSP00000361686
    PTPLAD1Q9P0353, ENSP000002618754I2D: score=2 STRING: ENSP00000261875
    XPO5Q9HAV43, ENSP000002653514I2D: score=2 STRING: ENSP00000265351
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006917induction of apoptosis IEA--


    SERINC3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SERINC3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SERINC3
    Search CenterWatch for drugs/clinical trials and news about SERINC3 / SERC3 

    Transcripts
    for SERINC3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SERINC3 gene (2 alternative transcripts): 
    NM_006811.2  NM_198941.1  

    Unigene Cluster for SERINC3:

    Serine incorporator 3
    Hs.272168  [show with all ESTs]
    Unigene Representative Sequence: NM_006811
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000411544 ENST00000342374(uc002xmf.1 uc010ggs.1 uc010zwp.1)
    ENST00000468234 ENST00000255175(uc002xme.3) ENST00000541235

    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): SERINC3
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SERINC3
    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate SERINC3 (see all 20):
    hsa-miR-513a-5p hsa-miR-301a hsa-miR-340 hsa-miR-3133 hsa-miR-20b* hsa-miR-130b hsa-miR-412 hsa-miR-3671
    SwitchGear 3'UTR luciferase reporter plasmid: SERINC3 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SERINC3 (see all 7)
    OriGene shRNA RFP: SERINC3
    OriGene siRNA: SERINC3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERINC3
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC3 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC3 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): SERINC3 (NM_006811)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERINC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERINC3 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SERINC3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERINC3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERINC3

    Additional cDNA sequence: 

    AF112227.1 AF153979.1 AK222923.1 AK295120.1 AK300618.1 AK309993.1 BC006088.1 U49188.1 

    24/25 DOTS entries (see all 25):

    DT.454945  DT.95270601  DT.100702738  DT.100852073  DT.92325328  DT.100852076  DT.95270593  DT.95270578 
    DT.100829318  DT.100852071  DT.95270596  DT.100852078  DT.100852081  DT.120837493  DT.92448907  DT.40116277 
    DT.100044820  DT.120837413  DT.120837419  DT.120837505  DT.92058288  DT.92448911  DT.92428113  DT.95270572 

    24/706 AceView cDNA sequences (see all 706):

    AI962954 CB137183 BM671843 BI825213 CN485101 BU619212 CA424183 BF476018 
    W52041 AA975924 BQ128333 AI697551 CB993598 AW024289 AW338060 AA294859 
    BU690062 AI126446 BQ001450 CB123498 CB124727 BM453130 CB996545 BQ893173 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SERINC3 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12
    SP1:                    -     -     -           -                                                                           
    SP2:                    -     -     -           -                       -                                                   
    SP3:                    -                       -                                                                           
    SP4:                                                                                                              -         
    SP5:                    -     -     -                                                                                       


    ECgene alternative splicing isoforms for SERINC3

    Expression
    for SERINC3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SERINC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTTAATATAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SERINC3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LiverLiver LobuleLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)

    See SERINC3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SERINC3

    SOURCE GeneReport for Unigene cluster: Hs.272168

    UniProtKB/Swiss-Prot: SERC3_HUMAN, Q13530
    Tissue specificity: Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared
    with normal pulmonary tissues

        SABiosciences Expression via Pathway-Focused PCR Array including SERINC3: 
              Apoptosis 384HT in human mouse rat

    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERINC3
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERINC3

    Orthologs
    for SERINC3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SERINC3 gene from 8/26 species (see all 26)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SERINC31 serine incorporator 3 70.62(n)
    69.28(a)    		   419196  NM_001006291.1  NP_001006291.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SERINC36
    		 --
    		 72(a)
    		 1 ↔ 1
    		 4(144061454-144076294)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.12262 Transcribed sequence with weak similarity to protein more 73.64(n)    141991957 
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC1005356831 serine incorporator 3-like 62.33(n)
    58.42(a)    		   100535683  XM_003199409.1  XP_003199457.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta TMS16
    		 TMS1
    		 39(a)
    		 1 → many
    		 3L(16405822-16408486)
    worm
    (Caenorhabditis elegans)    		 Secernentea R11H6.26
    Y57E12AL.16
    		 Protein Y57E12AL.1, isoform a
    		 43(a)
    43(a)
    		 many ↔ many
    many ↔ many
    		 V(14597924-14600076)
    V(7060791-7062799)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G161801 serinc-domain containing protein 48.13(n)
    34.91(a)    		   838187  NM_001198079.1  NP_001185008.1 
    rice
    (Oryza sativa)    		 Liliopsida Os02g07929001 hypothetical protein 48.21(n)
    37.41(a)    		   4330983  NM_001054899.1  NP_001048364.1 


    ENSEMBL Gene Tree for SERINC3 (if available)
    TreeFam Gene Tree for SERINC3 (if available) 

    Paralogs
    for SERINC3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SERINC3 gene
    ENSG000002625602  SERINC42  SERINC12  SERINC52  SERINC22  
    4 SIMAP similar genes for SERINC3 using alignment to 5 protein entries:     SERC3_HUMAN (see all proteins):
    SERINC1    SERINC2    SERINC5    SERINC4

    SERINC3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SERINC3
    PGOHUM00000249396


    Genomic Variants
    for SERINC3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/479 NCBI SNPs in SERINC3 are shown (see all 479)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs61306261,2
    		C,H--43124478(+) CACTAG/TGGATA 1 -- ds50016Minor allele frequency- T:0.00NS EA NA 422
    rs1446499351,2
    		--43124558(+) TAGAGA/GAGCAA 1 -- ds50010--------
    rs1487106831,2
    		--43124594(+) AAACTA/TGGTTC 1 -- ds50010--------
    rs1902812441,2
    		--43124597(+) CTAGGC/TTCCCA 1 -- ds50010--------
    rs1828471191,2
    		--43124730(+) AGAACC/TCTTAA 1 -- ds50010--------
    rs1882063111,2
    		--43124856(+) CCTTAC/GAGGCA 1 -- ds50010--------
    rs130438331,2
    		C,H--43124910(+) TGTGGT/GTTCTA 1 -- ut314Minor allele frequency- G:0.00NS EA 416
    rs61037531,2
    		H--43124941(+) ACATAG/AGCATG 1 -- ut31 ese34Minor allele frequency- A:0.00NS EA 420
    rs1422900041,2
    		--43125070(+) CATAAA/GCCTAC 1 -- int10--------
    rs60939851,2
    		C,H--43125072(+) TAAGCC/TTACTA 1 -- int14Minor allele frequency- T:0.00NS EA 416

    HapMap Linkage Disequilibrium report for SERINC3 (43124862 - 43150750 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SERINC3: --

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    Disorders / Diseases
    for SERINC3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SERINC3 for disorders           About MalaCards

    SERINC3 for disorders           About GeneDecksing

    OMIM gene information: 607165    OMIM disorders: --


    Export disorders for SERINC3 gene to outside databases

    Publications
    for SERINC3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SERINC3 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with SERINC3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The human TDE gene homologue: localization to 20q13.1-13.3 and variable expression in human tumor cell lines and tissue. (PubMed id 10559794)1, 2, 3 Bossolasco M.... Mes-Masson A.-M. (1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    4. Meta-analysis identifies 29 additional ulcerative col itis risk loci, increasing the number of confirmed associations to 47. (PubMed id 21297633)1 Anderson C.A....Rioux J.D. (2011)
    5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    6. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
    7. Human TDE1, a TDE1/TMS family member, inhibits apoptosis in vitro and stimulates in vivo tumorigenesis. (PubMed id 16547497)1 Bossolasco M....Mes-Masson A.M. (2006)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
    10. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. (PubMed id 7566098)1 Adams M.D....White O. (1995)

    External Searches for SERINC3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    Genome Databases showing SERINC3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10955 HGNC: 11699 AceView: TDE1 Ensembl:ENSG00000132824 euGenes: HUgn10955
    ECgene: SERINC3 H-InvDB: SERINC3

    Other Databases showing SERINC3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SERINC3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SERINC3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SERINC3 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for SERINC3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SERINC3 gene:
    Search GeneIP for patents involving SERINC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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