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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SBF1 Gene

protein-coding   GIFtS: 57
GCID: GC22M050885

SET binding factor 1

 Explore 11 diseases affiliated with
SBF1 via our new
 Human Malady Compendium 
Biological research products
for SBF1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
SET Binding Factor 11 2     DENN/MADD Domain Containing 7A2
MTMR51 2 3 5     Myotubularin Related 52
DENND7A1 2     Myotubularin-Related Protein 52
SET-Binding Factor 12 3     Sbf13

External Ids:    HGNC: 105421   Entrez Gene: 63052   Ensembl: ENSG000001002417   OMIM: 6035605   UniProtKB: O952483   

Export aliases for SBF1 gene to outside databases

Previous GC identifers: GC22M047389 GC22M049017 GC22M049175 GC22M033773


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MTMR5_HUMAN, O95248
Function: Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically
inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe
protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in
fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating
RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound
form

Gene Wiki entry for SBF1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.1  NT_011526.7  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SBF1 gene promoter:
         ER-alpha   Egr-3   RelA   AP-2gamma   E4BP4   LCR-F1   C/EBPalpha   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SBF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SBF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.33   Ensembl cytogenetic band:  22q13.33   HGNC cytogenetic band: 22q13.33

SBF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SBF1 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M050885:  view genomic region     (about GC identifiers)

Start:
50,883,429 bp from pter      End:
50,913,464 bp from pter
Size:
30,036 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MTMR5_HUMAN, O95248 (See protein sequence)
Recommended Name: Myotubularin-related protein 5  
Size: 1867 amino acids; 208315 Da
Subunit: Interacts with the SET domain of MLL/HRX. Interacts with SUV39H1
Subcellular location: Nucleus
Sequence caution: Sequence=AAC39675.1; Type=Frameshift; Positions=1603, 1627, 1631, 1864;
Secondary accessions: A6PVG9 O60228 Q5JXD8 Q5PPM2 Q96GR9 Q9UGB8
Alternative splicing: 2 isoforms:  O95248-1   O95248-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SBF1: NX_O95248

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O95248

  • SBF1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002963.2  
    ENSEMBL proteins: 
     ENSP00000370196   ENSP00000252027   ENSP00000401538   ENSP00000375097  

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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SBF1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0016021integral to membrane TAS9736772


    SBF1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SBF1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SBF1 for domains           About GeneDecksing

    5/9 InterPro domains/families (see all 9):
     IPR022096 SBF2
     IPR005112 dDENN_dom
     IPR017906 Myotubularin_phosphatase_dom
     IPR010569 Myotub-related
     IPR001849 Pleckstrin_homology

    Graphical View of Domain Structure for InterPro Entry O95248

    ProtoNet protein and cluster: O95248

    1 Blocks protein family: IPB001849 Pleckstrin-like

    UniProtKB/Swiss-Prot: MTMR5_HUMAN, O95248
    Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily
    Similarity: Contains 1 dDENN domain
    Similarity: Contains 1 DENN domain
    Similarity: Contains 1 GRAM domain
    Similarity: Contains 1 myotubularin phosphatase domain
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 uDENN domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MTMR5_HUMAN, O95248
    Function: Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically
    inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe
    protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in
    fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating
    RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound
    form

         Genatlas biochemistry entry for SBF1:
    SET binding factor 1,expressed in skeletal muscle,heart,placenta,brain,liver and pancreas

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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005543phospholipid binding IEA--
    GO:0008138protein tyrosine/serine/threonine phosphatase activity TAS9736772
    GO:0016791phosphatase activity ----
    GO:0017112Rab guanyl-nucleotide exchange factor activity IDA--


    SBF1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SBF1:
     Increased apoptosis 

    Animal Models:
         Mouse knock-out Sbf1tm1Mlc for SBF1
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Sbf1):
     endocrine/exocrine gland  homeostasis/metabolism  mortality/aging  reproductive system 

    SBF1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SBF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/11 Interacting proteins for SBF1 (O952482, 3 ENSP000003750974) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDPK1O155302, 3MINT-8265599 I2D: score=2 
    TNFSF11O147882, 3, ENSP000002398494MINT-8274753 I2D: score=2 STRING: ENSP00000239849
    MTMR2Q136143, ENSP000003457524I2D: score=4 STRING: ENSP00000345752
    SIRT3Q9NTG73, ENSP000003721914I2D: score=2 STRING: ENSP00000372191
    SUV39H1O434633, ENSP000003658774I2D: score=2 STRING: ENSP00000365877
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006470protein dephosphorylation TAS9736772
    GO:0007283spermatogenesis IEA--


    SBF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SBF1
    Search CenterWatch for drugs/clinical trials and news about SBF1 / MTMR5 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SBF1 gene: 
    NM_002972.2  

    Unigene Cluster for SBF1:

    SET binding factor 1
    Hs.589924  [show with all ESTs]
    Unigene Representative Sequence: NM_002972
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000380817(uc003ble.3 uc011arx.2 uc003blh.3) ENST00000348911
    ENST00000418590 ENST00000470434 ENST00000473724 ENST00000476293 ENST00000477234
    ENST00000399627 ENST00000390679(uc003bli.2)

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    hsa-miR-302d hsa-miR-520e hsa-miR-3607-3p hsa-miR-429 hsa-miR-30d hsa-miR-372 hsa-miR-30a hsa-miR-637
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    Inhib. RNA
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    OriGene siRNA: SBF1
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    Additional cDNA sequence: 

    AB209682.1 AF072929.1 AK057985.1 BC009268.1 BC024101.1 BC040031.1 BC046169.2 BC056915.1 
    BC087612.1 BC111424.1 CR749672.1 U93181.1 

    24/28 DOTS entries (see all 28):

    DT.101985092  DT.101969523  DT.92003502  DT.100678079  DT.101985091  DT.317388  DT.100796866  DT.100887349 
    DT.91938406  DT.95218226  DT.100017313  DT.100761182  DT.100887348  DT.100668018  DT.91754729  DT.120634439 
    DT.120634469  DT.448541  DT.95249523  DT.99927098  DT.100887342  DT.120634512  DT.317390  DT.91746969 

    24/352 AceView cDNA sequences (see all 352):

    BQ066021 Z41182 CF138512 BE298418 CA868136 AA309922 BQ063357 AI333705 
    BX346444 BX367402 BX349809 AI934859 BI915606 AW293309 BQ436297 BI031319 
    BQ721484 CF135536 BI913615 AI304716 BX281388 AL120846 CA868377 BX281794 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SBF1 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^
    SP1:                                            -                                                                                                               
    SP2:                                                                                                                                                            
    SP3:                                            -                                                                                                               
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30a · 30b ^ 31a · 31b ^ 32a · 32b ^ 33a · 33b · 33c ^ 34 ^ 35a · 35b · 35c ^ 36a · 36b · 36c ^ 37 ^ 38 ^ 39 ^
    SP1:                                            -                       -                                                                                       
    SP2:                                      -     -                       -                                                                                       
    SP3:                                                                                                                                                            
    SP4:                                                                                                                          -     -                           
    SP5:                                                                    -                                   -                                                   

    ExUns: 40 ^ 41a · 41b
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for SBF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SBF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTACAGCCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SBF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SBF1

    SOURCE GeneReport for Unigene cluster: Hs.589924
        SABiosciences Custom PCR Arrays for SBF1
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SBF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SBF1 gene from 7/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves SBF11 SET binding factor 1 76.74(n)
    77.15(a)
      417071  XM_415358.3  XP_415358.3 
    lizard
    (Anolis carolinensis)
    Reptilia SBF16
    --
    77(a)
    1 ↔ 1
    GL343855.1(138442-160048)
    zebrafish
    (Danio rerio)
    Actinopterygii sbf11 SET binding factor 1 70.53(n)
    72.51(a)
      568277  NM_001045158.1  NP_001038623.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Sbf3 protein tyrosine/serine/threonine
    phosphatase
    38(a)   86F8   --
    worm
    (Caenorhabditis elegans)
    Secernentea H28G03.63   -- 26(a)   X(5270234-5278666)   --
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G045406
    MTM16
    Myotubularin-like phosphatases II-like protein
    17(a)
    16(a)
    many ↔ many
    many ↔ many
    5(1296442-1302444)
    3(3292899-3298522)
    rice
    (Oryza sativa)
    Liliopsida --
    inositol or phosphatidylinositol phosphatase/ phos...
    16(a)
    1 → many
    8(27856282-27865603)


    ENSEMBL Gene Tree for SBF1 (if available)
    TreeFam Gene Tree for SBF1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SBF1 gene
    MTMR42  MTMR72  MTMR122  MTMR22  MTMR102  MTM12  MTMR82  MTMR32  
    MTMR92  SBF22  MTMR62  MTMR112  MTMR12  
    4 SIMAP similar genes for SBF1 using alignment to 5 protein entries:     MTMR5_HUMAN (see all proteins):
    DKFZp761D0422    SBF2    DKFZp666I2310    DKFZp667L246

    SBF1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SBF1
    PGOHUM00000244600 PGOHUM00000249347


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/726 NCBI SNPs in SBF1 are shown (see all 726    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs356284741,2
    C--33790204(+) GGTAA-/GGGGGG 1 -- int12Minor allele frequency- G:0.00NA CSA 4
    rs1403561011,2
    C,--50882954(+) GAGCC-/GGGGTG
            
    GGGGT
    5 -- ut31 int10--------
    rs2016093911,2
    --50882966(+) GGGTG-/GGGGT 
            
    GGGGG
    5 -- int1 ut310--------
    rs340791141,2
    C,--50883048(+) TACAG-/TTTTTT 5 -- ut31 int11Minor allele frequency- T:0.00CSA 2
    rs10566761,2
    C,F,--50883058(+) TTTTTT/GTTGTT 5 -- ut31 int11Minor allele frequency- G:0.45MN 184
    rs666094651,2
    C,--50883058(-) AACAA-/CAAAAA 5 -- ut31 int11Minor allele frequency- C:0.00NA 2
    rs1379961971,2
    --50883091(+) AAGGAC/GCCAAG 5 -- int1 ut310--------
    rs1411187901,2
    --50883133(+) CAGGGA/CAGAGT 5 -- int1 ut310--------
    rs1917506481,2
    --50883154(+) GGTTGA/GAAAAA 5 -- int1 ut310--------
    rs1842069551,2
    --50883276(+) GCCTGA/GCAGGG 5 -- int1 ut310--------

    HapMap Linkage Disequilibrium report for SBF1 (50883429 - 50913464 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SBF1: --
    Human Gene Mutation Database (HGMD): SBF1

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SBF1 for disorders           About GeneDecksing

    OMIM gene information: 603560    OMIM disorders: --

    11 diseases for SBF1:    About MalaCards
    charcot-marie-tooth disease type 4    charcot-marie-tooth disease    charcot-marie-tooth disease type 4b2    early-onset glaucoma
    centronuclear myopathy    tooth disease    male infertility    myopathy
    glaucoma    infertility    azoospermia

    1 disease from the University of Copenhagen DISEASES database for SBF1:
    Centronuclear myopathy

    2 Novoseek disease relationships for SBF1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    centronuclear myopathy 90.4 1 9537414 (1)
    myopathy 47.9 1 9689104 (1)

    Human Genome Epidemiology (HuGE) Navigator: SBF1 (3 documents)

    Export disorders for SBF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SBF1 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with SBF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Association of SET domain and myotubularin-related proteins modulates growth control. (PubMed id 9537414)1, 2, 3, 9 Cui X.... Cleary M.L. (1998)
    2. Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human. (PubMed id 9736772)1, 2, 3 Laporte J....Mandel J.-L. (1998)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Set domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9. (PubMed id 10848615)1, 2 Firestein R.... Cleary M.L. (2000)
    5. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
    6. Pseudo-phosphatase Sbf1 contains an N-terminal GEF homology domain that modulates its growth regulatory properties. (PubMed id 11686296)1, 9 Firestein R. and Cleary M.L. (2001)
    7. Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase. (PubMed id 12668758)1, 9 Kim S.A....Dixon J.E. (2003)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6305 HGNC: 10542 AceView: SBF1 Ensembl:ENSG00000100241 euGenes: HUgn6305
    ECgene: SBF1 H-InvDB: SBF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SBF1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SBF1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SBF1 gene:
    Search GeneIP for patents involving SBF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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