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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RBM3 Gene

protein-coding GIFtS: 55
GCID: GC0XP048432

RNA binding motif (RNP1, RRM) protein 3

(Previous name: RNA binding motif protein 3 )

Explore 11 diseases affiliated with
RBM3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
RNA Binding Motif (RNP1, RRM) Protein 3¹ ²
IS1-RNPL¹ ²
RNPL² ³
RNA-Binding Motif Protein 3² ³
RNA Binding Motif Protein 3¹
Putative RNA-Binding Protein 3²

External Ids:	HGNC: 9900¹	Entrez Gene: 5935²	Ensembl: ENSG00000102317⁷	OMIM: 300027⁵	UniProtKB: P98179³

Export aliases for RBM3 gene to outside databases

Previous GC identifers: GC0XP047235 GC0XP046693 GC0XP047478 GC0XP048189 GC0XP048317 GC0XP046097

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RBM3:

This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition

motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on

chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have

been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. (provided by RefSeq,

Jul 2008)

UniProtKB/Swiss-Prot: RBM3_HUMAN, P98179

Function: Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild

hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of

translation initiation factors and active polysome formation (By similarity)

Gene Wiki entry for RBM3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000023.10 NC_018934.1 NT_079573.4

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RBM3 gene promoter:
E2F-4 E2F-3a E2F-5 AML1a E2F-2 E2F E2F-1 POU2F1 POU2F1a En-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RBM3 promoter sequence

Search SABiosciences Chromatin IP Primers for RBM3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBM3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.2 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.2

RBM3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBM3 gene location

GeneLoc information about chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XP048432: view genomic region (about GC identifiers)

Start:	48,432,836 bp from pter	End:	48,437,454 bp from pter
Size:	4,619 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RBM3_HUMAN, P98179 (See protein sequence)

Recommended Name: Putative RNA-binding protein 3

Size: 157 amino acids; 17170 Da

Subunit: Interacts with RPL4. Associates with the 60S ribosomal subunits in an RNA-independent manner. Associates with

ribosomes (By similarity)

Subcellular location: Nucleus (By similarity). Cytoplasm (By similarity). Cell projection, dendrite (By similarity).

Note=Localizes in mRNA granules in dentrites (By similarity)

Explore the universe of human proteins at neXtProt for RBM3: NX_P98179

Post-translational modifications:

Arg-105 is dimethylated, probably to asymmetric dimethylarginine¹

Phosphorylated (By similarity)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P98179

RBM3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_006734.1

ENSEMBL proteins:

ENSP00000365950 ENSP00000365946 ENSP00000346473 ENSP00000412764

Human Recombinant Protein Products:

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	Uscn Proteins for RBM3

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	ISS	--
GO:0005737	cytoplasm	ISS	--
GO:0015934	colocalizes with large ribosomal subunit	ISS	--
GO:0030425	dendrite	ISS	--

RBM3 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for RBM3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RBM3 for domains About GeneDecksing

2 InterPro domains/families:

IPR012677 Nucleotide-bd_a/b_plait

IPR000504 RRM_dom

Graphical View of Domain Structure for InterPro Entry P98179

ProtoNet protein and cluster: P98179

1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

UniProtKB/Swiss-Prot: RBM3_HUMAN, P98179

Similarity: Contains 1 RRM (RNA recognition motif) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RBM3_HUMAN, P98179

Function: Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild

hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of

translation initiation factors and active polysome formation (By similarity)

Induction: Up-regulated by hypoxia

Genatlas biochemistry entry for RBM3:

Y chromosome RNA recognition motif 3,ubiquitously expressed,with homology to RBM1,RBM2 (see symbols)

miRNA Products:		OriGene 3'-UTR Clone: RBM3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RBM3
		8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate RBM3 (see all 28):
		hsa-miR-194* hsa-miR-4254 hsa-miR-502-5p hsa-miR-16-1* hsa-miR-410 hsa-miR-340 hsa-miR-548a-3p hsa-miR-511

		SwitchGear 3'UTR luciferase reporter plasmid: RBM3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for RBM3

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		Search LifeMap BioReagents cell lines for RBM3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM3

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0003723	RNA binding	IEA	--
GO:0005515	protein binding	--	--
GO:0043023	ribosomal large subunit binding	IEA	--

RBM3 for ontologies About GeneDecksing

3 GenomeRNAi human phenotypes for RBM3:

Decreased influenza A/WSN/33 r

Increased homologous recombina

Synthetic lethal with c-Myc af

Animal Models:
Mouse knock-out Rbm3^tm1Ttg for RBM3
3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Rbm3):

cellular

embryogenesis

immune system

RBM3 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RBM3

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5/19 Interacting proteins for RBM3 (P98179^{2, 3} ENSP00000365946⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 19)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HNRNPA2B1	P22626²^,³, ENSP00000346694⁴	MINT-6629372 I2D: score=2 STRING: ENSP00000346694
CHAF1A	Q13111³, ENSP00000301280⁴	I2D: score=1 STRING: ENSP00000301280
MAP1LC3A	Q9H492³, ENSP00000363970⁴	I2D: score=1 STRING: ENSP00000363970
UBC	P0CG48³, ENSP00000344818⁴	I2D: score=1 STRING: ENSP00000344818
ABI1	Q8IZP0³	I2D: score=2

About this table

Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006396	RNA processing	TAS	8634703
GO:0006412	translation	IEA	--
GO:0006417	regulation of translation	ISS	--
GO:0009409	response to cold	IEA	--
GO:0035196	production of miRNAs involved in gene silencing by miRNA	IEA	--

RBM3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

RBM3 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RBM3
1 Novoseek chemical compound relationship for RBM3 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
h2o2	22.6	2	14649730 (1), 9245737 (1)

Search CenterWatch for drugs/clinical trials and news about RBM3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RBM3 gene (3 alternative transcripts):

NM_006743.4 NM_001017430.1 NM_001017431.1

Unigene Cluster for RBM3:

RNA binding motif (RNP1, RRM) protein 3

Hs.301404 [show with all ESTs]

Unigene Representative Sequence: NM_006743

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000472897 ENST00000488216 ENST00000466764 ENST00000490127 ENST00000491240

ENST00000489344 ENST00000376759(uc004dkf.2) ENST00000485213 ENST00000376755

ENST00000491236 ENST00000354480 ENST00000430348

miRNA Products:		OriGene 3'-UTR Clone: RBM3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RBM3
		8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate RBM3 (see all 28):
		hsa-miR-194* hsa-miR-4254 hsa-miR-502-5p hsa-miR-16-1* hsa-miR-410 hsa-miR-340 hsa-miR-548a-3p hsa-miR-511

		SwitchGear 3'UTR luciferase reporter plasmid: RBM3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RBM3 (see all 6) OriGene siRNA: RBM3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RBM3

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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBM3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBM3

Additional cDNA sequence:

AK000859.1 AK026664.1 AK129559.1 AK289614.1 AK309137.1 AY203954.1 BC006825.1

24/47 DOTS entries (see all 47):

DT.100892698 DT.449311 DT.100892690 DT.92389838 DT.100045139 DT.95275116 DT.100892696 DT.100892693

DT.100892700 DT.121286130 DT.101984235 DT.121286025 DT.205601 DT.100045141 DT.100650914 DT.95078581

DT.304491 DT.121286021 DT.99954613 DT.121286134 DT.92461094 DT.100892679 DT.92461076 DT.100892677

20 AceView cDNA sequences:

CR597294 CR626059 CR622284 CR589973 CR601924 CR621948 CR604888 CR602242

CR620824 CR615647 CR615516 CR591107 CR618991 CR615558 AK026664 BC006825

NM_006743 AY203954 AK000859 U28686

GeneLoc Exon Structure

5/15 Alternative Splicing Database (ASD) splice patterns (SP) for RBM3 (see all 15) About this scheme

ExUns:	1	^	2a	·	2b	·	2c	·	2d	·	2e	·	2f	^	3a	·	3b	·	3c	·	3d	^	4a	·	4b	^	5a	·	5b	·	5c	^	6a	·	6b	^	7a	·	7b	·	7c	^	8a	·	8b	·	8c	^	9	^	10a	·
SP1:															-		-		-		-										-		-		-		-		-		-
SP2:															-		-		-		-										-
SP3:															-		-		-		-						-		-		-
SP4:																															-		-		-		-		-		-
SP5:																															-

ExUns:	10b	^	11a	·	11b
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for RBM3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RBM3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTATCCAGG

About this image

RBM3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Renal Vesicle

Kidney

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RBM3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RBM3

SOURCE GeneReport for Unigene cluster: Hs.301404

SABiosciences Expression via Pathway-Focused PCR Array including RBM3:

Cardiotoxicity in human mouse rat

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBM3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for RBM3 gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	RBM3⁶ --	--	85(a) 76(a)	1 ↔ 1 possible ortholog	GL343252.1(30146-32365) GL343252.1(14484-20512)
zebrafish (Danio rerio)	Actinopterygii	zgc:112425⁶ cirbp⁶	cold inducible RNA binding protein	39(a) 33(a)	many ↔ many many ↔ many	2(59487737-59495440) 22(18766097-18770361)
worm (Caenorhabditis elegans)	Secernentea	R09B3.2⁶ R09B3.3⁶ (see all 4)	Protein R09B3.3 (see all 4)	45(a) 40(a) (see all 4)	possible ortholog possible ortholog (see all 4)	I(11909347-11910095) I(11910319-11911012)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT3G20930⁶ GR-RBP4⁶ (see all 21)	glycine-rich RNA-binding protein 4 (see all 21)	9(a) 35(a) (see all 21)	many ↔ many many ↔ many (see all 21)	3(7331721-7334029) 3(8606477-8608083)
rice (Oryza sativa)	Liliopsida	Os07g0602600¹	hypothetical protein	53.38(n) 52.9(a)		4343831 NM_001066741.1 NP_001060206.1

ENSEMBL Gene Tree for RBM3 (if available)
TreeFam Gene Tree for RBM3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RBM3 gene

RBMY1E² RBMY1J² RBMY1F² RBMXL2² RBMXL3² TRA2B² RBMY1B² RBMXL1²

RBMY1A1² CIRBP² TRA2A² RBMX² RBMY1D²

18/35 SIMAP similar genes for RBM3 using alignment to 4 protein entries: RBM3_HUMAN (see all proteins) (see all similar genes):

CIRBP DAZAP1/MEF2D fusion RBMX RBM23 RBMXL3 RNPC4

RBMY1A1 DKFZp686A11192 DKFZp686C17209 DKFZp781C0423 RBM39 DAZAP1

CSTF2 HNRNPA2B1 RBM38 NCL RBMXL2 SRSF2

RBM3 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for RBM3
PGOHUM00000259596

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr X pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs2864303^1,2	A	--	46117373(+)	`CATGTC/TTTaaa`	2	--	us2k¹		0	--	--	--	--
rs189603821^1,2		--	48431016(+)	`GGGGGA/GAAAAT`	1	--	us2k¹		0	--	--	--	--
rs191345548^1,2		--	48431113(+)	`TTCCAA/GCACCT`	1	--	us2k¹		0	--	--	--	--
rs11798919^1,2	H	--	48431201(+)	`ATATGC/GATGTA`	1	--	us2k¹		0	--	--	--	--
rs144627083^1,2		--	48431243(+)	`TGTTGC/GGCAAA`	1	--	us2k¹		0	--	--	--	--
rs184407770^1,2		--	48431303(+)	`CTTCGC/TTGATG`	1	--	us2k¹		0	--	--	--	--
rs77558959^1,2	C	--	48431851(+)	`TCCTCC/TTTTGT`	1	--	us2k¹		0	--	--	--	--
rs7472809^1,2	A	--	48432009(+)	`tttttC/Tttttt`	1	--	us2k¹ trp³		0	--	--	--	--
rs9724236^1,2	C	--	48432019(+)	`TTTTTC/TTTTTT`	1	--	us2k¹ trp³		0	--	--	--	--
rs5906679^1,2	C	--	48432036(+)	`ttttgG/Tatttt`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for RBM3 (48432836 - 48437454 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RBM3
1 CNV: 7789
1 Indel: 73969

SABiosciences Cancer Mutation PCR Assays

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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RBM3 for disorders           About GeneDecksing

OMIM gene information: 300027    OMIM disorders: --

11 diseases for RBM3:    About MalaCards

amyotrophic lateral sclerosis lateral sclerosis epithelial ovarian cancer cryptorchidism

ovarian cancer vaccinia prostate cancer breast cancer

hypoxia prostatitis melanoma

Export disorders for RBM3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for RBM3 gene, integrated from 9 sources (see all 36):
(articles sorted by number of sources associating them with RBM3)

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RBM3, a novel human gene in Xp11.23 with a putative RNA-binding domain. (PubMed id 8634703)^{1, 2, 3} Derry J.M.... Francke U. (1995)
Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism. (PubMed id 15075239)^{1, 2, 9} Wellmann S.... Seeger K. (2004)
The DNA sequence of the human X chromosome. (PubMed id 15772651)^{1, 2} Ross M.T.... Bentley D.R. (2005)
Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)^{1, 2} Brill L.M....Peters E.C. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Increased transcript level of RBM3, a member of the glycine-rich RNA-binding protein family, in human cells in response to cold stress. (PubMed id 9245737)^{1, 9} Danno S....Fujita J. (1997)
The internal ribosome entry site (IRES) contained within the RNA-binding motif protein 3 (Rbm3) mRNA is composed of functionally distinct elements. (PubMed id 12824175)^{1, 9} Chappell S.A. and Mauro V.P. (2003)
The RNA-binding protein RBM3 is required for cell pro liferation and protects against serum deprivation-induced cell death. (PubMed id 19770690)^{1, 9} Wellmann S....BA1hrer C. (2010)
Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity. (PubMed id 19277990)^{1, 9} Zeng Y....Getzenberg R.H. (2009)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 5935	HGNC: 9900	AceView: RBM3	Ensembl:ENSG00000102317	euGenes: HUgn5935
ECgene: RBM3	H-InvDB: RBM3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for RBM3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RBM3 gene
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Patent Information for RBM3 gene:
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RNA binding motif (RNP1, RRM) protein 3

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