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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PLEKHG2 Gene

protein-coding   GIFtS: 52
GCID: GC19P039903

pleckstrin homology domain containing, family G (with RhoGef...

 Explore 3 diseases affiliated with
PLEKHG2 via our new
 Human Malady Compendium 
Biological research products
for PLEKHG2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member
21 2
     FLJ000181
CLG1 2 5     Common-Site Lymphoma/Leukemia Guanine Nucleotide Exchange Factor2
ARHGEF421 2     Pleckstrin Homology Domain-Containing Family G Member 22
PH Domain-Containing Family G Member 22 3     

External Ids:    HGNC: 295151   Entrez Gene: 648572   Ensembl: ENSG000000909247   OMIM: 6118935   UniProtKB: Q9H7P93   

Export aliases for PLEKHG2 gene to outside databases

Previous GC identifers: GC19P044596 GC19P036350


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PKHG2_HUMAN, Q9H7P9
Function: May be a transforming oncogene with exchange activity for CDC42 (By similarity). May be a guanine-nucleotide
exchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits beta and gamma of the heterotrimeric
guanine nucleotide-binding protein (G protein)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PLEKHG2 gene promoter:
         c-Fos   Sox5   AP-1   p300   c-Ets-1   HEN1   c-Jun   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPLEKHG2 promoter sequence
   Search SABiosciences Chromatin IP Primers for PLEKHG2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PLEKHG2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.2

PLEKHG2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PLEKHG2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P039903:  view genomic region     (about GC identifiers)

Start:
39,903,225 bp from pter      End:
39,919,055 bp from pter
Size:
15,831 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PKHG2_HUMAN, Q9H7P9 (See protein sequence)
Recommended Name: Pleckstrin homology domain-containing family G member 2  
Size: 1386 amino acids; 147969 Da
Sequence caution: Sequence=BAB15364.1; Type=Frameshift; Positions=84; Sequence=BAB15719.1; Type=Erroneous initiation;
Note=Translation N-terminally shortened;
Secondary accessions: B8ZZK6 C9J0Y4 Q6DHV6 Q96BU2 Q96D18 Q9H699
Alternative splicing: 3 isoforms:  Q9H7P9-1   Q9H7P9-2   Q9H7P9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PLEKHG2: NX_Q9H7P9

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H7P9

  • PLEKHG2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_073746.2  
    ENSEMBL proteins: 
     ENSP00000386733   ENSP00000397615   ENSP00000386492   ENSP00000412818   ENSP00000205135  
     ENSP00000408857   ENSP00000392906   ENSP00000367812  
    Reactome Protein details: Q9H7P9
    Human Recombinant Protein Products: 
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    Uscn Proteins for PLEKHG2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--


    PLEKHG2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PLEKHG2 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR000219 DH-domain
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q9H7P9

    ProtoNet protein and cluster: Q9H7P9

    2 Blocks protein families:
    IPB000219 DH domain
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: PKHG2_HUMAN, Q9H7P9
    Similarity: Contains 1 DH (DBL-homology) domain
    Similarity: Contains 1 PH domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: PKHG2_HUMAN, Q9H7P9
    Function: May be a transforming oncogene with exchange activity for CDC42 (By similarity). May be a guanine-nucleotide
    exchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits beta and gamma of the heterotrimeric
    guanine nucleotide-binding protein (G protein)

    miRNA
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    hsa-miR-495 hsa-miR-7-2* hsa-miR-378b hsa-miR-146a* hsa-miR-422a hsa-miR-10b* hsa-miR-2355-5p hsa-miR-7-1*
    SwitchGear 3'UTR luciferase reporter plasmidPLEKHG2 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005089Rho guanyl-nucleotide exchange factor activity IEA--
    GO:0005543phospholipid binding IEA--


    PLEKHG2 for ontologies           About GeneDecksing


    4 GenomeRNAi human phenotypes for PLEKHG2:
     G0/1 arrest  Increased G1 DNA content  Synthetic lethal with Ras  Upregulation of NF-kappaB path 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell death signalling via NRAGE, NRIF and NADE
    Cell death signalling via NRAGE, NRIF and NADE1.00
    G alpha (12/13) signalling events0.39
    NRAGE signals death through JNK0.74
    Rho GTPase cycle0.25
    p75 NTR receptor-mediated signalling0.73
    Signaling by Rho GTPases0.25
    2Signaling by GPCR
    Signaling by GPCR1.00
    Signal Transduction0.56
    GPCR downstream signaling0.89
    3Signaling by FGFR
    Signalling by NGF0.52

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/10        Reactome Pathways for PLEKHG2 (see all 10)
        GPCR downstream signaling
    Signaling by Rho GTPases
    G alpha (12/13) signalling events
    Cell death signalling via NRAGE, NRIF and NADE
    Signaling by GPCR



    PLEKHG2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PLEKHG2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/51 Interacting proteins for PLEKHG2 (Q9H7P93 ENSP000003867334) via UniProtKB, MINT, STRING, and/or I2D (see all 51)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RHOAP615863, ENSP000004001754I2D: score=2 STRING: ENSP00000400175
    CDC42P609533, ENSP000003144584I2D: score=2 STRING: ENSP00000314458
    RAC1P630003, ENSP000003484614I2D: score=2 STRING: ENSP00000348461
    ARHGAP18ENSP000002751894STRING: ENSP00000275189
    ARHGEF1ENSP000003372614STRING: ENSP00000337261
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process TAS--
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0035023regulation of Rho protein signal transduction IEA--
    GO:0048011nerve growth factor receptor signaling pathway TAS--
    GO:0051056regulation of small GTPase mediated signal transduction TAS--


    PLEKHG2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PLEKHG2 gene: 
    NM_022835.2  

    Unigene Cluster for PLEKHG2:

    Pleckstrin homology domain containing, family G (with RhoGef domain) member 2
    Hs.631574  [show with all ESTs]
    Unigene Representative Sequence: NM_022835
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409794(uc010xuy.2) ENST00000438123 ENST00000409797(uc002olj.3)
    ENST00000451354 ENST00000205135 ENST00000478523 ENST00000474449 ENST00000458508
    ENST00000425673(uc010xuz.2 uc010xva.2) ENST00000378550

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    hsa-miR-495 hsa-miR-7-2* hsa-miR-378b hsa-miR-146a* hsa-miR-422a hsa-miR-10b* hsa-miR-2355-5p hsa-miR-7-1*
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    Additional cDNA sequence: 

    AK024429.1 AK026111.1 AK095957.1 AK302476.1 AL832850.1 BC013426.1 BC015174.1 BC075858.1 

    9 DOTS entries:

    DT.75102878  DT.92015630  DT.100812222  DT.100812221  DT.100036087  DT.100036088  DT.121445411  DT.97815546 
    DT.95331991 

    24/172 AceView cDNA sequences (see all 172):

    BM917933 BU634129 BQ642467 AW968326 CA422169 BQ894005 BQ687283 AA806884 
    BQ006024 BG830165 BM473901 BQ890594 AA257988 BQ689255 BX646380 BM701791 
    CA308778 AI827787 BC075858 AA767907 BF854541 AA932213 AW025764 BF445414 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for PLEKHG2 (see all 12)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^
    SP1:                                                                                                                                                            
    SP2:                                                                                            -                                                               
    SP3:                                                                                                                                                            
    SP4:              -     -     -     -                                                                                                                           
    SP5:              -     -     -     -                                                                                                                           

    ExUns: 20 ^ 21 ^ 22
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for PLEKHG2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PLEKHG2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAATGATGTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See PLEKHG2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PLEKHG2

    SOURCE GeneReport for Unigene cluster: Hs.631574
        SABiosciences Custom PCR Arrays for PLEKHG2
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PLEKHG2 gene from 5/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Plekhg21 , 5 pleckstrin homology domain containing, family G (with more1, 5 77.41(n)1
    74.36(a)1
      7 (16.71 cM)5
    1014971  NM_138752.21  NP_620091.21 
     283596045 
    lizard
    (Anolis carolinensis)
    Reptilia PLEKHG26
    --
    63(a)
    1 ↔ 1
    GL344052.1(18511-42005)
    zebrafish
    (Danio rerio)
    Actinopterygii plekhg26
    CABZ01086294.16
    --
    63(a)
    11(a)
    1 ↔ 1
    possible ortholog
    15(19268099-19303138)
    17(1292918-1317812)
    fruit fly
    (Drosophila melanogaster)
    Insecta GEFmeso6
    Guanine nucleotide exchange factor in mesoderm
    12(a)
    possible ortholog
    2R(14441624-14499260)
    worm
    (Caenorhabditis elegans)
    Secernentea uig-16
    UNC-112-Interacting Guanine nucleotide exchange fa...
    16(a)
    possible ortholog
    V(13273553-13295900)


    ENSEMBL Gene Tree for PLEKHG2 (if available)
    TreeFam Gene Tree for PLEKHG2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PLEKHG2 gene
    ARHGEF62  VAV12  PLEKHG32  PREX22  ARHGEF72  TIAM12  SPATA132  TIAM22  
    ARHGEF92  VAV32  VAV22  ARHGEF42  PLEKHG12  PREX12  
    2 SIMAP similar genes for PLEKHG2 using alignment to 12 protein entries:     PKHG2_HUMAN (see all proteins):
    PLEKHG3    PLEKHG1

    PLEKHG2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/406 NCBI SNPs in PLEKHG2 are shown (see all 406    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1449019371,2
    --39901800(+) TTCATA/GGCAGC 2 -- us2k10--------
    rs1181696871,2
    F,--39902042(+) TCATCC/TATAGG 2 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1406968151,2
    --39902169(+) CTGCTC/GTTGCA 2 -- us2k10--------
    rs41001781,2
    --39902180(-) ggggtC/Gtggat 2 -- us2k1 tfbs30--------
    rs356868581,2
    C,F,H,--39902339(+) TGTTCA/GCTGCT 1 -- us2k120Minor allele frequency- G:0.39NS EA NA CSA WA 2344
    rs1846958191,2
    --39902468(+) TAGCTA/GTGTTC 1 -- us2k10--------
    rs1164315311,2
    --39902522(+) GCAGAG/CTCATA 1 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1385034531,2
    --39902609(+) AGAGAC/TGATAC 1 -- us2k10--------
    rs1429475621,2
    --39902700(+) TCTTTC/TGAGCC 1 -- us2k10--------
    rs1433605271,2
    --39902721(+) AAAGAC/TAGAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PLEKHG2 (39903225 - 39919055 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PLEKHG2: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PLEKHG2 for disorders           About GeneDecksing

    OMIM gene information: 611893    OMIM disorders: --

    3 diseases for PLEKHG2:    About MalaCards
    leukemia    myeloid leukemia    spasticity

    Human Genome Epidemiology (HuGE) Navigator: PLEKHG2 (1 document)

    Export disorders for PLEKHG2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PLEKHG2 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with PLEKHG2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42. (PubMed id 18045877)1, 2, 3 Ueda H.... Asano T. (2008)
    2. Activation of clg, a novel dbl family guanine nucleotide exchange factor gene, by proviral insertion at evi24, a common integration site in B cell and myeloid leukemias. (PubMed id 11839748)1, 3, 9 Himmel K.L....Largaespada D.A. (2002)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    5. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    6. Mutation of ARHGAP9 in patients with coronary spastic angina. (PubMed id 19911011)1 Takefuji M....Kaibuchi K. (2010)
    7. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
    10. Ten years on: mediation of cell death by the common n eurotrophin receptor p75(NTR). (PubMed id 12787561)1 Rabizadeh S. and Bredesen D.E. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64857 HGNC: 29515 AceView: CLG Ensembl:ENSG00000090924 euGenes: HUgn64857
    ECgene: PLEKHG2 H-InvDB: PLEKHG2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PLEKHG2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for PLEKHG2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PLEKHG2 gene:
    Search GeneIP for patents involving PLEKHG2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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