PIP4K2B Gene
protein-coding GIFtS: 57
GCID: GC17M036921
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|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta(Previous names: phosphatidylinositol-4-phosphate 5-kinase, type II, beta...)
(Previous symbol: PIP5K2B)
| |
Aliases
for PIP4K2B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, Beta1 2 | | PI(5)P 4-Kinase Type II Beta2 3 | | PIP5K2B1 2 3 | | EC 2.7.1.1493 8 | | PIP5KIIB1 2 | | 1-Phosphatidylinositol-4-Phosphate Kinase2 | | PIP5KIIbeta1 2 | | 1-Phosphatidylinositol-5-Phosphate 4-Kinase 2-Beta2 | | Phosphatidylinositol-4-Phosphate 5-Kinase, Type II, Beta1 2 | | PI5P4KB2 | | Diphosphoinositide Kinase 2-Beta2 3 | | PTDINS(4)P-5-Kinase1 | | Phosphatidylinositol 5-Phosphate 4-Kinase Type II Beta2 3 | | Phosphatidylinositol 5-Phosphate 4-Kinase Type-2 Beta2 | | PtdIns(5)P-4-Kinase Isoform 2-Beta2 3 | | Phosphatidylinositol-5-Phosphate 4-Kinase Type-2 Beta2 | | 1-Phosphatidylinositol 5-Phosphate 4-Kinase 2-Beta2 3 | | EC 2.7.18 | | PIP4KII-Beta1 | | |
Export aliases for PIP4K2B gene to outside databasesPrevious GC identifers: GC17M034175 GC17M032718 |
Summaries
for PIP4K2B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PIP4K2B:
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourthhydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of thephosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to otherkinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNFreceptor. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: PI42B_HUMAN, P78356Function: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate
Gene Wiki entry for PIP4K2B
|
Genomic Views
for PIP4K2B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PIP4K2B gene promoter:
Pax-5 AML1a CUTL1 Nkx2-5 NF-E2 p45 Egr-4 CP2 NF-E2 Zic3
Other transcription factors
Search SABiosciences Chromatin IP Primers for PIP4K2B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PIP4K2B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q12 Ensembl cytogenetic band: 17q12 HGNC cytogenetic band: 17q21.2PIP4K2B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M036921: view genomic region
(about GC identifiers)
Start:
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36,921,942 bp from pter |
End:
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36,956,379 bp from pter |
Size:
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34,438 bases |
Orientation:
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minus strand |
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Proteins
for PIP4K2B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PI42B_HUMAN, P78356 (See
protein sequence)Recommended Name: Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Size: 416 amino acids; 47378 Da
Subunit: Homodimer. Binds TNFRSF1A. Interacts with PIP4K2A. Interaction with PIP4K2A suppresses ubiquitination by theSPOP/ CUL3 complex
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Cell membrane;Peripheral membrane protein (By similarity). Nucleus. Cytoplasm. Note=Associated with the plasma membrane and theendoplasmic reticulum (By similarity)
1 PDB 3D structure from  and Proteopedia  for PIP4K2B:1BO1 (3D)
Secondary accessions: Q5U0E8 Q8TBP2Alternative splicing: 2 isoforms: P78356-1 P78356-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for PIP4K2B: NX_P78356
Post-translational modifications:
Ubiquitinated by the SPOP/CUL3 complex. Ubiquitination is stimulated by PtdIns5P levels1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P78356
4/17 DME Specific Peptides for PIP4K2B (P78356) (see all 17)
PIP4K2B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003550.1
ENSEMBL proteins: ENSP00000269554 ENSP00000463831 Reactome Protein details: P78356
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
PIP4K2B for ontologies About GeneDecksing
PIP4K2B Antibody Products:
Assay Products for PIP4K2B: |
Protein
Domains /
Families
for PIP4K2B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PIP4K2B for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P78356ProtoNet protein and cluster: P78356 1 Blocks protein family: IPB002498 Phosphatidylinositol-4-phosphate 5-kinase
UniProtKB/Swiss-Prot: PI42B_HUMAN, P78356Similarity: Contains 1 PIPK domain |
Function
for PIP4K2B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PI42B_HUMAN, P78356Function: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphateCatalytic activity: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol4,5-bisphosphateBiophysicochemical properties: Kinetic parameters: KM=30 uM for phosphatidylinositol-5- phosphate; Vmax=0.2 pmol/min/ugenzyme;Enzyme Numbers (IUBMB): EC 2.7.1.1491 2 EC 2.7.12
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PIP4K2B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PIP4K2B (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PIP4K2B (NM_003559) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PIP4K2B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PIP4K2B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIP4K2B |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
PIP4K2B for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for PIP4K2B:
Animal Models:
6 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Pip4k2b):
PIP4K2B for phenotypes About GeneDecksing
|
Pathways & Interactions
for PIP4K2B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Inositol phosphate metabolism | | | 2 | PI Metabolism | | | 3 | Metabolism | | | 4 | Regulation of Actin Cytoskeleton | | | 5 | Ca, cAMP and Lipid Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for PIP4K2B
5  BioSystems Pathways for PIP4K2B
5 
Reactome Pathways for PIP4K2B
3 
Kegg Pathways (Kegg details for PIP4K2B):
PIP4K2B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PIP4K2B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/51 Interacting proteins for PIP4K2B (P783562, 3 ENSP000002695544) via UniProtKB, MINT, STRING, and/or I2D (see all 51)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006644 | phospholipid metabolic process |
TAS | -- | | GO:0006661 | phosphatidylinositol biosynthetic process |
TAS | -- | | GO:0007166 | cell surface receptor signaling pathway |
TAS | 9038203 | | GO:0044281 | small molecule metabolic process |
TAS | -- | | GO:0046488 | phosphatidylinositol metabolic process |
-- | -- |
PIP4K2B for ontologies About GeneDecksing
|
Drugs & Compounds
for PIP4K2B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PIP4K2B
3 HMDB Compounds for PIP4K2B About this table
Search CenterWatch for drugs/clinical trials and news about PIP4K2B / PI42B
|
Transcripts
for PIP4K2B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PIP4K2B gene (2 alternative transcripts): NM_003559.4 NM_138687.1 Unigene Cluster for PIP4K2B: Phosphatidylinositol-5-phosphate 4-kinase, type II, beta Hs.743962 [show with all ESTs]Unigene Representative Sequence: NM_0035594 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000269554(uc002hqs.3 uc021twj.1) ENST00000583278 ENST00000311500
ENST00000581097
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PIP4K2B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PIP4K2B (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PIP4K2B (NM_003559) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PIP4K2B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PIP4K2B |
Additional cDNA sequence: AK307169.1 BC027459.1 BC073896.1 BC094858.1 BT019614.1 U85245.1 13 DOTS entries: DT.92439356 DT.95235928 DT.92439370 DT.92439371 DT.97860523 DT.95274610 DT.219375 DT.120892109 DT.95076456 DT.95222711 DT.97860525 DT.120892117 DT.95303157 24/426 AceView cDNA sequences (see all 426): BE938197 BM770861 Z42408 BE797286 BM142393 BQ029882 BM727194 CR624711 BM770797 BF941636 BM560612 BM771362 T17324 AU280563 BI493812 Z38581 AA112176 AA300326 NM_003559 AA084038 BM757017 BM771444 AA600246 AI033165
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for PIP4K2B About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PIP4K2B
|
Expression
for PIP4K2B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PIP4K2B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTACGATGAA
About this image
See PIP4K2B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PIP4K2B
SOURCE GeneReport for Unigene cluster: Hs.743962
UniProtKB/Swiss-Prot: PI42B_HUMAN, P78356Tissue specificity: Highly expressed in brain, heart, pancreas, skeletal muscle and kidney. Detected at lower levels inplacenta, lung and liver
SABiosciences Custom PCR Arrays for PIP4K2B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PIP4K2B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PIP4K2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PIP4K2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PIP4K2B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIP4K2B |
Orthologs
for PIP4K2B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for PIP4K2B gene from 6/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
PIP4K2B1 |
phosphatidylinositol-5-phosphate 4-kinase, type II, more |
85.4(n)
95.87(a) |
|
419999 XM_418120.2 XP_418120.2 |
lizard
(Anolis carolinensis) |
Reptilia |
PIP4K2B6 |
-- |
93(a) |
1 ↔ 1 |
6(63106838-63142079) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.18242 |
Xenopus laevis phosphatidylinositol-4-phosphate 5-kinase more |
81.38(n) |
|
AF495661.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC5559201 |
novel protein similar to vertebrate phosphatidylinositol-4-phosphate more |
73.45(n)
74.26(a) |
|
555920 XM_678580.4 XP_683672.2 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG174711 |
CG17471 |
58.99(n)
61.38(a) |
|
3885565 NM_001038716.1 NP_001033805.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
ppk-21 |
Protein PPK-2 |
56.25(n)
55.73(a) |
|
175344 NM_065099.3 NP_497500.1 |
ENSEMBL Gene Tree for PIP4K2B (if available)
TreeFam Gene Tree for PIP4K2B (if available) |
Paralogs
for PIP4K2B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PIP4K2B gene
- PIP4K2A2 PIP5K1B2 PIP4K2C2 PIP5K1C2 PIP5KL12 PIP5K1A2
6 SIMAP similar genes for PIP4K2B using alignment to 2 protein entries: PI42B_HUMAN (see all proteins):PIP4K2A PIP4K2C PIP5K1A PIP5K1C PIPSL PIP5K1B
PIP4K2B for paralogs About GeneDecksing
|
Genomic Variants
for PIP4K2B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PIP4K2B (36921942 - 36956379 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PIP4K2B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PIP4K2B |
|
Disorders
/ Diseases
for PIP4K2B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PIP4K2B for disorders About GeneDecksing
OMIM gene information: 603261
OMIM disorders: --
2  diseases for PIP4K2B: About MalaCardsbreast cancer ataxia
Human Genome Epidemiology (HuGE) Navigator: PIP4K2B (1 document)
Export disorders for PIP4K2B gene to outside databases
|
Publications
for PIP4K2B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PIP4K2B gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with PIP4K2B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5- kinase. (PubMed id 9038203)1, 2, 3, 9 Castellino A.M....Chao M.V. (1997)
- Overexpression of the amplified Pip4k2beta gene from 17q11-12 in breast cancer cells confers proliferation advantage. (PubMed id 14691457)1, 3 Luoh S.W....Tripathi R. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation. (PubMed id 9753329)1, 2 Rao V.D.... Hurley J.H. (1998)
- A new pathway for synthesis of phosphatidylinositol-4,5- bisphosphate. (PubMed id 9367159)1, 3 Rameh L.E.... Cantley L.C. (1997)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Phosphatidylinositol 5-phosphate 4-kinase type II bet a is required for vitamin D receptor-dependent E-cadherin expression in SW480 c ells. (PubMed id 21514270)1 Kouchi Z....Fukami K. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for PIP4K2B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PIP4K2B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PIP4K2B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PIP4K2B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PIP4K2B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PIP4K2B gene:
Search GeneIP for patents involving PIP4K2B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PIP4K2B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for PIP4K2B | | OriGene shRNA RFP for PIP4K2B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PIP4K2B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PIP4K2B | | | OriGene Protein Over-expression Lysate for PIP4K2B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PIP4K2B | | OriGene 3'-UTR Clone for PIP4K2B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PIP4K2B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PIP4K2B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PIP4K2B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PIP4K2B | | OriGene Custom Protein Services for PIP4K2B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PIP4K2B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PIP4K2B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PIP4K2B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PIP4K2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PIP4K2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PIP4K2B |
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| | | | Search Tocris compounds for PIP4K2B |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIP4K2B |
|  |  |  | | | | ThermoFisher Antibodies for PIP4K2B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PIP4K2B |
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