NUMBL Gene
protein-coding GIFtS: 61
GCID: GC19M041171
|
|
numb homolog (Drosophila)-like(Previous name: numb (Drosophila) homolog-like )
| |
Aliases
for NUMBL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Numb Homolog (Drosophila)-Like1 2 | | Numb-Related Protein2 3 | | NUMBR1 2 5 | | NBL2 5 | | CAG3A1 2 | | Numb (Drosophila) Homolog-Like1 | | CTG3a1 2 | | Numb Homolog-Like2 | | NUMB-R1 2 | | Numb-Like Protein2 | | NUMBLIKE1 2 | | Numb-R3 | | TNRC231 2 | | |
Export aliases for NUMBL gene to outside databasesPrevious GC identifers: GC19M041812 GC19M041564 GC19M045848 GC19M045864 GC19M045859 GC19M037605 |
Summaries
for NUMBL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: NUMBL_HUMAN, Q9Y6R0Function: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neuralprogenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor overneuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonicneurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblastssurvival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition ofNF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains ofTRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons
Gene Wiki entry for NUMBL
|
Genomic Views
for NUMBL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NUMBL gene promoter:
COUP-TF1 Sp1 p53 Lmo2 COUP HNF-4alpha2 GATA-2 HNF-4alpha1 COUP-TF
Other transcription factors
Search SABiosciences Chromatin IP Primers for NUMBL
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUMBL |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.13-q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.13-q13.2NUMBL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M041171: view genomic region
(about GC identifiers)
Start:
|
41,171,810 bp from pter |
End:
|
41,196,556 bp from pter |
Size:
|
24,747 bases |
Orientation:
|
minus strand |
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Proteins
for NUMBL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NUMBL_HUMAN, Q9Y6R0 (See
protein sequence)Recommended Name: Numb-like protein Size: 609 amino acids; 64891 Da
Subunit: Interacts (via PTB domain) with MAP3K7IP2 (via C-terminal). Interacts (via C-terminal) with TRAF6 (via TRAFdomains). Associates with EPS15 and NOTCH1
Subcellular location: Cytoplasm (By similarity). Note=Symmetrically distributed throughout the cytoplasm in nondividing neuroblasts of the CNS (By similarity)
1 PDB 3D structure from  and Proteopedia  for NUMBL:3F0W (3D)
Secondary accessions: Q7Z4J9Explore the universe of human proteins at neXtProt for NUMBL: NX_Q9Y6R0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y6R0
NUMBL Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004747.1
ENSEMBL proteins: ENSP00000252891 ENSP00000442759
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
NUMBL for ontologies About GeneDecksing
NUMBL Antibody Products:
Assay Products for NUMBL: |
Protein
Domains /
Families
for NUMBL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NUMBL for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y6R0ProtoNet protein and cluster: Q9Y6R0 2 Blocks protein families: IPB006020 Phosphotyrosine interaction domain IPB010449 NUMB phenylalanine-rich
UniProtKB/Swiss-Prot: NUMBL_HUMAN, Q9Y6R0Domain: The PTB domain is necessary for the inhibition of MAP3K7IP2-mediated activation of NF-kappa-BSimilarity: Contains 1 PID domain |
Function
for NUMBL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NUMBL_HUMAN, Q9Y6R0Function: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neuralprogenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor overneuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonicneurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblastssurvival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition ofNF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains ofTRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons Genatlas biochemistry entry for NUMBL:Drosophila numb homolog-like,signal transducer Eps15-2 of yeast,nematode homolog
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUMBL
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUMBL |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
NUMBL for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Numbltm1Wmz for NUMBL
10 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Numbl):
NUMBL for phenotypes About GeneDecksing
|
Pathways & Interactions
for NUMBL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Notch Signaling Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for NUMBL
1 
Kegg Pathway (Kegg details for NUMBL):
NUMBL for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUMBL
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/32 Interacting proteins for NUMBL (Q9Y6R01, 2, 3 ENSP000002528914) via UniProtKB, MINT, STRING, and/or I2D (see all 32)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| RBFOX1 | Q9NWB11, 2, 3, ENSP000003091174 | EBI-945925,EBI-1047634 MINT-2866238 MINT-2854978 I2D:
score=3 STRING: ENSP00000309117 | | ATXN1 | P542532, 3, ENSP000002447694 | MINT-2866257 I2D:
score=3 STRING: ENSP00000244769 | | EGFR | P005332, 3, ENSP000002754934 | MINT-74594 I2D:
score=1 STRING: ENSP00000275493 | | APP | P050673, ENSP000002849814 | I2D:
score=1 STRING: ENSP00000284981 | | LNX2 | Q8N4483, ENSP000003259294 | I2D:
score=1 STRING: ENSP00000325929 |
About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table
NUMBL for ontologies About GeneDecksing
|
Drugs & Compounds
for NUMBL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NUMBL
Search CenterWatch for drugs/clinical trials and news about NUMBL
|
Transcripts
for NUMBL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NUMBL gene: NM_004756.3 Unigene Cluster for NUMBL: Numb homolog (Drosophila)-like Hs.326953 [show with all ESTs]Unigene Representative Sequence: NM_0047562 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000252891(uc010xvq.2 uc002oon.3 uc002ooo.3 uc010xvr.2)
ENST00000540131
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUMBL (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUMBL
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NUMBL (NM_004756) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NUMBL | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUMBL |
Additional cDNA sequence: AF015041.1 AK096566.1 AK289398.1 AK299484.1 BC001794.1 BC144583.1 BT009807.1 U80758.1 9 DOTS entries: DT.95361052 DT.422730 DT.92424656 DT.92021038 DT.121458490 DT.75181753 DT.91911673 DT.75105988 DT.95155937 24/108 AceView cDNA sequences (see all 108): BU164698 AA280019 BF512426 BT009807 BQ184844 BQ187760 AI089522 AI286066 BU838127 BQ925542 CA776315 BI791777 AI360173 BQ720709 AW450233 CA776928 AI969852 BM805373 BQ883353 AI364030 BM848010 BI713549 BQ688168 AA280090
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for NUMBL About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NUMBL
|
Expression
for NUMBL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NUMBL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCGGTGCCCG
About this image
See NUMBL Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NUMBL
SOURCE GeneReport for Unigene cluster: Hs.326953
SABiosciences Custom PCR Arrays for NUMBL
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUMBL
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUMBL |
Orthologs
for NUMBL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for NUMBL gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Numbl1 , 5 |
numb-like1, 5 |
89.24(n)1
95.86(a)1 |
|
7 (15.86 cM)5
182231 NM_010950.21 NP_035080.21
272584335 |
lizard
(Anolis carolinensis) |
Reptilia |
NUMBL6 |
-- |
59(a) |
1 ↔ 1 |
LGf(2649888-2664751) |
zebrafish
(Danio rerio) |
Actinopterygii |
numbl1 |
numb homolog (Drosophila)-like |
65.82(n)
66.97(a) |
|
497616 NM_001012375.3 NP_001012375.3 |
fruit fly
(Drosophila melanogaster) |
Insecta |
numb3 |
N receptor signaling pathway protein binding |
56(a) |
|
30B5 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
num-16 |
Numb-related protein 1 |
23(a) |
1 → many |
V(20829780-20837521) |
ENSEMBL Gene Tree for NUMBL (if available)
TreeFam Gene Tree for NUMBL (if available) |
Paralogs
for NUMBL gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NUMBL gene
- NUMB2 GULP12 LDLRAP12
2 SIMAP similar genes for NUMBL using alignment to 6 protein entries: NUMBL_HUMAN (see all proteins):CTG3a NUMB
NUMBL for paralogs About GeneDecksing
|
Genomic Variants
for NUMBL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NUMBL (41171810 - 41196556 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for NUMBL
1 CNV: 58877
Human Gene Mutation Database (HGMD): NUMBL
| SABiosciences Cancer Mutation PCR Assays |
| 1 SABiosciences qBiomarker Copy Number PCR Array containing NUMBL: |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUMBL |
|
Disorders
/ Diseases
for NUMBL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NUMBL for disorders About GeneDecksing
OMIM gene information: 604018
OMIM disorders: --
5  diseases for NUMBL: About MalaCardstrichinosis neuroblastoma ataxia schizophrenia
neuronitis
1 disease from the University of Copenhagen DISEASES database for NUMBL:Neuroblastoma Human Genome Epidemiology (HuGE) Navigator: NUMBL (2 documents)
Export disorders for NUMBL gene to outside databases
|
Publications
for NUMBL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NUMBL gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with NUMBL) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module. (PubMed id 9303539)1, 2, 3 Salcini A.E....Di Fiore P.P. (1997)
- NUMBL interacts with TRAF6 and promotes the degradation of TRAF6. (PubMed id 20079715)1, 2 Zhou L.... Huo K. (2010)
- NUMBL interacts with TAB2 and inhibits TNFalpha and I L-1beta-induced NF-kappaB activation. (PubMed id 18299187)1, 2 Ma Q....Huo K. (2008)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- cDNAs with long CAG trinucleotide repeats from human brain. (PubMed id 9225980)1, 3 Margolis R.L.... Ross C.A. (1997)
- A genome-wide association study identifies three new r isk loci for Kawasaki disease. (PubMed id 22446962)1 Onouchi Y.... . (2012)
- Numbl inhibits glioma cell migration and invasion by s uppressing TRAF5-mediated NF-kB activation. (PubMed id 22593207)1 Tao T....Shen A. (2012)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Mutation and copy number analysis of LNX1 and Numbl in nervous system tumors. (PubMed id 18940473)1 Blom T....Nupponen N.N. (2008)
|
External Searches for NUMBL gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NUMBL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NUMBL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NUMBL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NUMBL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NUMBL gene:
Search GeneIP for patents involving NUMBL
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NUMBL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUMBL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUMBL | | | OriGene Protein Over-expression Lysate for NUMBL | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NUMBL | | OriGene 3'-UTR Clone for NUMBL | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUMBL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUMBL | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |  |  |  |  | | | | |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUMBL |
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