MORN4 Gene
protein-coding GIFtS : 41
GCID: GC10 M099365
MORN repeat containing 4 (Previous name: chromosome 10 open reading frame 83 ) (Previous symbol: C10orf83 )
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Aliasesfor MORN4 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases MORN Repeat Containing 4 1 2 Chromosome 10 Open Reading Frame 831 C10orf831 2 3 44050 Protein2 BA548K23.41 MORN Repeat-Containing Protein 42 Protein 440502 3 Retinophilin1 FLJ259251
Export aliases for MORN4 gene to outside databases Previous GC identifer: GC10M093000
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Summariesfor MORN4 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor MORN4 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000010.10 NC_018921.1 NT_030059.13 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the MORN4 gene promoter: RORalpha1 FOXO1a Sox9 Pax-4a FOXO1 Other transcription factors Search SABiosciences Chromatin IP Primers for MORN4 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat MORN4
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 10q24.2 Ensembl cytogenetic band: 10q24.2 HGNC cytogenetic band: 10q24.2 MORN4 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 10 GeneLoc Exon Structure
GeneLoc location for GC10M099365: view genomic region
(about GC identifiers )
Start:
99,374,310 bp from pter
End:
99,393,913 bp from pter
Size:
19,604 bases
Orientation:
minus strand
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Proteinsfor MORN4 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: MORN4_HUMAN, Q8NDC4 (See
protein sequence )Recommended Name: MORN repeat-containing protein 4 Size : 146 amino acids; 16236 Da
Secondary accessions : Q86Y54Alternative splicing : 2 isoforms : Q8NDC4-1 Q8NDC4-2 Explore the universe of human proteins at neXtProt for MORN4: NX_Q8NDC4 MORN4 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (2 alternative transcripts):
NP_001092301.1 NP_849154.1 ENSEMBL proteins: ENSP00000307636 ENSP00000441070 ENSP00000423222 ENSP00000359669 ENSP00000335498 Human Recombinant Protein Products: MORN4 Antibody Products: Assay Products for MORN4:
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Protein
Domains / Familiesfor MORN4 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
MORN4 for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q8NDC4 ProtoNet protein and cluster: Q8NDC4
UniProtKB/Swiss-Prot: MORN4_HUMAN, Q8NDC4 Similarity : Contains 4 MORN repeats
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Functionfor MORN4 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MORN4 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MORN4 (see all 3 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): MORN4 (NM_001098831 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MORN4 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MORN4
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MORN4
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Pathways & Interactionsfor MORN4 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MORN4 2 Interacting proteins for MORN4 (Q8NDC4 3 ) via UniProtKB, MINT, STRING, and/or I2D About this table
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Drugs & Compoundsfor MORN4 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for MORN4 Search CenterWatch for drugs/clinical trials and news about MORN4
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Transcriptsfor MORN4 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for MORN4 gene (2 alternative transcripts): NM_001098831.1 NM_178832.3 Unigene Cluster for MORN4:
MORN repeat containing 4 Hs.217409 [show with all ESTs ] Unigene Representative Sequence: NM_178832 5 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000307450 ENST00000478953 (uc001kod.4 ) ENST00000515674 (uc001koe.3 )ENST00000370635 (uc009xvv.1 ) ENST00000335628 (uc001kob.4 uc001koc.4 )Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MORN4 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MORN4 (see all 3 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): MORN4 (NM_001098831 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MORN4 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MORN4
Additional cDNA sequence: AJ312050.1 AJ431726.1 AK098791.1 AK289406.1 AL834132.1 BC010230.2 BC022054.1 BC040015.1 BC093023.1 DQ338435.1 DQ338436.1
5 DOTS entries : DT.91721938 DT.442751
DT.306535 DT.306536 DT.100740351 24/88 AceView cDNA sequences (see all 88 ):
BM126422 BU931819 AA885574 AJ431726 BU197109 BE551005 BM453881 NM_178832 AK098791 BX107861 CK819016 CB990425 AL834132 AA908763 CB961583 BC040015 AI300363 CF994060 AA340109 N59201 BX371969 AI291631 W56517 BE618478 GeneLoc Exon Structure 4 Alternative Splicing Database (ASD) splice patterns (SP) for MORN4 About this scheme ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c SP1 :   -   -     -             SP2 :         -             SP3 :       -   -     -         SP4 :                    
ECgene alternative splicing isoforms for MORN4
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Expression for MORN4 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section MORN4 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GCTGCAGGCT
About this image MORN4 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table 3 LifeMap In Vivo Development Anatomical Compartments/Cells Tissue Anatomical Compartment
Cell Category (developmental path) Gut Tube Midgut Midgut Endoderm Cells Endoderm Eye Retina Eye Gut Tube Midgut Gut Tube Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See MORN4 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for MORN4 SOURCE GeneReport for Unigene cluster: Hs.217409 SABiosciences Custom PCR Arrays for MORN4 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for MORN4Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat MORN4 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MORN4 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MORN4 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MORN4
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Orthologsfor MORN4 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for MORN4 gene from 6/24 species (see all 24 ) About this table
ENSEMBL Gene Tree for MORN4 (if available)TreeFam Gene Tree for MORN4 (if available)
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Paralogsfor MORN4 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for MORN4 gene JPH2 2 RSPH10B 2 JPH4 2 JPH1 2 ALS2CL 2 JPH3 2 RSPH10B2 2 MORN1 2 RSPH1 2 ALS2 2 MORN3 2 14 SIMAP similar genes for MORN4 using alignment to 3 protein entries: MORN4_HUMAN (see all proteins ):LOC118812 SETD7 ANKMY1 ALS2CL ALS2 MORN1 MORN3 RSPH10B RSPH1 RSPH10B2 DKFZp779I2251 JPH1 JPH2 JPH3
MORN4 for paralogs About GeneDecksing
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Genomic Variantsfor MORN4 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 10 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for MORN4 (99374310 - 99393913 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for MORN4: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing MORN4
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Disorders
/ Diseasesfor MORN4 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
MORN4 for disorders About GeneDecksing 2 diseases for MORN4 : About MalaCards pneumonia malaria 1 disease from the University of Copenhagen DISEASES database for MORN4 :Learning disability Export disorders for MORN4 gene to outside databases
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Publicationsfor MORN4 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for MORN4 gene integrated from 9 sources : (articles sorted by number of sources associating them with MORN4) Utopia : connect your pdf to the dynamic world of online information
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 , 3 Strausberg R.L....Marra M.A. (2002) Drosophila retinophilin contains MORN repeats and is conserved in humans. (PubMed id 17285308) 1 Mecklenburg K.L. (2007) The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005) 2 Bechtel S.... Schupp I. (2007) The LIFEdb database in 2006. (PubMed id 16381901) 1 Mehrle A....Wiemann S. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054) 2 Deloukas P.... Rogers J. (2004) From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336) 1 Wiemann S....Poustka A. (2004) Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166) 1 Wiemann S.... Poustka A. (2001) Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id ) 2 Aoki H.... Hino O. (2000) DNA cloning using in vitro site-specific recombination. (PubMed id 11076863) 1 Hartley J.L....Brasch M.A. (2000)
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External Searches for MORN4 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing MORN4 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing MORN4 gene
(According to HUGE )
About This Section --
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Specialized Databases showing MORN4 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for MORN4 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for MORN4 gene: Search GeneIP for patents involving MORN4 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor MORN4 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for MORN4 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for MORN4 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for MORN4 OriGene Protein Over-expression Lysate for MORN4 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for MORN4 OriGene 3'-UTR Clone for MORN4 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MORN4 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MORN4 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for MORN4 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for MORN4 OriGene Custom Protein Services for MORN4 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MORN4 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing MORN4 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat MORN4 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat MORN4 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MORN4 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MORN4
Search Tocris compounds for MORN4
MORN4 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MORN4
Search ThermoFisher Antibodies for MORN4
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MORN4
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