MADCAM1 Gene
protein-coding GIFtS: 56
GCID: GC19P000499
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|
mucosal vascular addressin cell adhesion molecule 1
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Aliases
for MADCAM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mucosal Vascular Addressin Cell Adhesion Molecule 11 2 | | MACAM11 2 5 | | MAdCAM-12 3 | | HMAdCAM-11 | | Mucosal Addressin Cell Adhesion Molecule 12 | | Mucosal Addressin Cell Adhesion Molecule-12 |
Export aliases for MADCAM1 gene to outside databasesPrevious GC identifers: GC19P000507 GC19P000531 GC19P000436 GC19P000448 GC19P000449 GC19P000450 GC19P000266 |
Summaries
for MADCAM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MADCAM1:
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with theleukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to directleukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 andVCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for thisgene, but the full-length nature of some variants has not been determined. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477Function: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic intomucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrinalpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking themucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening,independent of L-selectin binding
Gene Wiki entry for MADCAM1 (Addressin)
|
Genomic Views
for MADCAM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MADCAM1 gene promoter:
Tal-1 COUP Tal-1beta E47 POU2F1 COUP-TF POU2F1a STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for MADCAM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MADCAM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3MADCAM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P000499: view genomic region
(about GC identifiers)
Start:
|
489,176 bp from pter |
End:
|
505,347 bp from pter |
Size:
|
16,172 bases |
Orientation:
|
plus strand |
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Proteins
for MADCAM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477 (See
protein sequence)Recommended Name: Mucosal addressin cell adhesion molecule 1 precursor Size: 382 amino acids; 40155 Da
Subunit: Homodimer (Probable)
Subcellular location: Membrane; Single-pass type I membrane protein
6 PDB 3D structures from  and Proteopedia  for MADCAM1:1BQS (3D)
1GSM (3D)
4HBQ (3D)
4HC1 (3D)
4HCR (3D)
4HD9 (3D)
Secondary accessions: A5PKV4 B2RPL9 O60222 O75867Alternative splicing: 3 isoforms: Q13477-1 Q13477-2 Q13477-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MADCAM1: NX_Q13477
Post-translational modifications:
The Ser/Thr-rich mucin-like domain may provide possible sites for O-glycosylation (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13477
MADCAM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_570116.2 NP_570118.1
ENSEMBL proteins: ENSP00000304247 ENSP00000215637 ENSP00000372130 Reactome Protein details: Q13477
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
MADCAM1 for ontologies About GeneDecksing
MADCAM1 Antibody Products:
Assay Products for MADCAM1: |
Protein
Domains /
Families
for MADCAM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MADCAM1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13477ProtoNet protein and cluster: Q13477 1 Blocks protein family: IPB003599 Immunoglobulin subtype
UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477Similarity: Contains 2 Ig-like (immunoglobulin-like) domains |
Function
for MADCAM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477Function: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic intomucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrinalpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking themucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening,independent of L-selectin binding Genatlas biochemistry entry for MADCAM1:mucosal vascular addressin cell adhesion molecule 1,ligand for leukocyte B7 integrin (LPAM-1) L selectin,VLA-4 onmyeloid cells,with two alternatively spliced forms,homing leukocytes to mucosal inflammed tissues
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MADCAM1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MADCAM1 |
Animal Models:
Mouse knock-out Madcam1tm1.2Nwag for MADCAM1
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Madcam1):
MADCAM1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MADCAM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Immune System | | | 2 | Cell adhesion molecules (CAMs) | | | 3 | Paxillin-independent events mediated by a4b1 and a4b7 | | | 4 | Signaling by GPCR | | | 5 | Allograft rejection | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for MADCAM1
5 
Reactome Pathways for MADCAM1
2 
Kegg Pathways (Kegg details for MADCAM1):
MADCAM1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MADCAM1
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
4 Interacting proteins for MADCAM1 (Q134773 ENSP000002156374) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
MADCAM1 for ontologies About GeneDecksing
|
Drugs & Compounds
for MADCAM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MADCAM1 for compounds About GeneDecksing
 Browse Tocris compounds for MADCAM1
9 Novoseek chemical compound relationships for MADCAM1 gene About this table
Search CenterWatch for drugs/clinical trials and news about MADCAM1 / MADCA
|
Transcripts
for MADCAM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MADCAM1 gene (2 alternative transcripts): NM_130760.2 NM_130762.2 Unigene Cluster for MADCAM1: Mucosal vascular addressin cell adhesion molecule 1 Hs.102598 [show with all ESTs]Unigene Representative Sequence: AK0922114 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000587541 ENST00000346144(uc002lot.3 uc010drq.3) ENST00000215637(uc002los.3)
ENST00000382683
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MADCAM1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MADCAM1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): MADCAM1 (NM_130762) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MADCAM1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MADCAM1 |
Additional cDNA sequence: AK092211.1 AY732484.1 AY819760.1 BC136408.1 BC137506.1 BC137507.1 BC142629.1 BC144065.1 DQ076657.1 U43628.1 U82483.1 4 DOTS entries: DT.409211 DT.92360074 DT.99932820 DT.99965995 18 AceView cDNA sequences: NM_130762 AA678836 AA928768 BI821776 AW340299 NM_130760 AI131233 U82483 BM702750 U43628 AK092211 NM_130761 AA705935 AA668527 AW340202 T54621 BE173884 T54705
GeneLoc Exon Structure
|
Expression
for MADCAM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MADCAM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTCACGTCT
About this image
See MADCAM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MADCAM1
SOURCE GeneReport for Unigene cluster: Hs.102598
UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477Tissue specificity: Highly expressed on high endothelial venules (HEV) and lamina propia venules found in the smallintestine, and to a lesser extent in the colon and spleen. Very low levels of expression found in pancreas and brain.Not expressed in the thymus, prostate, ovaries, testis, heart, placenta, lung, liver, skeletal muscle, kidney orperipheral blood leukocytes
SABiosciences Custom PCR Arrays for MADCAM1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MADCAM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MADCAM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MADCAM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MADCAM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MADCAM1 |
Orthologs
for MADCAM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for MADCAM1 gene from 2/7 species (see all 7) About this table
ENSEMBL Gene Tree for MADCAM1 (if available)
TreeFam Gene Tree for MADCAM1 (if available) |
Paralogs
for MADCAM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MADCAM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477Polymorphism: The number of repeats in the mucin domain varies between 5 and 8 repeats
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MADCAM1 (489176 - 505347 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for MADCAM1
5 CNVs: 7203 50140 67427 30050 73264
1 Indel: 73260 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MADCAM1 |
|
Disorders
/ Diseases
for MADCAM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MADCAM1 for disorders About GeneDecksing
OMIM gene information: 102670
OMIM disorders: --
20/30  diseases for MADCAM1 (see all 30): About MalaCardssclerosing cholangitis primary sclerosing cholangitis malt lymphoma inflammatory bowel disease
cholangitis acquired immunodeficiency syndrome adult t-cell leukemia leukemia/lymphoma
ulcerative colitis liver disease cholera celiac disease
t-cell leukemia jaundice periodontitis periodontal disease
crohn's disease encephalomyelitis gastritis duodenitis
1 disease from the University of Copenhagen DISEASES database for MADCAM1:Inflammatory bowel disease 10/16 Novoseek disease relationships for MADCAM1 gene (see all 16) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| inflammatory bowel diseases |
68.6 |
21 |
11472325 (5), 10562584 (2), 11343233 (2), 11481030 (1) (see all 9) |
| colitis |
50 |
5 |
16917232 (2), 12625840 (1), 19847949 (1) |
| ileitis |
45.1 |
3 |
16401463 (2), 15699171 (1) |
| inflammation |
44 |
20 |
10661685 (2), 9036954 (2), 16401463 (2), 10562584 (1) (see all 12) |
| cholangitis primary sclerosing |
41.8 |
6 |
11343233 (3), 16750586 (2), 19233184 (1) |
| malt lymphoma |
40.6 |
2 |
11504840 (1), 14669317 (1) |
| lymphoma low-grade |
38.9 |
1 |
11504840 (1) |
| lymphoma t-cell |
38.7 |
1 |
10508262 (1) |
| colitis ulcerative |
34.7 |
4 |
9212736 (1), 19847949 (1), 19067429 (1), 9214052 (1) |
| lymphoma |
29.7 |
2 |
7517418 (1), 7687523 (1) |
Human Genome Epidemiology (HuGE) Navigator: MADCAM1 (2 documents)
Export disorders for MADCAM1 gene to outside databases
|
Publications
for MADCAM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MADCAM1 gene, integrated from 9 sources (see all 139):
(articles sorted by number of sources associating them with MADCAM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences. (PubMed id 8609404)1, 2, 3, 9 Shyjan A.M.... Briskin M.J. (1996)
- Genomic organization, chromosomal mapping, and analysis of the 5' promoter region of the human MAdCAM-1 gene. (PubMed id 9162097)1, 2, 3, 9 Leung E.... Krissansen G.W. (1997)
- The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition. (PubMed id 9655832)1, 2, 9 Tan K....Wang J.H. (1998)
- A reassessment of the MAdCAM-1 structure and its role in integrin recognition. (PubMed id 11807247)1, 2, 9 Dando J.... Brady R.L. (2002)
- Cloning of the mucosal addressin MAdCAM-1 from human brain: identification of novel alternatively spliced transcripts. (PubMed id 8989586)1, 2, 9 Leung E....Krissansen G.W. (1996)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. (PubMed id 15483224)1, 9 Ogawa H....Rafiee P. (2005)
- Structure-function analysis of the integrin beta 7 subunit: identification of domains involved in adhesion to MAdCAM-1. (PubMed id 9233649)1, 9 Tidswell M....Erle D.J. (1997)
- Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. (PubMed id 9212736)1, 9 Briskin M....Ringler D.J. (1997)
- CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow. (PubMed id 18308860)1, 9 Miles A....Adams D.H. (2008)
|
External Searches for MADCAM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MADCAM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MADCAM1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MADCAM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MADCAM1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MADCAM1 gene:
Search GeneIP for patents involving MADCAM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MADCAM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for MADCAM1 | | OriGene shRNA RFP for MADCAM1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MADCAM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MADCAM1 | | | OriGene Protein Over-expression Lysate for MADCAM1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MADCAM1 | | OriGene 3'-UTR Clone for MADCAM1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MADCAM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MADCAM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MADCAM1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MADCAM1 | | OriGene Custom Protein Services for MADCAM1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MADCAM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MADCAM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MADCAM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MADCAM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MADCAM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MADCAM1 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MADCAM1 |
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