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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

JMJD7-PLA2G4B Gene

protein-coding GIFtS: 51
GCID: GC15P042122

JMJD7-PLA2G4B readthrough

Explore 5 diseases affiliated with
JMJD7-PLA2G4B via

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
JMJD7-PLA2G4B Readthrough¹ ²		JMJD7-PLA2G4B Protein²
CPLA2-Beta¹		Jumonji Domain Containing 7-Phospholipase A2, Group IVB (Cytosolic) Read-Through²
EC 3.1.1.4³ ⁸		Phospholipase A2 Group IVB³
HsT16992²

External Ids:	HGNC: 34449¹	Entrez Gene: 8681²	Ensembl: ENSG00000168970⁷	UniProtKB: P0C869³

Export aliases for JMJD7-PLA2G4B gene to outside databases

Previous GC identifers: GC15P039910 GC15P018968

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for JMJD7-PLA2G4B:

This gene transcribes naturally-occurring mRNAs that are read-through products of the neighboring jumonji domain

containing 7 (JMJD7) and phospholipase A2, group IVB (PLA2G4B) genes. These read-through products contain in-frame

segments from both genes but a function has yet to be determined for the predicted fusion proteins, which contain a

partial JmjC domain and downstream C2 and phospholipase A2 domains. Alternatively spliced transcript variants have

been observed for this gene. (provided by RefSeq, Sep 2011)

UniProtKB/Swiss-Prot: PA24B_HUMAN, P0C869

Function: Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position with

a preference for arachidonoyl phospholipids. Has a much weaker activity than PLA2G4A. Isoform 3 has calcium-dependent

activity against palmitoyl-arachidonyl-phosphatidylethanolamine and low level lysophospholipase activity but no

activity against phosphatidylcholine. Isoform 5 does have activity against phosphatidylcholine

Gene Wiki entry for JMJD7-PLA2G4B (PLA2G4B)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000015.9 NC_018926.1 NT_010194.17

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for JMJD7-PLA2G4B
Other transcription factors

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Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat JMJD7-PLA2G4B

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q11.2-q21.3 Ensembl cytogenetic band: 15q15.1 HGNC cytogenetic band: 15q11.2-q21.3

JMJD7-PLA2G4B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
JMJD7-PLA2G4B gene location

GeneLoc information about chromosome 15 GeneLoc Exon Structure

GeneLoc location for GC15P042122: view genomic region (about GC identifiers)

Start:	42,120,283 bp from pter	End:	42,140,353 bp from pter
Size:	20,071 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PA24B_HUMAN, P0C869 (See protein sequence)

Recommended Name: Cytosolic phospholipase A2 beta

Size: 781 amino acids; 87978 Da

Subcellular location: Cytoplasm, cytosol

Subcellular location: Isoform 3: Mitochondrion membrane; Peripheral membrane protein. Early endosome membrane;

Peripheral membrane protein. Note=Translocates to membrane vesicles in a calcium-dependent fashion

Caution: Most tissues also express read-through transcripts from this gene into the upstream gene (JMJD7), some of

which may encode fusion proteins

Sequence caution: Sequence=BAD92387.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Secondary accessions: B4DRT9 O95712 Q19KD5 Q19KD6 Q59GF9 Q8TB10 Q9UKV7

Alternative splicing: 5 isoforms: P0C869-1, O95712-1 P0C869-7 P0C869-8 P0C869-4, O95712-4 P0C869-6 (Based on a naturally occurring readthrough transcript which produces a JMJD7-PLA2G4B fusion protein)

Explore the universe of human proteins at neXtProt for JMJD7-PLA2G4B: NX_P0C869

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P0C869

2 DME Specific Peptides for JMJD7-PLA2G4B (P0C869)

RAMTSLYG

EFSPYEVG

JMJD7-PLA2G4B Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001185517.1 NP_005081.1

ENSEMBL proteins:

ENSP00000371886 ENSP00000342785 ENSP00000424127 ENSP00000441905 ENSP00000416610

Reactome Protein details: P0C869
Human Recombinant Protein Products:

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Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	--	--
GO:0005829	cytosol	--	--
GO:0031901	early endosome membrane	--	--
GO:0031966	mitochondrial membrane	--	--

JMJD7-PLA2G4B for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

JMJD7-PLA2G4B for domains About GeneDecksing

5 InterPro domains/families:

IPR016035 Acyl_Trfase/lysoPLipase

IPR008973 C2_Ca/lipid-bd_dom_CaLB

IPR002642 LysoPLipase_cat_dom

IPR018029 C2_membr_targeting

IPR000008 C2_Ca-dep

Graphical View of Domain Structure for InterPro Entry P0C869

ProtoNet protein and cluster: P0C869

UniProtKB/Swiss-Prot: PA24B_HUMAN, P0C869

Domain: The N-terminal C2 domain associates with lipid membranes upon calcium binding. It modulates enzyme activity by

presenting the active site to its substrate in response to elevations of cytosolic Ca(2+) (By similarity)

Similarity: Contains 1 C2 domain

Similarity: Contains 1 PLA2c domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: PA24B_HUMAN, P0C869

Function: Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position with

a preference for arachidonoyl phospholipids. Has a much weaker activity than PLA2G4A. Isoform 3 has calcium-dependent

activity against palmitoyl-arachidonyl-phosphatidylethanolamine and low level lysophospholipase activity but no

activity against phosphatidylcholine. Isoform 5 does have activity against phosphatidylcholine

Catalytic activity: Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate

Enzyme regulation: Stimulated by cytosolic Ca(2+)

Biophysicochemical properties: Kinetic parameters: Vmax=7.9 pmol/min/mg enzyme (isoform 5); Vmax=3.6 pmol/min/ug enzyme

with cAMP as substrate (isoform 4); Vmax=140 nmol/min/ug enzyme with 1-[14C]16:0-2-lyso-PC as substrate (isoform 5);

Vmax=1.6 nmol/min/ug enzyme with 1-[14C]16:0-2-lyso-PC as substrate (isoform 3); Vmax=2.1 nmol/min/ug enzyme with

1-16:0-2-[14C]20:4-PC as substrate (isoform 5); Vmax=0.6 nmol/min/ug enzyme with 1-16:0-2-[14C]20:4-PE as substrate

(isoform 5); Vmax=0.8 nmol/min/ug enzyme with 1-16:0-2-[14C]20:4-PE as substrate (isoform 3); Vmax=0.3 nmol/min/ug

enzyme with 1-16:0-2-[14C]18:2-PE as substrate (isoform 3);

Enzyme Number (IUBMB): EC 3.1.1.4¹ ²

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Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004622	lysophospholipase activity	--	--
GO:0005509	calcium ion binding	--	--
GO:0005544	calcium-dependent phospholipid binding	--	--
GO:0047498	calcium-dependent phospholipase A2 activity	--	--

JMJD7-PLA2G4B for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for JMJD7-PLA2G4B:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

alpha-Linolenic acid metabolism

	alpha-Linolenic acid metabolism	1.00			Ether lipid metabolism	0.44
	Linoleic acid metabolism	0.52			Fat digestion and absorption	0.32

GnRH signaling pathway

GnRH signaling pathway

1.00

Vascular smooth muscle contraction

0.36

VEGF signaling pathway

VEGF signaling pathway

1.00

Fc epsilon RI signaling pathway

0.42

Pancreatic secretion

Pancreatic secretion

1.00

Long-term depression

Long-term depression

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

5/15 Reactome Pathways for JMJD7-PLA2G4B (see all 15)

	Acyl chain remodelling of PE
	Synthesis of PA
	Metabolism
	Acyl chain remodelling of PC
	Acyl chain remodelling of PG

5/16 Kegg Pathways (Kegg details for JMJD7-PLA2G4B) (see all 16):

	Glycerophospholipid metabolism
	Ether lipid metabolism
	Arachidonic acid metabolism
	Linoleic acid metabolism
	alpha-Linolenic acid metabolism

JMJD7-PLA2G4B for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for JMJD7-PLA2G4B

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/69 Interacting proteins for JMJD7-PLA2G4B (P0C869³ ENSP00000371886⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 69)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SHBG	P04278³, ENSP00000369816⁴	I2D: score=2 STRING: ENSP00000369816
LYPLA1	ENSP00000320043⁴	STRING: ENSP00000320043
PLA2G7	ENSP00000274793⁴	STRING: ENSP00000274793
PLB1	ENSP00000330442⁴	STRING: ENSP00000330442
PTGS1	ENSP00000354612⁴	STRING: ENSP00000354612

About this table

Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006954	inflammatory response	--	--
GO:0006987	activation of signaling protein activity involved in unfolded protein response	--	--
GO:0007567	parturition	--	--
GO:0019369	arachidonic acid metabolic process	--	--
GO:0019722	calcium-mediated signaling	--	--

JMJD7-PLA2G4B for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

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Search CenterWatch for drugs/clinical trials and news about JMJD7-PLA2G4B / PA24B

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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About This Section

REFSEQ mRNAs for JMJD7-PLA2G4B gene (2 alternative transcripts):

NM_001198588.1 NM_005090.3

Unigene Cluster for JMJD7-PLA2G4B:

JMJD7-PLA2G4B readthrough

Hs.198161 [show with all ESTs]

Unigene Representative Sequence: BX648318

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000490848(uc001zon.2 uc001zoo.4 uc010bcn.3 uc001zoq.4 uc010bco.3)

ENST00000382448 ENST00000491746 ENST00000342159 ENST00000476036 ENST00000487292

ENST00000542534 ENST00000458483

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Additional cDNA sequence:

AK000550.1 AK000663.1 AK000814.1 AK225503.1 AK289833.1 AK290051.1 AK299419.1 BC025290.1

BC067834.1 BC110415.1 BC128426.1 BC139899.1 BX648318.1

18 DOTS entries:

DT.97842266 DT.311958 DT.101984110 DT.95261647 DT.100778046 DT.95237468 DT.121643035 DT.95367714

DT.100684154 DT.95305313 DT.121078144 DT.97839699 DT.100024908 DT.100024910 DT.121078181 DT.40292354

DT.95257992 DT.97822446

24/147 AceView cDNA sequences (see all 147):

BM712481 BI488527 AL134221 BM715074 BC013415 BM856492 BM018609 Z39200

CB306001 BM672804 CD106612 BI040640 AU106339 NM_005090 CA488226 BU556751

BM982475 AF065215 BU557386 BQ959906 CA313879 BI040647 BC025290 BP368732

GeneLoc Exon Structure

5/20 Alternative Splicing Database (ASD) splice patterns (SP) for JMJD7-PLA2G4B (see all 20) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	·	5c	·	5d	·	5e	^	6	^	7	^	8a	·	8b	·	8c	^	9	^	10	^	11a	·	11b	·	11c	·	11d	^	12	^	13a	·	13b	^	14a	·	14b	·
SP1:					-		-								-										-								-		-		-		-		-		-		-		-		-		-
SP2:																																									-		-		-		-		-
SP3:					-						-				-		-								-
SP4:					-		-								-										-
SP5:

ExUns:	14c	^	15	^	16a	·	16b	·	16c	·	16d	^	17	^	18	^	19	^	20	^	21a	·	21b	^	22	^	23a	·	23b	^	24a	·	24b	^	25	^	26	^	27a	·	27b	^	28	^	29a	·	29b	^	30a	·	30b	^
SP1:																							-				-		-		-														-
SP2:																							-		-		-		-		-														-
SP3:
SP4:
SP5:																																													-

ExUns:	31a	·	31b	^	32	^	33a	·	33b
SP1:
SP2:
SP3:
SP4:
SP5:	-

ECgene alternative splicing isoforms for JMJD7-PLA2G4B

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

JMJD7-PLA2G4B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGAATAAAA

About this image
See JMJD7-PLA2G4B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for JMJD7-PLA2G4B

SOURCE GeneReport for Unigene cluster: Hs.198161

UniProtKB/Swiss-Prot: PA24B_HUMAN, P0C869

Tissue specificity: Widely expressed. Expressed at higher level in brain, heart, liver, cerebellum and pancreas.

Isoform 3 is widely expressed

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for JMJD7-PLA2G4B gene from 3/6 species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	JMJD7⁶ PLA2G4E⁶	Uncharacterized protein	52(a) 43(a)	1 ↔ many possible ortholog	5(27300442-27359905) 5(27675765-27690864)
lizard (Anolis carolinensis)	Reptilia	-- --	--	46(a) 42(a)	1 ↔ many possible ortholog	1(40700407-40743498) 1(40793049-40829512)
zebrafish (Danio rerio)	Actinopterygii	BX927351.2⁶ BX927351.1⁶	--	34(a) 33(a)	many ↔ many many ↔ many	17(21312011-21323974) 17(21283452-21297200)

ENSEMBL Gene Tree for JMJD7-PLA2G4B (if available)
TreeFam Gene Tree for JMJD7-PLA2G4B (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for JMJD7-PLA2G4B gene

PLA2G4A² PLA2G4D² PLA2G4B² PLA2G4F² PLA2G4E² PLA2G4C²

2 SIMAP similar genes for JMJD7-PLA2G4B using alignment to 1 protein entry: H0Y9G9_HUMAN:

JMJD7 HIF1AN

JMJD7-PLA2G4B for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
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SNP ID	Valid	Clinical significance	Chr 15 pos	Sequence	#	AA Chg	Type	More	#	Pop	Total sample
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs3743025^1,2	C,H	--	18967006(-)	`ATGTGT/GGCACG`	2	--	us2k¹		8	EA NA NS	2034
rs61046109^1,2	F,	--	18967071(+)	`ATCTGG/ACTGGC`	2	--	us2k¹		1	WA	118
rs8039561^1,2	C,F,H,	--	18967220(+)	`TGATAC/TGAGAT`	2	--	us2k¹		5	NS EA WA	496
rs114118341^1,2	C,F,	--	18967372(+)	`GGTAAG/ATGGCA`	2	--	us2k¹		1	WA	118
rs4923914^1,2	C,F,A,H,	--	18967992(+)	`AGCATC/TGCYAC`	2	--	us2k¹		8	NS EA NA	654
rs4923915^1,2	C,A,	--	18967995(+)	`ATYGCC/TACCCG`	2	--	us2k¹		3	NA EA	242
rs114261007^1,2	C,F,	--	18968129(+)	`AGGAGG/AGAGCT`	2	--	us2k¹		1	WA	118
rs2277534^1,2	C,F,H,	--	18968226(-)	`GGGACG/AGGGCG`	2	--	us2k¹		4	NS EA	416
rs8025714^1,2	C,F,	--	18968546(+)	`ggcggG/Cgtgct`	2	--	us2k¹		5	NA EA	246
rs13380315^1,2	C,F,	--	18968826(+)	`NNNNCC/GTGGGA`	2	--	int¹		8	NA WA CSA EA	368

HapMap Linkage Disequilibrium report for JMJD7-PLA2G4B (42120283 - 42140353 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for JMJD7-PLA2G4B
3 CNVs: 49553 3078 30707

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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JMJD7-PLA2G4B for disorders About GeneDecksing

5 diseases for JMJD7-PLA2G4B: About MalaCards

toxoplasmosis schizophrenia pancreatitis prostatitis

neuronitis

Human Genome Epidemiology (HuGE) Navigator: JMJD7-PLA2G4B (0 documents)

Export disorders for JMJD7-PLA2G4B gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for JMJD7-PLA2G4B gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with JMJD7-PLA2G4B)

Utopia: connect your pdf to the dynamic
world of online information

Identification of the expressed form of human cytosolic phospholipase A2beta (cPLA2beta): cPLA2beta3 is a novel variant localized to mitochondria and early endosomes. (PubMed id 16617059)^{1, 2, 9} Ghosh M.... Leslie C.C. (2006)
Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2. (PubMed id 10085124)^{1, 2} Pickard R.T.... Sharp J.D. (1999)
Molecular characterization of cytosolic phospholipase A2-beta. (PubMed id 10358058)^{1, 2} Song C.... Kriz R.W. (1999)
Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)¹ Prakash T....Taylor T.D. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)² Zody M.C....Nusbaum C. (2006)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
Cytosolic PLA2 genes possibly contribute to the etiology of schizophrenia. (PubMed id 15999343)¹ Tao R....Wei J. (2005)
Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin. (PubMed id 15862967)¹ Pope S.N. and Lee I.R. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 8681	HGNC: 34449	AceView: PLA2G4B	Ensembl:ENSG00000168970	euGenes: HUgn8681
ECgene: JMJD7-PLA2G4B	Kegg: 8681	H-InvDB: JMJD7-PLA2G4B

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for JMJD7-PLA2G4B	Pharmacogenomics, SNPs, Pathways

Intellectual Property for JMJD7-PLA2G4B gene
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Patent Information for JMJD7-PLA2G4B gene:
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