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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ITGAD Gene

protein-coding   GIFtS: 56
GCID: GC16P031405

integrin, alpha D

 Explore 5 diseases affiliated with
ITGAD via our new
 Human Malady Compendium 
Biological research products
for ITGAD
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Integrin, Alpha D1 2     CD11D2 5
ADB21 2 3     CD11d1
Leukointegrin Alpha D2 3     Integrin Alpha-D2
CD11 Antigen-Like Family Member D2 3     CD11d Antigen3

External Ids:    HGNC: 61461   Entrez Gene: 36812   Ensembl: ENSG000001568867   OMIM: 6024535   UniProtKB: Q133493   

Export aliases for ITGAD gene to outside databases

Previous GC identifers: GC16U990033 GC16P031901 GC16P031401 GC16P031440 GC16P031312 GC16P028964


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ITAD_HUMAN, Q13349
Function: Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process
such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and
senescent erythrocytes from the blood

Gene Wiki entry for ITGAD


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ITGAD gene promoter:
         AhR   ER-alpha   RP58   Elk-1   p53   CUTL1   LCR-F1   Ik-3   Arnt   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidITGAD promoter sequence
   Search SABiosciences Chromatin IP Primers for ITGAD

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITGAD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p13.1-p11

ITGAD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ITGAD gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P031405:  view genomic region     (about GC identifiers)

Start:
31,404,633 bp from pter      End:
31,437,826 bp from pter
Size:
33,194 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ITAD_HUMAN, Q13349 (See protein sequence)
Recommended Name: Integrin alpha-D precursor  
Size: 1161 amino acids; 126758 Da
Subunit: Heterodimer of an alpha and a beta subunit. Alpha-D associates with beta-2
Subcellular location: Membrane; Single-pass type I membrane protein
Sequence caution: Sequence=AAB60634.1; Type=Miscellaneous discrepancy;
Secondary accessions: Q15575 Q15576

Explore the universe of human proteins at neXtProt for ITGAD: NX_Q13349

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13349

  • ITGAD Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005344.2  
    ENSEMBL proteins: 
     ENSP00000373854  
    Reactome Protein details: Q13349
    Human Recombinant Protein Products: 
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    Novus Biologicals ITGAD Protein
    Novus Biologicals ITGAD Lysate
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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0008305integrin complex TAS--


    ITGAD for ontologies           About GeneDecksing



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    Browse ELISAs and CLIAs at Uscn


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ITGAD for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR000413 Integrin_alpha
     IPR013519 Int_alpha_beta-p
     IPR018184 Integrin_alpha_C_CS
     IPR013649 Integrin_alpha-2
     IPR002035 VWF_A

    Graphical View of Domain Structure for InterPro Entry Q13349

    ProtoNet protein and cluster: Q13349

    4 Blocks protein families:
    IPB000413 Integrins alpha chain
    IPB002035 Von Willebrand factor type A domain signature
    IPB013513 Integrin alpha chain
    IPB013517 FG-GAP


    UniProtKB/Swiss-Prot: ITAD_HUMAN, Q13349
    Domain: The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage
    Similarity: Belongs to the integrin alpha chain family
    Similarity: Contains 7 FG-GAP repeats
    Similarity: Contains 1 VWFA domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ITAD_HUMAN, Q13349
    Function: Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process
    such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and
    senescent erythrocytes from the blood

         Genatlas biochemistry entry for ITGAD:
    integrin,alpha D,cell surface adhesion receptor mediating cell-adhesion to extra cellular matrix or to other
    cells,through hetero dimerization and connecting to the cytoskeleton and various signaling molecules within
    cells,arrayed in tandem with ITGAX (CD11C),dimerizing with ITGB2 in fibrinogen,C3b receptor

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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITGAD

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity ----
    GO:0046872metal ion binding IEA--
    GO:0046982protein heterodimerization activity ----


    ITGAD for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for ITGAD: Itgadtm1Bll Itgadtm1.1Zimm
         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Itgad):
     cellular  hematopoietic system  homeostasis/metabolism  immune system 

    ITGAD for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/19 super-pathways (see all 19About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Integrin Pathway
    Integrin Pathway1.00
    UPA-UPAR Pathway0.51
    FAK1 Signaling0.67
    Transendothelial Migration of Leukocytes0.38
    GnRH Signaling0.56
    2Rho Family GTPases
    Rho Family GTPases1.00
    MAPK Signaling0.51
    ERK Signaling0.61
    ILK Signaling0.45
    Molecular Mechanisms of Cancer0.51
    3Apoptotic Pathways in Synovial Fibroblasts
    PPAR Pathway0.66
    Actin-Based Motility by Rho Family GTPases0.52
    Rac1 Pathway0.58
    Rap1 Pathway0.42
    Glioma Invasiveness0.54
    4Actin Nucleation by ARP-WASP Complex
    Actin Nucleation by ARP-WASP Complex1.00
    RhoA Pathway0.35
    Actin Nucleation and Branching0.66
    CDC42 Pathway0.34
    5Focal Adhesion
    Focal Adhesion1.00
    HGF Pathway0.24
    Integrin-mediated cell adhesion0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/35 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ITGAD (see all 35)
        RhoA Pathway
    Paxillin Interactions
    Molecular Mechanisms of Cancer
    CDK5 Pathway
    Tec Kinases Signaling

    2 BioSystems Pathways for ITGAD 
        Integrin-mediated cell adhesion
    Focal Adhesion

    2        Reactome Pathways for ITGAD
        Integrin cell surface interactions
    Signal Transduction


    1         Kegg Pathway  (Kegg details for ITGAD):
        Regulation of actin cytoskeleton


    ITGAD for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ITGAD

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/38 Interacting proteins for ITGAD (Q133493 ENSP000003738544) via UniProtKB, MINT, STRING, and/or I2D (see all 38)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ITGB2P051073, ENSP000003032424I2D: score=4 STRING: ENSP00000303242
    ICAM3P329423, ENSP000001602624I2D: score=3 STRING: ENSP00000160262
    VCAM1P193203, ENSP000002947284I2D: score=3 STRING: ENSP00000294728
    VTNP040043I2D: score=1 
    FGAENSP000003063614STRING: ENSP00000306361
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response NAS9841932
    GO:0007160cell-matrix adhesion NAS--
    GO:0007229integrin-mediated signaling pathway IEA--
    GO:0016337cell-cell adhesion NAS--
    GO:0050798activated T cell proliferation IEA--


    ITGAD for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ITGAD
    Search CenterWatch for drugs/clinical trials and news about ITGAD / ITAD 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ITGAD gene: 
    NM_005353.2  

    Unigene Cluster for ITGAD:

    Integrin, alpha D
    Hs.679163  [show with all ESTs]
    Unigene Representative Sequence: AB208945
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389202(uc002ebv.1 uc010cap.1) ENST00000444228(uc010vfl.1 uc002ebw.1)
    ENST00000567308

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    Additional cDNA sequence: 

    AB208945.1 AK097160.1 AK125016.1 AK301028.1 U37028.1 

    4 DOTS entries:

    DT.92000497  DT.99934184  DT.101958707  DT.95143139 

    3 AceView cDNA sequences:

    U37028 AK097160 BQ711865 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ITGAD    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^
    SP1:                                                                                -                                                                           
    SP2:                                                                                -                                                                           
    SP3:                          -     -                 -                                                                                                         

    ExUns: 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30a · 30b
    SP1:                                                      
    SP2:                                                      
    SP3:                                                      


    ECgene alternative splicing isoforms for ITGAD

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ITGAD expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAATGAGGAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ITGAD Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ITGAD

    SOURCE GeneReport for Unigene cluster: Hs.679163

    UniProtKB/Swiss-Prot: ITAD_HUMAN, Q13349
    Tissue specificity: Expressed moderately on myelomonocytic cell lines and subsets of peripheral blood leukocytes and
    strongly on tissue-specialized cells, including macrophages foam cells within atherosclerotic plaques, and on splenic
    red pulp macrophages

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITGAD

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ITGAD gene from 3/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    --
    46(a)
    44(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    GL343220.1(2391221-2422669)
    GL343220.1(2431120-2468441)
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-32n7.46
    si:dkey-32n7.4
    36(a)
    1 → many
    12(4794914-4825546)
    fruit fly
    (Drosophila melanogaster)
    Insecta alphaPS56
    alphaPS46
    (see all 3)
    alphaPS4
    (see all 3)
    18(a)
    17(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    2R(19444333-19447720)
    2R(11146272-11150371)


    ENSEMBL Gene Tree for ITGAD (if available)
    TreeFam Gene Tree for ITGAD (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ITGAD gene
    ITGA12  ITGA62  ITGA32  ITGA72  ITGA82  ITGAM2  ITGA112  ITGA22  
    ITGA52  ITGAE2  ITGA2B2  ITGAV2  ITGAX2  ITGAL2  ITGA92  ITGA42  
    ITGA102  
    4 SIMAP similar genes for ITGAD using alignment to 1 protein entry:     ITAD_HUMAN:
    ITGAX    ITGAM    FLJ00114    ITGAL

    ITGAD for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/672 NCBI SNPs in ITGAD are shown (see all 672    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1488744351,2
    --31402931(+) CTCCCA/TAAGTG 1 -- us2k10--------
    rs1898517801,2
    --31403063(+) TTCCTA/GAGCTT 1 -- us2k10--------
    rs129324291,2
    C,--31403145(+) AATCTC/TGACTC 1 -- us2k1 tfbs36Minor allele frequency- T:0.00NA WA CSA 11
    rs1510644641,2
    --31403275(+) TTTCAA/CCATAT 1 -- us2k10--------
    rs1814984791,2
    --31403333(+) TCAGCC/TTCTCA 1 -- us2k10--------
    rs80590291,2
    C,F,--31403587(+) tggatG/Ttggtg 1 -- us2k11Minor allele frequency- T:0.12WA 118
    rs802796551,2
    C,--31403598(+) GCTCAC/TGCCTG 1 -- us2k12Minor allele frequency- T:0.03WA 120
    rs1409701551,2
    --31403674(+) TGGGCA/GACATA 1 -- us2k10--------
    rs1501978571,2
    --31403681(+) CATAGA/TGCGAT 1 -- us2k10--------
    rs1387999841,2
    --31403771(+) GGGAGA/GATTGC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ITGAD (31404633 - 31437826 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ITGAD
         1 CNV: 66977

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ITGAD for disorders           About GeneDecksing

    OMIM gene information: 602453    OMIM disorders: --

    5 diseases for ITGAD:    About MalaCards
    monocytic leukemia    metastasis efficiency    chronic monocytic leukemia    leukemia
    obesity

    1 disease from the University of Copenhagen DISEASES database for ITGAD:
    Chronic monocytic leukemia

    Export disorders for ITGAD gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ITGAD gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with ITGAD)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit. (PubMed id 8666289)1, 2, 3 Wong D.A.... Springer T.A. (1996)
    2. Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb. (PubMed id 9598326)1, 3, 9 Shelley C.S....Arnaout M.A. (1998)
    3. Structural and functional characterization of the leukocyte integrin gene CD11d. Essential role of Sp1 and Sp3. (PubMed id 10722744)1, 2 Noti J.D.... Dillon J.D. (2000)
    4. The leukocyte integrin alpha D beta 2 binds VCAM-1: evidence for a binding interface between I domain and VCAM-1. (PubMed id 10438935)1, 2 Van der Vieren M.... Staunton D.E. (1999)
    5. Alphadbeta2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM- 1). (PubMed id 9841932)1, 2 Grayson M.H.... Bochner B.S. (1998)
    6. A novel leukointegrin, alpha d beta 2, binds preferentially to ICAM- 3. (PubMed id 8777714)1, 2 Van der Vieren M.... Gallatin W.M. (1995)
    7. Expression of the myeloid-specific leukocyte integrin gene CD11d during macrophage foam cell differentiation and exposure to lipoproteins. (PubMed id 12429998)1, 9 Noti J.D. (2002)
    8. On the potential involvement of CD11d in co-stimulati ng the production of interferon-I^ by natural killer cells upon interaction with neutrophils via intercellular adhesion molecule-3. (PubMed id 21712539)1 Costantini C....Cassatella M.A. (2011)
    9. Inflammatory phenotyping identifies CD11d as a gene m arkedly induced in white adipose tissue in obese rodents and women. (PubMed id 21508205)1 Thomas A.P....Adams S.H. (2011)
    10. The extracellular domain of CD11d regulates its cell surface expression. (PubMed id 19571252)1 McKillop W.M....Dekaban G.A. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3681 HGNC: 6146 AceView: ITGAD Ensembl:ENSG00000156886 euGenes: HUgn3681
    ECgene: ITGAD Kegg: 3681 H-InvDB: ITGAD

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ITGAD Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ITGAD Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ITGAD gene:
    Search GeneIP for patents involving ITGAD

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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