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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GYG2 Gene

protein-coding   GIFtS: 61
GCID: GC0XP002740

glycogenin 2
 Explore 4 diseases affiliated with
GYG2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for GYG2    

Aliases
for GYG2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Glycogenin 21 2
GN-21 2 3
GN22 3 5
EC 2.4.1.1863 8
Glycogenin Glucosyltransferase2
Glycogenin-21

External Ids:    HGNC: 47001   Entrez Gene: 89082   Ensembl: ENSG000000569987   OMIM: 3001985   UniProtKB: O154883   

Export aliases for GYG2 gene to outside databases

Previous GC identifers: GC0XP002051 GC0XP001915 GC0XP002276 GC0XP002341 GC0XP000690


Summaries
for GYG2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for GYG2:
This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the
initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked
gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a
short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively
spliced transcript variants encoding different isoforms have been identified.(provided by RefSeq, May 2010)

UniProtKB/Swiss-Prot: GLYG2_HUMAN, O15488
Function: Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate
for glycogen synthase




Genomic Views
for GYG2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_167197.1  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for GYG2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: GYG2 promoter sequence
   Search SABiosciences Chromatin IP Primers for GYG2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GYG2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.3   Ensembl cytogenetic band:  Xp22.33   HGNC cytogenetic band: Xp22.3

GYG2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GYG2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP002740:  view genomic region     (about GC identifiers)

Start:
 2,746,829 bp from pter      End:
 2,800,861 bp from pter
Size:
 54,033 bases      Orientation:
 plus strand

Proteins
for GYG2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: GLYG2_HUMAN, O15488 (See protein sequence)
Recommended Name: Glycogenin-2  
Size: 501 amino acids; 55184 Da
Cofactor: Divalent metal ions. Required for self-glucosylation. Manganese is the most effective
Subunit: Homodimer, tightly complexed to glycogen synthase
Mass spectrometry: Mass=55211.89; Method=MALDI; Range=1-501; Source=PubMed:11840567;
Secondary accessions: B7WNN6 O15485 O15486 O15487 O15489 O15490
Alternative splicing: 6 isoforms:  O15488-1   O15488-2   O15488-3   O15488-4   O15488-5   O15488-6   

Explore the universe of human proteins at neXtProt for GYG2: NX_O15488

Post-translational modifications:

  • Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around
    • 10 residues attached to Tyr-2281
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O15488

    • 4 DME Specific Peptides for GYG2 (O15488)
     TLTKLHCW  TDQAFVTL  AKVVHFLG  SAAPDPGWPDCFNSGVFV 

    GYG2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001073324.1  NP_001171631.1  NP_001171632.1  NP_001171633.1  NP_003909.2  

    ENSEMBL proteins: 
     ENSP00000381786   ENSP00000370555   ENSP00000430764   ENSP00000430752   ENSP00000370549  
     ENSP00000341273   ENSP00000446092  
    Reactome Protein details: O15488
    Human Recombinant Protein Products: 
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    OriGene Purified Protein: GYG2
    OriGene Protein Over-expression Lysate (see all 2): GYG2
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    Novus Biologicals GYG2 Proteins
    Novus Biologicals GYG2 Lysates
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    Uscn Proteins for GYG2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005625soluble fraction ----
    GO:0005829cytosol TAS--


    GYG2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for GYG2

    Protein Domains /
    Families
    for GYG2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    GYG2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR002495 Glyco_trans_8

    Graphical View of Domain Structure for InterPro Entry O15488

    ProtoNet protein and cluster: O15488

    1 Blocks protein family: IPB002495 Glycosyl transferase

    UniProtKB/Swiss-Prot: GLYG2_HUMAN, O15488
    Similarity: Belongs to the glycosyltransferase 8 family. Glycogenin subfamily


    Function
    for GYG2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: GLYG2_HUMAN, O15488
    Function: Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate
    for glycogen synthase
    Catalytic activity: UDP-alpha-D-glucose + glycogenin = UDP + alpha-D-glucosylglycogenin

         Genatlas biochemistry entry for GYG2:
    glycogenin self glycosylating protein 2,interacting with GYG,involved in initiation phase of glycogen
    biosynthesis,preferentially expressed in liver,heart and pancreas with several tissue specific,alternatively spliced
    isoforms

    Enzyme Number (IUBMB): EC 2.4.1.1861 2

    miRNA
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    hsa-miR-98 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-let-7i hsa-miR-196a hsa-let-7e hsa-let-7g
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    Inhib. RNA
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    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for GYG2

    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008466glycogenin glucosyltransferase activity IEA--
    GO:0016757transferase activity, transferring glycosyl groups ----


    GYG2 for ontologies           About GeneDecksing



    Pathways & Interactions
    for GYG2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Glycogen breakdown (glycogenolysis)
    		Glycogen breakdown (glycogenolysis)1.00
    		Glycogen Metabolism0.35
    2glycogen biosynthesis II (from UDP-D-Glucose)
    		glycogen biosynthesis II (from UDP-D-Glucose)1.00
    		Glycogen synthesis0.75
    3Glucose metabolism
    		Glucose metabolism1.00
    4Metabolism
    		Metabolism1.00
    5MPS IIIC - Sanfilippo syndrome C
    		Metabolism of carbohydrates0.47

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2 BioSystems Pathways for GYG2 
        Glycogen Metabolism
    glycogen biosynthesis II (from UDP-D-Glucose)

    5        Reactome Pathways for GYG2
        Metabolism of carbohydrates
    Glycogen breakdown (glycogenolysis)
    Metabolism
    Glucose metabolism
    Glycogen synthesis


    UniProtKB/Swiss-Prot: GLYG2_HUMAN, O15488
    Pathway: Glycan biosynthesis; glycogen biosynthesis


    GYG2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GYG2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/6 Interacting proteins for GYG2 (O154882, 3 ENSP000003705554) via UniProtKB, MINT, STRING, and/or I2D (see all 6)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    GYS1P138073, ENSP000003179044I2D: score=3 STRING: ENSP00000317904
    GYG1P469763, ENSP000003407364I2D: score=2 STRING: ENSP00000340736
    IKBKGQ9Y6K93, ENSP000003586224I2D: score=1 STRING: ENSP00000358622
    GYS2ENSP000002611954STRING: ENSP00000261195
    --Q9BTT93, 2MINT-68419 I2D: score=2 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0005978glycogen biosynthetic process TAS--
    GO:0005980glycogen catabolic process TAS--
    GO:0006006glucose metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--


    GYG2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for GYG2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for GYG2

    4 HMDB Compounds for GYG2    About this table
    CompoundSynonyms CAS #PubMed Ids
    GlycogenAnimal starch (see all 5)9005-79-2--
    Manganesemanganese 7439-96-5--
    Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
    Uridine diphosphate glucose(UPD)-glucose (see all 24)133-89-1--
    Search CenterWatch for drugs/clinical trials and news about GYG2 / GLYG2 

    Transcripts
    for GYG2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for GYG2 gene (5 alternative transcripts): 
    NM_001079855.1  NM_001184702.1  NM_001184703.1  NM_001184704.1  NM_003918.2  

    Unigene Cluster for GYG2:

    Glycogenin 2
    Hs.567381  [show with all ESTs]
    Unigene Representative Sequence: NM_003918
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000398806 ENST00000381163(uc004cqs.1 uc004cqu.1 uc004cqx.2 uc004cqt.1 uc004cqv.1 uc004cqw.1 uc010ndc.1)
    ENST00000381161 ENST00000522988 ENST00000520904 ENST00000469234 ENST00000353656
    ENST00000453106 ENST00000381157 ENST00000338623 ENST00000542787

    miRNA
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    hsa-miR-98 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-let-7i hsa-miR-196a hsa-let-7e hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmid: GYG2 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AK098046.1 AK292496.1 BC023152.1 DQ424901.1 U94357.1 U94358.1 U94360.1 U94361.1 
    U94362.1 U94363.1 

    9 DOTS entries:

    DT.91755536  DT.87003736  DT.91755531  DT.87016555  DT.121322734  DT.121322735  DT.102824391  DT.100026695 
    DT.100826532 

    24/104 AceView cDNA sequences (see all 104):

    CB410312 U94358 BQ645138 BQ676160 BU557030 CD657644 BU553391 BU553781 
    CD515269 U94363 AL703271 BP381934 BM825409 Z45205 AI142522 U94362 
    BM702362 BU729141 BG762340 AL698632 BQ694120 BM770578 BQ677592 BM992171 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for GYG2 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c · 14d
    SP1:              -                                                                                                     -                           
    SP2:                                -                                                                                   -                           
    SP3:                                                                                                                                                
    SP4:              -                 -                                                                                                               
    SP5:                                                                                                              -     -                           


    ECgene alternative splicing isoforms for GYG2

    Expression
    for GYG2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GYG2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCACGGGCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    GYG2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)Heart, Myocardium, Smooth Muscle
    PureStem™ progenitor EN2 (Embryonic Progenitor Cell)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See GYG2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GYG2

    SOURCE GeneReport for Unigene cluster: Hs.567381

    UniProtKB/Swiss-Prot: GLYG2_HUMAN, O15488
    Tissue specificity: Expressed preferentially in liver, heart, and pancreas

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    In Situ
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    Orthologs
    for GYG2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for GYG2 gene from 7/23 species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves GYG21 glycogenin 2 61.23(n)
    61.07(a)    		   418660  XM_416857.3  XP_416857.3 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 66(a)
    		 1 ↔ 1
    		 3(113924261-113935723)
    zebrafish
    (Danio rerio)    		 Actinopterygii gyg26
    		 glycogenin 2
    		 44(a)
    		 1 ↔ 1
    		 1(33002715-33019030)
    fruit fly
    (Drosophila melanogaster)    		 Insecta Glycogenin6
    		 Glycogenin
    		 23(a)
    		 1 → many
    		 2R(17087988-17100474)
    worm
    (Caenorhabditis elegans)    		 Secernentea T25E12.53
    gyg-21    		 glycogenin3
    Protein GYG-21    		 50(a)
    (best of 3)3
    52.97(n)1
    50.85(a)1    		   V(16747829-16748840)3
    1801191  NM_074837.31  NP_507238.11 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AtGolS46
    AtGolS36
    (see all 16)    		 galactinol synthase 3
    (see all 16)    		 25(a)
    22(a)
    (see all 16)    		 possible ortholog
    possible ortholog
    (see all 16)    		 1(22278975-22280586)
    1(3019819-3021441)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 10)    		 glycosyl transferase 8 domain containing protein, ...
    glycosyl transferase 8 domain containing protein, ...
    (see all 10)    		 22(a)
    22(a)
    (see all 10)    		 possible ortholog
    possible ortholog
    (see all 10)    		 7(29219291-29220851)
    3(11365917-11367637)


    ENSEMBL Gene Tree for GYG2 (if available)
    TreeFam Gene Tree for GYG2 (if available) 

    Paralogs
    for GYG2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GYG2 gene
    GYG2P12  GYG12  
    2 SIMAP similar genes for GYG2 using alignment to 4 protein entries:     GLYG2_HUMAN (see all proteins):
    GYG2P1    GYG1

    GYG2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for GYG2
    PGOHUM00000256886


    Genomic Variants
    for GYG2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1105 NCBI SNPs in GYG2 are shown (see all 1105)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr X posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1928807361,2
    		--2745034(+) TGCTGC/TCTCTT 5 -- us2k10--------
    rs1472186661,2
    		C,--2745052(+) GACACA/GTGAAG 5 -- us2k10--------
    rs1405643341,2
    		--2745094(+) TCATGC/TACTCA 5 -- us2k10--------
    rs625822841,2
    		C,--2745111(+) CATGCC/ACTCAC 5 -- us2k13Minor allele frequency- A:0.00NA 4
    rs625822851,2
    		C,--2745119(+) CACACA/CATCAT 5 -- us2k11Minor allele frequency- C:0.00NA 2
    rs625822861,2
    		C,--2745120(+) ACACCG/ATCATC 5 -- us2k11Minor allele frequency- A:0.00NA 2
    rs1893704191,2
    		--2745475(+) CATTCA/TCTCAT 5 -- us2k10--------
    rs1500039891,2
    		--2745607(+) CATTCA/GGCCAC 5 -- us2k10--------
    rs1924191811,2
    		--2745781(+) TGTACA/GAATTC 5 -- us2k10--------
    rs23162891,2
    		C,--2745951(-) ACAAGC/TGAATT 5 -- us2k1 tfbs31Minor allele frequency- T:0.00NA 2

    HapMap Linkage Disequilibrium report for GYG2 (2746829 - 2800861 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 11 variations for GYG2
         10 CNVs: 83277 3260 34412 8293 4142 7776 96405 8291 96406 52978
         1 Indel: 83278
    Locus Specific Mutation Databases (LSDB): GYG2

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    Disorders / Diseases
    for GYG2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    GYG2 for disorders           About GeneDecksing

    OMIM gene information: 300198    OMIM disorders: --

    4 diseases for GYG2:    About MalaCards
    glycogen storage disease type 0    glycogen storage disease    hypoglycemia    breast cancer

    Human Genome Epidemiology (HuGE) Navigator: GYG2 (1 document)

    Export disorders for GYG2 gene to outside databases

    Publications
    for GYG2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GYG2 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with GYG2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of human glycogenin-2, a self-glucosylating initiator of liver glycogen metabolism. (PubMed id 9857012)1, 2, 3, 9 Mu J. and Roach P.J. (1998)
    2. Structure and chromosomal localization of the human glycogenin-2 gene GYG2. (PubMed id 10721716)1, 2, 9 Zhai L.... Roach P.J. (2000)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Cluster analysis of an extensive human breast cancer cell line protein expression map database. (PubMed id 11840567)1, 2 Harris R.A....Zvelebil M.J. (2002)
    5. Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis. (PubMed id 9346895)1, 2 Mu J.... Roach P.J. (1997)
    6. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. (PubMed id 21248752)2 Varela I....Futreal P.A. (2011)
    7. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    8. Expanding the substantial interactome of NEMO using p rotein microarrays. (PubMed id 20098747)1 Fenner B.J....Prehn J.H. (2010)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    10. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)

    External Searches for GYG2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing GYG2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8908 HGNC: 4700 AceView: GYG2 Ensembl:ENSG00000056998 euGenes: HUgn8908
    ECgene: GYG2 H-InvDB: GYG2

    Other Databases showing GYG2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing GYG2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GYG2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for GYG2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for GYG2 gene:
    Search GeneIP for patents involving GYG2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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