GLRA3 Gene
protein-coding GIFtS: 61
GCID: GC04M175558
|
|
glycine receptor, alpha 3
| |
Aliases
for GLRA3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Glycine Receptor, Alpha 31 2 | | Glycine Receptor Alpha 3 Subunit2 | | Glycine Receptor Subunit Alpha-32 | | Glycine Receptor, Alpha-3 Polypeptide2 | | Ligand Gated Ion Channel2 |
Export aliases for GLRA3 gene to outside databasesPrevious GC identifers: GC04M176484 GC04M176102 GC04M176259 GC04M175938 GC04M175800 GC04M171312 |
Summaries
for GLRA3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for GLRA3:
The GLRA3 gene encodes the alpha-3 subunit of the neuronal glycine receptor, a ligand-gated chloride channel composedof ligand-binding alpha and structural beta polypeptides (Kingsmore et al., 1994 (PubMed 7894176)).(supplied by OMIM,Nov 2009)
UniProtKB/Swiss-Prot: GLRA3_HUMAN, O75311Function: The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increasesthe chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing)
 summary
for GLRA3: Glycine receptors (GlyR) are members of the cys-loop family of ligand-gated ion channels, responsible for
mediating the inhibitory effects of glycine. They are widely distributed throughout the CNS, particularly
within the hippocampus, spinal cord and brain stem. Glycine receptors exist as pentameric proteins,
homo-oligomers of the alpha isoforms (alpha1, alpha2, alpha3 or alpha4) or hetero-oligomers which also
contain the beta-subtype variant (beta1) which is essential for targeting the receptor to the synapse.
Glycine receptors contain an integral chloride channel, and have modulatory sites for anesthetics,
neurosteroids, cannabinoids and ethanol. Disruption in glycine receptor expression or ion channel function
can result in hyperekplexia, a rare neurological disorder.
Gene Wiki entry for GLRA3
|
Genomic Views
for GLRA3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the GLRA3 gene promoter:
POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 CBF-C C/EBPalpha HEN1 Egr-2 POU2F1 POU2F1a ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for GLRA3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLRA3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q34.1 Ensembl cytogenetic band: 4q34.1 HGNC cytogenetic band: 4q34.1GLRA3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M175558: view genomic region
(about GC identifiers)
Start:
|
175,558,065 bp from pter |
End:
|
175,750,465 bp from pter |
Size:
|
192,401 bases |
Orientation:
|
minus strand |
|
Proteins
for GLRA3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: GLRA3_HUMAN, O75311 (See
protein sequence)Recommended Name: Glycine receptor subunit alpha-3 precursor Size: 464 amino acids; 53800 Da
Subunit: Pentamer composed of alpha and beta subunits (By similarity)
Subcellular location: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane;Multi-pass membrane protein
Miscellaneous: The alpha subunit binds strychnine
Secondary accessions: D3DP44 O75816 Q5D0E3Alternative splicing: 2 isoforms: O75311-1 O75311-2 Explore the universe of human proteins at neXtProt for GLRA3: NX_O75311
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75311
GLRA3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001036008.1 NP_006520.2
ENSEMBL proteins: ENSP00000274093 ENSP00000345284 Reactome Protein details: O75311
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
GLRA3 for ontologies About GeneDecksing
GLRA3 Antibody Products:
Assay Products for GLRA3: |
Protein
Domains /
Families
for GLRA3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GLRA3 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry O75311ProtoNet protein and cluster: O75311 3 Blocks protein families: IPB006028 Gamma-aminobutyric acid A (GABAA) receptor signature IPB006201 Neurotransmitter-gated ion-channel IPB008130 Glycine receptor alpha 3 subunit signature
UniProtKB/Swiss-Prot: GLRA3_HUMAN, O75311Domain: The N-terminal domain carries structural determinants essential for agonist and antagonist binding. TM2 isthought to form the innert wall of the chloride channel. The cytoplasmic loop is an important determinant of channelinactivation kineticsSimilarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA3sub-subfamily |
Function
for GLRA3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: GLRA3_HUMAN, O75311Function: The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increasesthe chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) Genatlas biochemistry entry for GLRA3:glycine receptor,alpha 3 subunit expressed in the central nervous system,with two splice variants GLRA3L,GLRA3K
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLRA3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for GLRA3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLRA3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRA3 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004872 | receptor activity |
-- | -- | | GO:0005230 | extracellular ligand-gated ion channel activity |
NAS | -- | | GO:0016594 | glycine binding |
IEA | -- | | GO:0016934 | extracellular-glycine-gated chloride channel activity |
IEA | -- | | GO:0022824 | transmitter-gated ion channel activity |
IEA | -- |
GLRA3 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Glra3tm1.1Umu for GLRA3
5 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Glra3):
GLRA3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for GLRA3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | PKA activation in glucagon signalling | | | 2 | Ion channel transport | | | 3 | SLC-mediated transmembrane transport | | | 4 | GABA A receptor activation | | | 5 | Class A/1 (Rhodopsin-like receptors) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for GLRA3
1  GeneGo (Thomson Reuters) Pathway for GLRA3
3 
Reactome Pathways for GLRA3
1 
Kegg Pathway (Kegg details for GLRA3):
GLRA3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GLRA3
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5 Interacting proteins for GLRA3 (O753113 ENSP000002740934) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007268 | synaptic transmission |
NAS | -- | | GO:0034220 | ion transmembrane transport |
TAS | -- | | GO:0055085 | transmembrane transport |
TAS | -- |
GLRA3 for ontologies About GeneDecksing
|
Drugs & Compounds
for GLRA3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for GLRA3 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| beta-Alanine | Endogenous glycine agonist, more selective than taurine (Cat. No. 0209) | [107-95-9] | | Strychnine hydrochloride | Competitive glycine receptor antagonist | [1421-86-9] | | L-Serine | Weak endogenous glycine receptor agonist | [56-45-1] | | Hypotaurine | Non-selective endogenous glycine receptor agonist | [300-84-5] | | Glycine | Endogenous potentiator, co-transmitter | [56-40-6] |
2 HMDB Compounds for GLRA3 About this table
4 DrugBank Compounds for GLRA3 About this table
Search CenterWatch for drugs/clinical trials and news about GLRA3
|
Transcripts
for GLRA3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for GLRA3 gene (2 alternative transcripts): NM_001042543.1 NM_006529.2 Unigene Cluster for GLRA3: Glycine receptor, alpha 3 Hs.413099 [show with all ESTs]Unigene Representative Sequence: NM_0065294 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000274093(uc003ity.1 uc003itz.1) ENST00000340217 ENST00000483010
ENST00000436738
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLRA3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLRA3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): GLRA3 (NM_001042543) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GLRA3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLRA3 |
Additional cDNA sequence: AF018157.1 BC036086.1 U93917.1 4 DOTS entries: DT.91699388 DT.100745272 DT.91699381 DT.99962581 22 AceView cDNA sequences: AA283884 AA283885 AW298713 AW297385 AI761703 U93917 BX091928 BC036086 NM_006529 AA489056 BI825190 BG193387 AA872485 BG203115 AF018157 AA488804 BI600831 BG189196 BG196871 BE830621 BE830616 BG186165
GeneLoc Exon Structure
|
Expression
for GLRA3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GLRA3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See GLRA3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GLRA3
SOURCE GeneReport for Unigene cluster: Hs.413099
UniProtKB/Swiss-Prot: GLRA3_HUMAN, O75311Tissue specificity: Widely distributed throughout the central nervous system
SABiosciences Custom PCR Arrays for GLRA3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GLRA3
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRA3 |
Orthologs
for GLRA3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for GLRA3 gene from 5/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
GLRA31 |
glycine receptor, alpha 3 |
81.51(n)
92.62(a) |
|
422568 XM_420527.1 XP_420527.1 |
lizard
(Anolis carolinensis) |
Reptilia |
GLRA36 |
-- |
90(a) |
1 ↔ 1 |
3(143720534-143802968) |
zebrafish
(Danio rerio) |
Actinopterygii |
glra31 |
glycine receptor, alpha 3 |
74.19(n)
88.14(a) |
|
192124 NM_152965.1 NP_694497.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Grd3 |
glycine-gated ion channel |
47(a)
(best of 7) |
|
75A4 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
avr-143
glc-21 |
Expression: neurons, nerve ring, ventral
cord more3
Protein GLC-21 |
38(a)
(best of 22)3
50.13(n)1
42.49(a)1 |
|
I(5975551-5981456)3
1721031 NM_059069.31 NP_491470.11 |
ENSEMBL Gene Tree for GLRA3 (if available)
TreeFam Gene Tree for GLRA3 (if available) |
Paralogs
for GLRA3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for GLRA3 gene
- GLRA22 GABRR12 GLRB2 GLRA12 GABRB12 GABRD2 GLRA42 GABRP2
- GABRB22 GABRQ2 GABRB32 GABRR22
18/25 SIMAP similar genes for GLRA3 using alignment to 3 protein entries: GLRA3_HUMAN (see all proteins)
(see all similar genes):GLRA1 GLRA2 GLRA4 GABRP GABRG3 GABRQ
GABRA6 GABRE GABRR3 GABRR2 GLRB GABRA5
GABRR1 GABRA2 GABRD GABRB3 GABRA3 GABRA4
GLRA3 for paralogs About GeneDecksing
|
Genomic Variants
for GLRA3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for GLRA3
4 CNVs: 39406 92552 64035 62290
2 Indels: 46559 80585 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GLRA3 |
|
Disorders
/ Diseases
for GLRA3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GLRA3 for disorders About GeneDecksing
OMIM gene information: 600421
OMIM disorders: --
5  diseases for GLRA3: About MalaCardshyperekplexia idiopathic generalized epilepsy generalized epilepsy neuronitis
pharyngitis
Genetic Association Database (GAD): GLRA3
Human Genome Epidemiology (HuGE) Navigator: GLRA3 (2 documents)
Export disorders for GLRA3 gene to outside databases
|
Publications
for GLRA3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GLRA3 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with GLRA3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human glycine receptor subunit alpha3. GLRA3 gene structure, chromosomal localization, and functional characterization of alternative transcripts. (PubMed id 9677400)1, 2, 3, 9 Nikolic Z.... Becker C.-M. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Genetic variation of the human glycine receptor subun it genes GLRA3 and GLRB and susceptibility to idiopathic generalized epilepsies . (PubMed id 11496371)1, 4 Sobetzko D....Becker C.M. (2001)
- Novel regulatory site within the TM3-4 loop of human recombinant alpha3 glycine receptors determines channel gating and domain struc ture. (PubMed id 19661067)1, 9 Breitinger H.G....Becker C.M. (2009)
- Hydroxylated residues influence desensitization behaviour of recombinant alpha3 glycine receptor channels. (PubMed id 12358726)1, 9 Breitinger H.G....Becker C.M. (2002)
- Dual actions of lindane (I^-hexachlorocyclohexane) on calcium homeostasis and exocytosis in rat PC12 cells. (PubMed id 20600211)7 Heusinkveld H.J....Westerink R.H. (2010)
- Multifunctional basic motif in the glycine receptor i ntracellular domain induces subunit-specific sorting. (PubMed id 19959465)1 Melzer N....Becker C.M. (2010)
- An ivermectin-sensitive glutamate-gated chloride chan nel from the parasitic nematode Haemonchus contortus. (PubMed id 19336526)7 McCavera S....Wolstenholme A.J. (2009)
- Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1 GratacA^s M....Carracedo A. (2008)
- A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. (PubMed id 17714449)7 Yang Z....Lynch J.W. (2007)
|
External Searches for GLRA3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing GLRA3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GLRA3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GLRA3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for GLRA3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for GLRA3 gene:
Search GeneIP for patents involving GLRA3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for GLRA3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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variant library, vector shuttling | | | OriGene Custom Antibody Services for GLRA3 | | OriGene Custom Protein Services for GLRA3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GLRA3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GLRA3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLRA3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GLRA3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLRA3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLRA3 |
| |
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| | | | Tocris compounds for GLRA3 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRA3 |
|  |  |  | | | | Search ThermoFisher Antibodies for GLRA3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLRA3 |
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