FAM104A Gene
protein-coding GIFtS: 38
GCID: GC17M071203
|
|
family with sequence similarity 104, member A
| |
Aliases
for FAM104A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 104, Member A1 2 | | FLJ147751 | | Protein FAM104A2 |
Export aliases for FAM104A gene to outside databasesPrevious GC identifers: GC17M068716 GC17M066612 |
Summaries
for FAM104A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM104A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM104A gene promoter:
STAT1 AML1a MEF-2 MyoD Nkx2-5 STAT1alpha C/EBPalpha MEF-2A aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM104A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM104A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.1FAM104A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M071203: view genomic region
(about GC identifiers)
Start:
|
71,203,492 bp from pter |
End:
|
71,232,892 bp from pter |
Size:
|
29,401 bases |
Orientation:
|
minus strand |
|
Proteins
for FAM104A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F104A_HUMAN, Q969W3 (See
protein sequence)Recommended Name: Protein FAM104A Size: 186 amino acids; 19484 Da
Sequence caution: Sequence=AAH11054.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAH25238.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB55292.1;Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAC11183.1; Type=Erroneous initiation;Note=Translation N-terminally extended;
Secondary accessions: B4E339Alternative splicing: 2 isoforms: Q969W3-1 Q969W3-2 Explore the universe of human proteins at neXtProt for FAM104A: NX_Q969W3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q969W3
FAM104A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001092302.1 NP_116226.2
ENSEMBL proteins: ENSP00000384648 ENSP00000384832 ENSP00000462781 ENSP00000462840 ENSP00000462806 ENSP00000462507
Human Recombinant Protein Products:
FAM104A Antibody Products:
Assay Products for FAM104A: |
Protein
Domains /
Families
for FAM104A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q969W3 UniProtKB/Swiss-Prot: F104A_HUMAN, Q969W3Similarity: Belongs to the FAM104 family |
Function
for FAM104A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM104A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM104A (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): FAM104A (NM_032837) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM104A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM104A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM104A |
1 GenomeRNAi human phenotype for FAM104A:
Animal Models:
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Fam104a):
FAM104A for phenotypes About GeneDecksing
|
Pathways & Interactions
for FAM104A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM104A
|
Drugs & Compounds
for FAM104A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM104A
Search CenterWatch for drugs/clinical trials and news about FAM104A / F104A
|
Transcripts
for FAM104A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM104A gene (2 alternative transcripts): NM_001098832.1 NM_032837.2 Unigene Cluster for FAM104A: Family with sequence similarity 104, member A Hs.741276 [show with all ESTs]Unigene Representative Sequence: NM_0010988327 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000403627 ENST00000405159(uc002jjj.4 uc002jji.4) ENST00000583178
ENST00000580032 ENST00000581110 ENST00000579872 ENST00000583024
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM104A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM104A (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): FAM104A (NM_032837) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM104A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM104A |
Additional cDNA sequence: AK027681.1 AK074755.1 AK304556.1 BC011054.1 BC025238.1 BX537858.1 BX648968.1 U92989.1 20 DOTS entries: DT.99989533 DT.100824747 DT.91766570 DT.100824753 DT.120979144 DT.120979154 DT.100029669 DT.99978632 DT.120979174 DT.100029671 DT.95156930 DT.97800558 DT.120979072 DT.120979095 DT.120979099 DT.95156949 DT.95269183 DT.100655618 DT.86851235 DT.95156940 24/232 AceView cDNA sequences (see all 232): AI768146 BM930907 CB154919 BM807916 BQ008898 AI910446 R29378 BM976293 BC025238 AI147224 BP342451 AA933586 CD364915 BE042985 AK027681 BM980270 CA429207 NM_032837 AI634908 AA482533 AA993417 BM423910 AW025742 AI638199
GeneLoc Exon Structure
|
Expression
for FAM104A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM104A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACACAGCAC
About this image
See FAM104A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM104A
SOURCE GeneReport for Unigene cluster: Hs.741276
SABiosciences Custom PCR Arrays for FAM104A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM104A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM104A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM104A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM104A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM104A |
Orthologs
for FAM104A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM104A gene from 2/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
FAM104A1 |
family with sequence similarity 104, member A |
72.22(n)
70.63(a) |
|
417450 NM_001030708.1 NP_001025879.1 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
66(a) |
1 → many |
2(96806177-96812074) |
ENSEMBL Gene Tree for FAM104A (if available)
TreeFam Gene Tree for FAM104A (if available) |
Paralogs
for FAM104A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM104A gene
- FAM104B2
1 SIMAP similar gene for FAM104A using alignment to 5 protein entries: F104A_HUMAN (see all proteins):FAM104B
FAM104A for paralogs About GeneDecksing
|
Genomic Variants
for FAM104A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM104A (71203492 - 71232892 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for FAM104A
2 CNVs: 43954 102529 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM104A |
|
Disorders
/ Diseases
for FAM104A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM104A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM104A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM104A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Mapping and characterization of novel (CAG)n repeat cDNAs from adult human brain derived by the oligo capture method. (PubMed id 9417904)1, 2 Reddy P.H....Tagle D.A. (1997)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for FAM104A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM104A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM104A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM104A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM104A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM104A gene:
Search GeneIP for patents involving FAM104A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM104A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM104A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM104A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM104A | | | OriGene Protein Over-expression Lysate for FAM104A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM104A | | OriGene 3'-UTR Clone for FAM104A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM104A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM104A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM104A | | OriGene Custom Protein Services for FAM104A | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM104A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM104A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM104A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM104A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM104A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM104A |
| |
 |  |  |  | |
| | | | Search Tocris compounds for FAM104A |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | FAM104A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM104A |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM104A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM104A |
|
|
|
|
