DEGS1 Gene
protein-coding GIFtS: 53
GCID: GC01P224364
|
|
delta(4)-desaturase, sphingolipid 1(Previous names: degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)...)
| |
Aliases
for DEGS1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Delta(4)-Desaturase, Sphingolipid 11 2 | | Degenerative Spermatocyte Homolog 1, Lipid Desaturase2 | | DES11 2 3 | | Degenerative Spermatocyte Homolog, Lipid Desaturase2 | | MLD1 2 3 | | Dihydroceramide Desaturase2 | | DEGS-11 2 | | Membrane Fatty Acid (Lipid) Desaturase2 | | Des-11 2 | | Migration-Inducing Gene 15 Protein2 | | FADS71 2 | | Sphingolipid Delta 4 Desaturase2 | | Cell Migration-Inducing Gene 15 Protein2 3 | | Sphingolipid Delta(4)-Desaturase 12 | | Membrane Lipid Desaturase2 3 | | Sphingolipid Delta(4)-Desaturase DES12 | | Degenerative Spermatocyte Homolog 1, Lipid Desaturase (Drosophila)1 | | EC 1.14.-.-3 | | DEGS2 | | Degenerative Spermatocyte Homolog 13 |
Export aliases for DEGS1 gene to outside databasesPrevious GC identifers: GC01P220678 GC01P222437 GC01P194891 |
Summaries
for DEGS1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DEGS1:
This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bondsinto specific positions in fatty acids. This protein contains three His-containing consensus motifs that arecharacteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanningprotein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGFreceptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGFreceptor. (provided by RefSeq, Mar 2010)
UniProtKB/Swiss-Prot: DEGS1_HUMAN, O15121Function: Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine(E-sphing-4-enine)
|
Genomic Views
for DEGS1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DEGS1 gene promoter:
Max1 ATF-2 FOXO3 AP-2gamma RORalpha2 FOXO3b AP-2beta FOXO3a ZIC2/Zic2 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for DEGS1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DEGS1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q42.11 Ensembl cytogenetic band: 1q42.11 HGNC cytogenetic band: 1q41-q42.12DEGS1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P224364: view genomic region
(about GC identifiers)
Start:
|
224,363,458 bp from pter |
End:
|
224,381,143 bp from pter |
Size:
|
17,686 bases |
Orientation:
|
plus strand |
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Proteins
for DEGS1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DEGS1_HUMAN, O15121 (See
protein sequence)Recommended Name: Sphingolipid delta(4)-desaturase DES1 Size: 323 amino acids; 37866 Da
Subcellular location: Mitochondrion. Endoplasmic reticulum membrane; Multi-pass membrane proteinExplore the universe of human proteins at neXtProt for DEGS1: NX_O15121
Post-translational modifications:
Myristoylation can target the enzyme to the mitochondria leading to an increase in ceramide levels1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15121
DEGS1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003667.1
ENSEMBL proteins: ENSP00000400545 ENSP00000316476 ENSP00000375749 Reactome Protein details: O15121
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
DEGS1 for ontologies About GeneDecksing
DEGS1 Antibody Products:
Assay Products for DEGS1: |
Protein
Domains /
Families
for DEGS1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DEGS1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15121ProtoNet protein and cluster: O15121 UniProtKB/Swiss-Prot: DEGS1_HUMAN, O15121Similarity: Belongs to the fatty acid desaturase family. DEGS subfamily |
Function
for DEGS1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: DEGS1_HUMAN, O15121Function: Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine(E-sphing-4-enine)Enzyme Number (IUBMB): EC 1.14.-.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DEGS1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DEGS1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DEGS1 (NM_003676) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DEGS1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DEGS1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEGS1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0009055 | electron carrier activity |
TAS | 9188692 | | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
IEA | -- |
DEGS1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for DEGS1:
Animal Models:
1 MGI phenotypic allele  for Degs1 (no phenotypes)
DEGS1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for DEGS1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sphingolipid metabolism | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4 
Reactome Pathways for DEGS1
2 
Kegg Pathways (Kegg details for DEGS1):
DEGS1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DEGS1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/38 Interacting proteins for DEGS1 (O151211, 3 ENSP000003164764) via UniProtKB, MINT, STRING, and/or I2D (see all 38)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| PYGM | P112171, 3, ENSP000001641394 | EBI-1052713,EBI-357469 I2D:
score=2 STRING: ENSP00000164139 | | SURF4 | O152601, 3, ENSP000003610574 | EBI-1052713,EBI-1044848 I2D:
score=2 STRING: ENSP00000361057 | | TSSC1 | Q53HC91, 3, ENSP000003715594 | EBI-1052713,EBI-1055422 I2D:
score=2 STRING: ENSP00000371559 | | SLC16A1 | P539851, 3, ENSP000003586404 | EBI-1052713,EBI-1054708 I2D:
score=2 STRING: ENSP00000358640 | | MOB1A | Q9H8S93, ENSP000003793644 | I2D:
score=1 STRING: ENSP00000379364 |
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006633 | fatty acid biosynthetic process |
-- | -- | | GO:0006636 | unsaturated fatty acid biosynthetic process |
TAS | 9188692 | | GO:0006644 | phospholipid metabolic process |
TAS | -- | | GO:0006665 | sphingolipid metabolic process |
TAS | -- | | GO:0030148 | sphingolipid biosynthetic process |
TAS | -- |
DEGS1 for ontologies About GeneDecksing
|
Drugs & Compounds
for DEGS1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
DEGS1 for compounds About GeneDecksing
 Browse Tocris compounds for DEGS1
5 Novoseek chemical compound relationships for DEGS1 gene About this table
Search CenterWatch for drugs/clinical trials and news about DEGS1
|
Transcripts
for DEGS1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DEGS1 gene (2 alternative transcripts): NM_144780.1 NM_003676.3 Unigene Cluster for DEGS1: Delta(4)-desaturase, sphingolipid 1 Hs.299878 [show with all ESTs]Unigene Representative Sequence: NM_0036765 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000415210 ENST00000323699(uc001hoj.3) ENST00000465848 ENST00000498813
ENST00000391877
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DEGS1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DEGS1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DEGS1 (NM_003676) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DEGS1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DEGS1 |
Additional cDNA sequence: AF466375.1 AK308232.1 AY423730.1 BC000961.2 15 DOTS entries: DT.448126 DT.121643628 DT.92446266 DT.100742090 DT.100793488 DT.95273830 DT.100795095 DT.100793482 DT.121361227 DT.100793486 DT.86811136 DT.92039352 DT.99943904 DT.121361198 DT.121361217 24/229 AceView cDNA sequences (see all 229): AL547045 CR602386 BQ019992 AU280481 BQ889257 AU119618 AI536858 CR599325 BM466697 AA809857 BG286931 CB216544 BU735878 CA308765 CN485297 BC000961 CR623303 BU190956 BU625232 CA431515 BM849148 AA486501 BX343669 CR612716
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for DEGS1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
|---|
|
| SP1: | | | - | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | - | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for DEGS1
|
Expression
for DEGS1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DEGS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTTCCCCAA
About this image
See DEGS1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DEGS1
SOURCE GeneReport for Unigene cluster: Hs.299878
UniProtKB/Swiss-Prot: DEGS1_HUMAN, O15121Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for DEGS1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DEGS1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DEGS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DEGS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DEGS1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEGS1 |
Orthologs
for DEGS1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DEGS1 gene from 8/28 species (see all 28) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
DEGS11 |
degenerative spermatocyte homolog 1, lipid desaturase more |
75.73(n)
82.81(a) |
|
421327 NM_001012565.1 NP_001012583.1 |
lizard
(Anolis carolinensis) |
Reptilia |
DEGS16 |
-- |
74(a) |
1 ↔ 1 |
1(252782266-252790979) |
African clawed frog
(Xenopus laevis) |
Amphibia |
degs-prov2 |
degenerative spermatocyte homolog, lipid desaturase more |
75.73(n) |
|
BC054207.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufa25h012 |
Danio rerio cDNA clone MGC63989 IMAGE6792520, complete more |
76.07(n) |
|
BC053183.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
ifc6 |
infertile crescent |
61(a) |
1 → many |
2L(5986348-5988854) |
worm
(Caenorhabditis elegans) |
Secernentea |
F33D4.41 |
Protein F33D4.4 |
58.63(n)
50.81(a) |
|
177548 NM_068855.3 NP_501256.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
DES-1-LIKE6 |
sphingolipid delta-4 desaturase |
48(a) |
1 → many |
4(2509133-2511145) |
rice
(Oryza sativa) |
Liliopsida |
Os.234112 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
74.4(n) |
|
AK101968.1 |
ENSEMBL Gene Tree for DEGS1 (if available)
TreeFam Gene Tree for DEGS1 (if available) |
Paralogs
for DEGS1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DEGS1 gene
- DEGS22
2 SIMAP similar genes for DEGS1 using alignment to 2 protein entries: DEGS1_HUMAN (see all proteins):DEGS DEGS2
DEGS1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for DEGS1
PGOHUM00000249600
|
Genomic Variants
for DEGS1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DEGS1 (224363458 - 224381143 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for DEGS1
1 CNV: 30456 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DEGS1 |
|
Disorders
/ Diseases
for DEGS1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DEGS1 for disorders About GeneDecksing
5  diseases for DEGS1: About MalaCardsgastric cancer infertility hypoxia neuroblastoma
neuronitis
Export disorders for DEGS1 gene to outside databases
|
Publications
for DEGS1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DEGS1 gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with DEGS1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis. (PubMed id 9188692)1, 2, 3, 9 Cadena D.L.... Gill G.N. (1997)
- Dihydroceramide desaturase activity is modulated by o xidative stress. (PubMed id 20105137)1, 3, 9 Idkowiak-Baldys J....Hannun Y.A. (2010)
- Identification and characterization of a sphingolipid delta 4- desaturase family. (PubMed id 11937514)1, 2 Ternes P.... Heinz E. (2002)
- Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells. (PubMed id 17283068)1, 9 Kraveka J.M....Bielawska A. (2007)
- Cell density-dependent reduction of dihydroceramide de saturase activity in neuroblastoma cells. (PubMed id 22377532)1 Spassieva S.D....Obeid L.M. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
- Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression. (PubMed id 22628619)1 Ruangsiriluk W....Francone O.L. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for DEGS1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DEGS1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DEGS1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DEGS1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DEGS1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DEGS1 gene:
Search GeneIP for patents involving DEGS1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DEGS1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DEGS1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DEGS1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DEGS1 | | | OriGene Protein Over-expression Lysate for DEGS1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DEGS1 | | OriGene 3'-UTR Clone for DEGS1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DEGS1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DEGS1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DEGS1 | | OriGene Custom Protein Services for DEGS1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DEGS1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DEGS1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DEGS1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DEGS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DEGS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DEGS1 |
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| | | | Search Tocris compounds for DEGS1 |
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 | | | DEGS1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEGS1 |
|  |  |  | | | | ThermoFisher Antibodies for DEGS1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DEGS1 |
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