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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ATAD2 Gene

protein-coding GIFtS: 48
GCID: GC08M124332

ATPase family, AAA domain containing 2

Explore 15 diseases affiliated with
ATAD2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
ATPase Family, AAA Domain Containing 2¹ ²		MGC29843¹
ANCCA² ³ ⁵		MGC5254¹
PRO2000¹ ²		ATPase Family AAA Domain-Containing Protein 2²
AAA Nuclear Coregulator Cancer-Associated Protein² ³		EC 3.6.1.3³
DKFZp667N1320¹

External Ids:	HGNC: 30123¹	Entrez Gene: 29028²	Ensembl: ENSG00000156802⁷	OMIM: 611941⁵	UniProtKB: Q6PL18³

Export aliases for ATAD2 gene to outside databases

Previous GC identifers: GC08M124292 GC08M124401 GC08M119657

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ATAD2:

A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220

amino acids that contains an ATP-binding site. The proteins that belong to this family either contain one or two AAA

(ATPases Associated with diverse cellular Activities) domains. AAA family proteins often perform chaperone-like

functions that assist in the assembly, operation, or disassembly of protein complexes. The protein encoded by this

gene contains two AAA domains, as well as a bromodomain. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ATAD2_HUMAN, Q6PL18

Function: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a

subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of

CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the

estrogen-induced cell proliferation and cell cycle progression of breast cancer cells

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000008.10 NC_018919.1 NT_008046.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ATAD2 gene promoter:
AML1a p53 RREB-1 CREB HEN1 POU2F1 FOXO4 POU2F1a deltaCREB ZIC2/Zic2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ATAD2 promoter sequence

Search SABiosciences Chromatin IP Primers for ATAD2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATAD2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.13 Ensembl cytogenetic band: 8q24.13 HGNC cytogenetic band: 8q24.13

ATAD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATAD2 gene location

GeneLoc information about chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M124332: view genomic region (about GC identifiers)

Start:	124,332,090 bp from pter	End:	124,428,590 bp from pter
Size:	96,501 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ATAD2_HUMAN, Q6PL18 (See protein sequence)

Recommended Name: ATPase family AAA domain-containing protein 2

Size: 1390 amino acids; 158554 Da

Subunit: Interacts with ESR1 and NCOA3 and these interactions are enhanced by estradiol. Interacts with acetylated

lysine residues on histone H1.4, H2A, H2B and H3 (in vitro)

Subcellular location: Nucleus

Sequence caution: Sequence=AAF22032.1; Type=Erroneous initiation; Sequence=AAH10686.1; Type=Miscellaneous discrepancy;

Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part (676-679); Sequence=AAH19909.1;

Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for ATAD2:

3DAI (3D)

Secondary accessions: Q14CR1 Q658P2 Q68CQ0 Q6PJV6 Q8N890 Q9UHS5

Alternative splicing: 2 isoforms: Q6PL18-1 Q6PL18-2 (No experimental confirmation available. Dubious isoform. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for ATAD2: NX_Q6PL18

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6PL18

ATAD2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_054828.2

ENSEMBL proteins:

ENSP00000429331 ENSP00000287394 ENSP00000429213 ENSP00000429617

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	Uscn Proteins for ATAD2

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--

ATAD2 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ATAD2 for domains About GeneDecksing

5 InterPro domains/families:

IPR003959 ATPase_AAA_core

IPR003960 ATPase_AAA_CS

IPR011989 ARM-like

IPR001487 Bromodomain

IPR003593 AAA+_ATPase

Graphical View of Domain Structure for InterPro Entry Q6PL18

ProtoNet protein and cluster: Q6PL18

2 Blocks protein families:

IPB001487 Bromodomain signature

IPB003960 AAA-protein subdomain

UniProtKB/Swiss-Prot: ATAD2_HUMAN, Q6PL18

Similarity: Belongs to the AAA ATPase family

Similarity: Contains 1 bromo domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ATAD2_HUMAN, Q6PL18

Function: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a

subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of

CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the

estrogen-induced cell proliferation and cell cycle progression of breast cancer cells

Catalytic activity: ATP + H(2)O = ADP + phosphate

Induction: Up-regulated in breast, uterus, colon, ovary, and stomach tumors. Induced in breast cancer cells

overexpressing NCOA3 or treated with estrogen. Down-regulated in 5-fluorouracil-resistant derivatives of the colon

cancer cell line HCT 116

Enzyme Number (IUBMB): EC 3.6.1.3¹

miRNA Products:		OriGene 3'-UTR Clone: ATAD2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ATAD2
		8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate ATAD2 (see all 43):
		hsa-miR-548j hsa-miR-520e hsa-miR-302d hsa-miR-520f hsa-miR-106a hsa-miR-374a hsa-miR-374a* hsa-miR-374c

		SwitchGear 3'UTR luciferase reporter plasmid: ATAD2 3' UTR sequence

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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATAD2

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005524	ATP binding	IEA	--
GO:0016887	ATPase activity	IEA	--

ATAD2 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ATAD2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/147 Interacting proteins for ATAD2 (Q6PL18³ ENSP00000287394⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 147)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HIST2H4A	P62805³, ENSP00000358162⁴	I2D: score=5 STRING: ENSP00000358162
HIST1H4A	P62805³	I2D: score=5
HIST1H4B	P62805³	I2D: score=5
HIST1H4C	P62805³	I2D: score=5
HIST1H4D	P62805³	I2D: score=5

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--

ATAD2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ATAD2
Search CenterWatch for drugs/clinical trials and news about ATAD2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ATAD2 gene:

NM_014109.3

Unigene Cluster for ATAD2:

ATPase family, AAA domain containing 2

Hs.370834 [show with all ESTs]

Unigene Representative Sequence: NM_014109

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000517666 ENST00000287394(uc011lii.2 uc003yqh.4 uc003yqi.4)

ENST00000521903 ENST00000519124 ENST00000521496(uc003yqj.3) ENST00000550993

ENST00000534257 ENST00000530065

miRNA Products:		OriGene 3'-UTR Clone: ATAD2 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ATAD2
		8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate ATAD2 (see all 43):
		hsa-miR-548j hsa-miR-520e hsa-miR-302d hsa-miR-520f hsa-miR-106a hsa-miR-374a hsa-miR-374a* hsa-miR-374c

		SwitchGear 3'UTR luciferase reporter plasmid: ATAD2 3' UTR sequence

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Additional cDNA sequence:

AF118088.1 AK097133.1 AL833653.1 AY598335.1 BC010686.1 BC019909.1 BC112942.1 BC113656.1

BC143716.1 CR749832.1

12 DOTS entries:

DT.441446 DT.100777335 DT.91750028 DT.100777333 DT.121485529 DT.422400 DT.100655985 DT.121485560

DT.91734891 DT.91862825 DT.92022435 DT.95367627

24/170 AceView cDNA sequences (see all 170):

AI458836 BI861220 AK097133 BE672344 BU187148 AL833653 NM_014109 AA287933

AA897632 CB120155 AA429083 BQ896166 AW512901 BM559313 Z40387 BQ437555

AI133393 AA995158 AW151919 BX094206 AI240868 Z44462 BC007123 CD359169

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ATAD2 (see all 12) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11a	·	11b	^	12	^	13a	·	13b	^	14a	·	14b	^	15	^	16a	·	16b	·	16c	·	16d	^	17a	·
SP1:									-
SP2:
SP3:
SP4:
SP5:

ExUns:	17b	·	17c	^	18a	·	18b	^	19a	·	19b	^	20	^	21a	·	21b	·	21c	^	22a	·	22b	^	23	^	24a	·	24b	^	25
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for ATAD2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ATAD2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTTGCGGGA

About this image

ATAD2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

3 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Neural Tube

Diencephalic Ventricular Zone

Neural Tube

Mesencephalic Ventricular Zone

Neural Tube

Telencephalon

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ATAD2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATAD2

SOURCE GeneReport for Unigene cluster: Hs.370834

UniProtKB/Swiss-Prot: ATAD2_HUMAN, Q6PL18

Tissue specificity: Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors

SABiosciences Custom PCR Arrays for ATAD2

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ATAD2 gene from 8/27 species (see all 27) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ATAD2¹	ATPase family, AAA domain containing 2	67.26(n) 63.8(a)		420346 XM_418453.3 XP_418453.3
lizard (Anolis carolinensis)	Reptilia	ATAD2⁶	--	69(a)	1 ↔ 1	4(6800192-6828489)
African clawed frog (Xenopus laevis)	Amphibia	Xl.25675²	Xenopus laevis transcribed sequence with moderate similarity more	75.69(n)		BU901193.1
zebrafish (Danio rerio)	Actinopterygii	wu:fi16e04¹	wu:fi16e04	60.14(n) 60.09(a)		327543 XM_003200248.1 XP_003200296.1
honey bee (Apis mellifera)	Insecta	-- --	--	40(a) 32(a)	many ↔ many many ↔ many	GroupUn.10(47904-52304) GroupUn.10(57119-63763)
worm (Caenorhabditis elegans)	Secernentea	lex-1¹	Protein LEX-1	47.8(n) 38.62(a)		178146 NM_069888.5 NP_502289.2
thale cress (Arabidopsis thaliana)	eudicotyledons	AT1G05910⁶ AT3G15120⁶ (see all 4)	AAA-type ATPase family protein (see all 4)	28(a) 12(a) (see all 4)	possible ortholog 1 ↔ many (see all 4)	1(1790224-1796647) 3(5088366-5095482)
rice (Oryza sativa)	Liliopsida	Os.8886²	Oryza sativa (japonica cultivar-group) cDNA clone0 more	71.36(n)		AK099978.1

ENSEMBL Gene Tree for ATAD2 (if available)
TreeFam Gene Tree for ATAD2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ATAD2 gene

ATAD2B²

6 SIMAP similar genes for ATAD2 using alignment to 3 protein entries: ATAD2_HUMAN (see all proteins):

PSMC1 PSMC5 PSMC2 PSMC6 ATAD2B PSMC3

ATAD2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 8 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs146240983^1,2		--	124331891(+)	`AGACAA/TAACAC`	1	--	ds500¹		0	--	--	--	--
rs115548569^1,2	F,	--	124331959(+)	`ATGTAC/GCATAT`	1	--	ds500¹		1		WA	118
rs192814526^1,2		--	124332214(+)	`TGTATC/TTCCAG`	1	--	ut3¹		0	--	--	--	--
rs139263017^1,2		--	124332254(+)	`GACTGA/GCATTG`	1	--	ut3¹		0	--	--	--	--
rs185528108^1,2		--	124332451(+)	`AGCTAC/TTTCAC`	1	--	ut3¹		0	--	--	--	--
rs112308623^1,2	C,	--	124332475(+)	`GAATGT/ACTTCT`	1	--	ut3¹		2		CSA WA	120
rs117698329^1,2		--	124332556(+)	`CCATTA/CATATA`	1	--	ut3¹		1		NA	120
rs4006509^1,2	H	--	124332701(-)	`TGTGTT/AAATAA`	1	--	ut3¹		4		NS EA	418
rs78146742^1,2		--	124332710(+)	`CATTTA/GTTGTG`	1	--	ut3¹		0	--	--	--	--
rs112189199^1,2		--	124332742(+)	`CAAGAA/TATATT`	1	--	ut3¹		2		CSA WA	120

HapMap Linkage Disequilibrium report for ATAD2 (124332090 - 124428590 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ATAD2: --

SABiosciences Cancer Mutation PCR Assays

1 SABiosciences qBiomarker Copy Number PCR Array containing ATAD2:

Ovarian Cancer

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATAD2

DNA2.0 Custom Variant and Variant Library Synthesis for ATAD2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ATAD2 for disorders           About GeneDecksing

OMIM gene information: 611941    OMIM disorders: --

15 diseases for ATAD2:    About MalaCards

anogenital venereal wart human immunodeficiency virus infectious disease genital herpes gonorrhea

intrahepatic cholangiocarcinoma cholangiocarcinoma colon cancer immunodeficiency

osteosarcoma lung cancer prostate cancer breast cancer

prostatitis tuberculosis mycobacterium tuberculosis

3 diseases from the University of Copenhagen DISEASES database for ATAD2:

Genital herpes Human immunodeficiency virus infectious disease Gonorrhea

Export disorders for ATAD2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ATAD2 gene, integrated from 9 sources (see all 35):
(articles sorted by number of sources associating them with ATAD2)

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ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification. (PubMed id 17998543)^{1, 2} Zou J.X.... Chen H.-W. (2007)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. (PubMed id 15334068)^{1, 2} Petroziello J.... Carter P. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (2002)
Direct cooperation between androgen receptor and E2F1 reveals a common regulation mechanism for androgen-responsive genes in prostate cells. (PubMed id 22771493)¹ Altintas D.M....Samarut J. (2012)
Histone recognition and large-scale structural analysis of the human bromodomain family. (PubMed id 22464331)² Filippakopoulos P.... Knapp S. (2012)
Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C....Cristea I.M. (2012)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 29028	HGNC: 30123	AceView: ATAD2	Ensembl:ENSG00000156802	euGenes: HUgn29028
ECgene: ATAD2	H-InvDB: ATAD2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ATAD2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ATAD2 gene
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Patent Information for ATAD2 gene:
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ATPase family, AAA domain containing 2

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ATAD2 Gene

ATPase family, AAA domain containing 2

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