ARHGAP1 Gene
protein-coding GIFtS: 62
GCID: GC11M046698
|
|
Rho GTPase activating protein 1
| |
Aliases
for ARHGAP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rho GTPase Activating Protein 11 2 | | Cdc42GAP1 | | CDC42GAP1 2 3 5 | | RhoGAP1 | | RHOGAP12 3 5 | | RHOGAP2 | | P50rhoGAP1 | | GTPase-Activating Protein RhoGAP2 | | Rho-Related Small GTPase Protein Activator2 3 | | GTPase-Activating Protein, Rho, 12 | | Rho-Type GTPase-Activating Protein 12 3 | | Rho GTPase-Activating Protein 12 | | CDC42 GTPase-Activating Protein2 3 | | P50-RhoGAP1 | | GTPase-Activating Protein RhoOGAP2 3 | | |
Export aliases for ARHGAP1 gene to outside databasesPrevious GC identifers: GC11M048679 GC11M047576 GC11M046730 GC11M046662 GC11M046655 GC11M046404 |
Summaries
for ARHGAP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ARHGAP1:
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP)metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated proteinfamily members. (provided by RefSeq, Aug 2012)
UniProtKB/Swiss-Prot: RHG01_HUMAN, Q07960Function: GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-boundstate. Cdc42 seems to be the preferred substrate
Gene Wiki entry for ARHGAP1
|
Genomic Views
for ARHGAP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ARHGAP1 gene promoter:
CREB PPAR-gamma1 AP-1 deltaCREB ATF-2 PPAR-gamma2 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARHGAP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p11.2 Ensembl cytogenetic band: 11p11.2 HGNC cytogenetic band: 11p11.2ARHGAP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M046698: view genomic region
(about GC identifiers)
Start:
|
46,698,630 bp from pter |
End:
|
46,722,165 bp from pter |
Size:
|
23,536 bases |
Orientation:
|
minus strand |
|
Proteins
for ARHGAP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RHG01_HUMAN, Q07960 (See
protein sequence)Recommended Name: Rho GTPase-activating protein 1 Size: 439 amino acids; 50436 Da
Subunit: Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with BNIPL
Subcellular location: Cytoplasm
Sequence caution: Sequence=AAA16142.1; Type=Erroneous initiation;
6 PDB 3D structures from  and Proteopedia  for ARHGAP1:1AM4 (3D)
1GRN (3D)
1OW3 (3D)
1RGP (3D)
1TX4 (3D)
2NGR (3D)
Secondary accessions: D3DQQ6Explore the universe of human proteins at neXtProt for ARHGAP1: NX_Q07960
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q07960
ARHGAP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004299.1
ENSEMBL proteins: ENSP00000310491 ENSP00000434883 ENSP00000432794 Reactome Protein details: Q07960
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
ARHGAP1 for ontologies About GeneDecksing
ARHGAP1 Antibody Products:
Assay Products for ARHGAP1: |
Protein
Domains /
Families
for ARHGAP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARHGAP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q07960ProtoNet protein and cluster: Q07960 2 Blocks protein families: IPB000198 RhoGAP domain IPB001251 Cellular retinaldehyde-binding (CRAL)/Triple function domain (TRIO)
UniProtKB/Swiss-Prot: RHG01_HUMAN, Q07960Similarity: Contains 1 CRAL-TRIO domainSimilarity: Contains 1 Rho-GAP domain |
Function
for ARHGAP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RHG01_HUMAN, Q07960Function: GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-boundstate. Cdc42 seems to be the preferred substrate Genatlas biochemistry entry for ARHGAP1:Rho/CDC42 GTPase activating protein 1,ubiquitously expressed
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ARHGAP1 (NM_004308) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARHGAP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGAP1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
ARHGAP1 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for ARHGAP1:
Animal Models:
Mouse knock-out Arhgap1tm1Yizh for ARHGAP1
15 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Arhgap1):
ARHGAP1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ARHGAP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | G-protein signaling Regulation of RAC1 activity | | | 2 | G-protein signaling_RhoA regulation pathway | | | 3 | Actin Nucleation by ARP-WASP Complex | | | 4 | Cell death signalling via NRAGE, NRIF and NADE | | | 5 | G12-G13 in Cellular Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for ARHGAP1
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ARHGAP1
3  GeneGo (Thomson Reuters) Pathways for ARHGAP1
2  BioSystems Pathways for ARHGAP1
3 
Reactome Pathways for ARHGAP1
ARHGAP1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ARHGAP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/85 Interacting proteins for ARHGAP1 (Q079601, 2, 3 ENSP000003104914) via UniProtKB, MINT, STRING, and/or I2D (see all 85)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007264 | small GTPase mediated signal transduction |
TAS | -- | | GO:0007266 | Rho protein signal transduction |
TAS | 8253717 | | GO:0032321 | positive regulation of Rho GTPase activity |
-- | -- | | GO:0032855 | positive regulation of Rac GTPase activity |
-- | -- | | GO:0043087 | regulation of GTPase activity |
-- | -- |
ARHGAP1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ARHGAP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ARHGAP1 for compounds About GeneDecksing
 Browse Tocris compounds for ARHGAP1
6 Novoseek chemical compound relationships for ARHGAP1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| gtp |
67.5 |
10 |
16784226 (2), 9338791 (2), 9548756 (2), 12501193 (1) (see all 6) |
| gdp |
56.6 |
5 |
9338791 (2), 10555980 (1), 9548756 (1), 17272280 (1) |
| arginine |
30.1 |
6 |
12454018 (2), 12501193 (1), 9846874 (1), 9893994 (1) (see all 5) |
| fluoride |
10.6 |
4 |
10555980 (2), 9893994 (2) |
| tyrosine |
9.85 |
3 |
12788081 (1), 12454018 (1), 11238453 (1) |
| magnesium |
0 |
1 |
9548756 (1) |
Search CenterWatch for drugs/clinical trials and news about ARHGAP1 / RHG01
|
Transcripts
for ARHGAP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ARHGAP1 gene: NM_004308.3 Unigene Cluster for ARHGAP1: Rho GTPase activating protein 1 Hs.138860 [show with all ESTs]Unigene Representative Sequence: NM_0043087 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000311956(uc001ndd.3) ENST00000526423 ENST00000528837 ENST00000525488
ENST00000527588(uc009yle.1) ENST00000529960 ENST00000524594(uc009ylf.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ARHGAP1 (NM_004308) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARHGAP1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGAP1 |
Additional cDNA sequence: AK126404.1 AK298562.1 AK307296.1 AK310605.1 BC018118.1 U02570.1 U62794.1 Z23024.1 16 DOTS entries: DT.85104680 DT.92437297 DT.97863725 DT.207853 DT.85104681 DT.92437304 DT.100780579 DT.100780581 DT.120751088 DT.120751096 DT.120751099 DT.91975067 DT.99994218 DT.100730095 DT.95219439 DT.97794661 24/291 AceView cDNA sequences (see all 291): BQ671698 R63303 BM721831 H44217 BU859034 BU077641 BM708950 BM511692 BM876179 BI711158 BQ027035 BC018118 NM_004308 BM894250 CA417795 BU169971 BQ182091 CD370332 U02570 BM876170 AJ346003 BU740030 BU731610 AI826515
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGAP1 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | | | | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | | | | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14b |
|---|
|
| SP1: | | | |
| SP2: | | | |
| SP3: | | | |
| SP4: | | | |
| SP5: | | |
ECgene alternative splicing isoforms for ARHGAP1
|
Expression
for ARHGAP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARHGAP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATTTCACCG
About this image
See ARHGAP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARHGAP1
SOURCE GeneReport for Unigene cluster: Hs.138860
UniProtKB/Swiss-Prot: RHG01_HUMAN, Q07960Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for ARHGAP1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGAP1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARHGAP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGAP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGAP1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP1 |
Orthologs
for ARHGAP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ARHGAP1 gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ARHGAP11 |
Rho GTPase activating protein 1 |
76.53(n)
82.52(a) |
|
428865 XM_426422.3 XP_426422.2 |
lizard
(Anolis carolinensis) |
Reptilia |
ARHGAP16 |
-- |
78(a) |
1 ↔ 1 |
1(43049635-43077785) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BC044312.12 |
-- |
76.57(n) |
|
BC044312.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
BI428602.12 |
-- |
78.2(n) |
|
BI428602.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
RhoGAP68F1 , 3 |
Rho GTPase activator3
CG6811-PA1 |
37(a)3
50.43(n)1
36.17(a)1 |
|
393851 NM_140295.21 NP_648552.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
W02B12.83
rga-11 |
GTPase-activating (rhoGAP) like protein3
Protein RGA-11 |
39(a)3
50.42(n)1
41.5(a)1 |
|
II(11464575-11466218)3
1747511 NM_001027219.41 NP_001022390.11 |
ENSEMBL Gene Tree for ARHGAP1 (if available)
TreeFam Gene Tree for ARHGAP1 (if available) |
Paralogs
for ARHGAP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ARHGAP1 gene
- PRUNE22 BNIP22 ARHGAP82 ATCAY2 PRR5-ARHGAP82 BNIPL2
14 SIMAP similar genes for ARHGAP1 using alignment to 3 protein entries: RHG01_HUMAN (see all proteins):BPGAP1 ARHGAP8 LOC553158 PRR5-ARHGAP8 FAM13B ARHGAP12
FAM13A CHN2 ARHGAP5 ARHGAP24 ARHGAP9 BNIP2
PRUNE2 ARHGAP21
ARHGAP1 for paralogs About GeneDecksing
|
Genomic Variants
for ARHGAP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ARHGAP1 (46698630 - 46722165 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ARHGAP1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGAP1 |
|
Disorders
/ Diseases
for ARHGAP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ARHGAP1 for disorders About GeneDecksing
OMIM gene information: 602732
OMIM disorders: --
20/23  diseases for ARHGAP1 (see all 23): About MalaCardsmicrophthalmia with linear skin defects nephrogenic diabetes insipidus wiskott-aldrich syndrome diabetes insipidus
oculocerebrorenal syndrome intellectual disability transitional cell carcinoma microphthalmia
squamous cell carcinoma hepatocellular carcinoma fanconi syndrome noma
spasticity liver cancer carcinoma ovarian cancer
breast carcinoma lung cancer immunodeficiency chronic myeloid leukemia
4 Novoseek disease relationships for ARHGAP1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: ARHGAP1 (2 documents)
Export disorders for ARHGAP1 gene to outside databases
|
Publications
for ARHGAP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARHGAP1 gene, integrated from 9 sources (see all 139):
(articles sorted by number of sources associating them with ARHGAP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of rhoGAP. A GTPase-activating protein for rho- related small GTPases. (PubMed id 8288572)1, 2, 3, 9 Lancaster C.A....Hall A. (1994)
- BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis. (PubMed id 12901880)1, 2, 9 Qin W.... Gu J. (2003)
- The structure of the GTPase-activating domain from p50rhoGAP. (PubMed id 9009196)1, 2, 9 Barrett T....Eccleston J.F. (1997)
- Exportin 7 defines a novel general nuclear export pathway. (PubMed id 15282546)1, 2 Mingot J.-M.... Goerlich D. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Crystal structure of a small G protein in complex with the GTPase- activating protein rhoGAP. (PubMed id 9262406)1, 2 Rittinger K.... Smerdon S.J. (1997)
- Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain. (PubMed id 8253717)1, 2 Barfod E.T....Ashkenazi A. (1993)
- Bcr encodes a GTPase-activating protein for p21rac. (PubMed id 1903516)1, 2 Diekmann D.... Hall A. (1991)
- Purification and N-terminal sequence of the p21rho GTPase-activating protein, rho GAP. (PubMed id 1905930)1, 2 Garrett M.D.... Hall A. (1991)
- Regulation of RhoA GTP hydrolysis by the GTPase-activating proteins p190, p50RhoGAP, Bcr, and 3BP-1. (PubMed id 9548756)1, 9 Zhang B. and Zheng Y. (1998)
|
External Searches for ARHGAP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ARHGAP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARHGAP1 gene
(According to HUGE)
About This Section
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Specialized Databases showing ARHGAP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for ARHGAP1 gene:
Search GeneIP for patents involving ARHGAP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ARHGAP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ARHGAP1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARHGAP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGAP1 | | | OriGene Protein Over-expression Lysate for ARHGAP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ARHGAP1 | | OriGene 3'-UTR Clone for ARHGAP1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ARHGAP1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ARHGAP1 | | OriGene Custom Protein Services for ARHGAP1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARHGAP1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGAP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARHGAP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGAP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGAP1 |
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| | | | Search Tocris compounds for ARHGAP1 |
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 | | | ARHGAP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP1 |
|  |  |  | | | | ThermoFisher Antibodies for ARHGAP1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGAP1 |
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