ACY3 Gene
protein-coding GIFtS: 55
GCID: GC11M067411
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aspartoacylase (aminocyclase) 3
| |
Aliases for ACY3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Aspartoacylase (Aminocyclase) 31 2 | | Aminoacylase-33 | | ACY-31 2 3 | | Aspartoacylase-21 | | HCBP11 2 3 | | ASPA23 | | Acylase III2 3 | | Aminoacylase-33 | | Hepatitis C Virus Core-Binding Protein 12 3 | | EC 3.5.1.-3 | | HCV Core-Binding Protein 12 3 | | EC 3.5.1.158 | | MGC97401 | | |
Export aliases for ACY3 gene to outside databasesPrevious GC identifers: GC11M067166 GC11M063739 |
Summaries for ACY3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: ACY3_HUMAN, Q96HD9Function: Plays an important role in deacetylating mercapturic acids in kidney proximal tubules (By similarity)
|
Genomic Views for ACY3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ACY3 gene promoter: Pax-5 MyoD Lmo2 Roaz E47 PPAR-alpha Hand1 NF-kappaB1 ATF Other transcription factors
Search SABiosciences Chromatin IP Primers for ACY3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACY3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13.2 Ensembl cytogenetic band: 11q13.2 HGNC cytogenetic band: 11q13ACY3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M067411: view genomic region
(about GC identifiers)
Start:
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67,410,026 bp from pter |
End:
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67,418,130 bp from pter |
Size:
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8,105 bases |
Orientation:
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minus strand |
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Proteins for ACY3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ACY3_HUMAN, Q96HD9 (See
protein sequence)Recommended Name: Aspartoacylase-2 Size: 319 amino acids; 35241 Da
Cofactor: Binds 1 zinc ion per subunit (Potential)
Subunit: Homotetramer (By similarity). Interacts with HCV core protein
Subcellular location: Apical cell membrane; Peripheral membrane protein. Cytoplasm. Note=Predominantly localized in theapical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expresseddiffusely throughout the cytoplasmExplore the universe of human proteins at neXtProt for ACY3: NX_Q96HD9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96HD9 4/5 DME Specific Peptides for ACY3 (Q96HD9) (see all 5)
ACY3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_542389.1 ENSEMBL proteins: ENSP00000255082 ENSP00000434270 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ACY3 for ontologies About GeneDecksing
ACY3 Antibody Products: Assay Products for ACY3: |
Protein
Domains / Families for ACY3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ACY3 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96HD9ProtoNet protein and cluster: Q96HD9 1 Blocks protein family: IPB007036 Succinylglutamate desuccinylase/aspartoacylase
UniProtKB/Swiss-Prot: ACY3_HUMAN, Q96HD9Similarity: Belongs to the AspA/AstE family. Aspartoacylase subfamily |
Function for ACY3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ACY3_HUMAN, Q96HD9Function: Plays an important role in deacetylating mercapturic acids in kidney proximal tubules (By similarity)Enzyme Numbers (IUBMB): EC 3.5.1.-1 EC 3.5.1.152
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACY3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACY3 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ACY3 (NM_080658) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACY3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACY3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACY3 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004046 | aminoacylase activity |
IEA | -- | | GO:0016788 | hydrolase activity, acting on ester bonds |
IEA | -- | | GO:0042802 | identical protein binding |
IEA | -- | | GO:0046872 | metal ion binding |
IEA | -- |
ACY3 for ontologies About GeneDecksing
|
Pathways & Interactions for ACY3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Alanine, aspartate and glutamate metabolism | | | 2 | Histidine metabolism | |
Pathway sources See GeneCards unified pathways Show all pathways
2
Kegg Pathways (Kegg details for ACY3):
ACY3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACY3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/31 Interacting proteins for ACY3 (Q96HD93 ENSP000002550824) via UniProtKB, MINT, STRING, and/or I2D (see all 31)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0019048 | virus-host interaction |
IEA | -- | | GO:0044419 | interspecies interaction between organisms |
-- | -- |
ACY3 for ontologies About GeneDecksing
|
Drugs & Compounds for ACY3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ACY3
10/14 HMDB Compounds for ACY3 (see all 14) About this table
1 DrugBank Compound for ACY3 About this table
Search CenterWatch for drugs/clinical trials and news about ACY3 
|
Transcripts for ACY3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ACY3 gene: NM_080658.1 Unigene Cluster for ACY3: Aspartoacylase (aminocyclase) 3 Hs.126265 [show with all ESTs]Unigene Representative Sequence: BC0086892 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000255082(uc001omq.3) ENST00000529256
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACY3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACY3 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ACY3 (NM_080658) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACY3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACY3  |
Additional cDNA sequence: AF359506.1 AK308710.1 AY032593.1 AY040761.1 AY169233.1 BC008689.1 3 DOTS entries: DT.106820 DT.100751214 DT.95363314 24/34 AceView cDNA sequences (see all 34): BC008689 BX099342 AY169233 CB142925 NM_080658 AI984323 AY040761 BQ066416 BM923441 AA912995 AI651548 BI762818 BI762689 BP346760 CB131482 BE870188 AA873854 R55423 AI949904 AI393205 AI480405 BE501441 AI478333 AW205296 GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ACY3 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ACY3
|
Expression for ACY3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ACY3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTCCTTGCCA
About this image See ACY3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ACY3
SOURCE GeneReport for Unigene cluster: Hs.126265 SABiosciences Custom PCR Arrays for ACY3
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ACY3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ACY3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACY3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACY3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACY3 |
Orthologs for ACY3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ACY3 gene from 2/9 species (see all 9) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
lizard (Anolis carolinensis) |
Reptilia |
ACY36 |
-- |
57(a) |
1 ↔ 1 |
1(93381970-93387571) |
zebrafish (Danio rerio) |
Actinopterygii |
acy3.11 |
aspartoacylase (aminocyclase) 3.1 |
52.84(n) 46.49(a) |
  |
791456 NM_001145361.1 NP_001138833.1 |
ENSEMBL Gene Tree for ACY3 (if available) TreeFam Gene Tree for ACY3 (if available)  |
Paralogs for ACY3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ACY3 gene
- ASPA2
2 SIMAP similar genes for ACY3 using alignment to 2 protein entries: ACY3_HUMAN (see all proteins):HCBP1 ASPA
ACY3 for paralogs About GeneDecksing
|
Genomic Variants for ACY3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 11 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ACY3 (67410026 - 67418130 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for ACY3 2 CNVs: 53128 5275  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACY3 |
|
Disorders
/ Diseases for ACY3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ACY3 for disorders About GeneDecksing
OMIM gene information: 614413
OMIM disorders: --
2 diseases for ACY3: About MalaCardshepatitis c hepatitis 1 disease from the University of Copenhagen DISEASES database for ACY3:Canavan disease Export disorders for ACY3 gene to outside databases
|
Publications for ACY3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ACY3 gene integrated from 9 sources: (articles sorted by number of sources associating them with ACY3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification of a novel protein binding to hepatitis C virus core protein. (PubMed id 19486448)1, 2 Chen Y.R.... Liu M. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Structural characterization, tissue distribution, and functional expression of murine aminoacylase III. (PubMed id 14656720)1, 3 Pushkin A....Kurtz I. (2004)
- Identification of NPC2 protein as interaction molecul e with C2 domain of human Nedd4L. (PubMed id 19664597)1 Araki N....Umemura S. (2009)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)
- How many drug targets are there? (PubMed id 17139284)7 Overington J.P....Hopkins A.L. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for ACY3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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|
Genome Databases showing ACY3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ACY3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ACY3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ACY3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ACY3 gene: Search GeneIP for patents involving ACY3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ACY3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | OriGene Antibodies for ACY3 | | OriGene shRNA RFP for ACY3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ACY3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ACY3 | | OriGene Protein Over-expression Lysate for ACY3 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ACY3 | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACY3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACY3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for ACY3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ACY3 | | OriGene Custom Protein Services for ACY3 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ACY3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACY3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACY3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ACY3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACY3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACY3 |
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 |  |  |  | |
| | | Search Tocris compounds for ACY3 |
| |  |  |  |  | | | | | Recombinant Protein for ACY3 |
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 | | ACY3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACY3 |
|  |  |  | | | Search ThermoFisher Antibodies for ACY3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACY3 |
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